Prab at 17:07, 22 March 2025

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'''Fields' disease''' is considered to be one of the rarest known [[diseases]] in the world, with only two diagnosed cases. The frequency of this disease is therefore 1 in approximately 3.75 billion (although since the disease manifested in identical twins, the actual frequency is 1 in approximately 7.5 billion). It is named after [[Welsh people|Welsh]] twins Catherine and Kirstie Fields, of [[Llanelli]]. Fields' disease is a [[neuromuscular disease]], causing muscular degeneration.<ref>{{cite news |url=http://news.bbc.co.uk/1/hi/wales/south_west/4335454.stm |title=Rare condition named after twins |work=[[BBC News]] |date=13 October 2005 }}</ref>

The disease was first noticed when the twins were four. Doctors have been unable to identify it and have not been able to match it to any known diseases. As a result, the Fields sisters have undergone numerous tests, but no treatment has yet been found. No definitive cause has been determined, and doctors have generally concluded that they were born with it.

==Prognosis==
The disease appears to be progressive in nature. The Fields twins started having problems when they were four years old. By the time they had reached the age of nine, they were having difficulty walking and needed [[Walker (mobility)|frames]] to assist them with walking. Their muscles have been gradually deteriorating over time. The disease affects the twins' nerves, causing them to make involuntary muscle movements such as trembling in the hands.

The extent of the disease is still unknown as the two women are only 23. However, the disease has had no apparent effect on their [[brain]]s or personalities. Doctors do not know if the disease is fatal and, if so, what the life expectancy of one with this disease is. If the cause of the disease is genetic, there is a chance that the twins could pass it on to their future children.

===The twins' lives===
The twins require the use of wheelchairs for mobility and are unable to speak without the assistance of electronic speaking aids.<ref>[https://www.mirror.co.uk/news/uk-news/twin-girls-talk-again-after-1321683 Daily Mirror, 12 September 2012]</ref> They experience persistent and painful muscle spasms which are worsened by emotional distress. They are currently living with their parents, with the assistance of hospice workers. Doctors continue to administer [[Medical test|tests]] to the twins in search of a treatment.

==References==
{{reflist}}

{{Diseases of myoneural junction and muscle}}

[[Category:Myoneural junction and neuromuscular diseases]]
[[Category:Ailments of unknown cause]]
[[Category:Rare diseases]]

Fields' disease - Revision history

Prab at 17:07, 22 March 2025

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