Deepika vegiraju: Created page with "'''Other Names:''' Non-amyloid fibrillary glomerulopathy; Congo red-negative amyloidosis-like glomerulopathy; Non-amyloid fibrillary glomerulonephritis Fibrillary glomerulone..."

2020-11-10T17:29:07Z

Created page with "'''Other Names:''' Non-amyloid fibrillary glomerulopathy; Congo red-negative amyloidosis-like glomerulopathy; Non-amyloid fibrillary glomerulonephritis Fibrillary glomerulone..."

New page

'''Other Names:''' Non-amyloid fibrillary glomerulopathy; Congo red-negative amyloidosis-like glomerulopathy; Non-amyloid fibrillary glomerulonephritis

Fibrillary glomerulonephritis is an uncommon cause of [[glomerular]] disease. A more rare disorder known as immunotactoid [[glomerulpathy]] is a very similar condition. Both disorders probably result from deposits derived from [[immunoglobulins]] but in most cases the cause is idiopathic (unknown).

== '''Cause''' ==
Both fibrillary glomerulonephritis and immunotactoid glomerulopathy have been associated with [[hepatitis C]] virus infection and with malignancy and [[autoimmune disease]]. Because of this, patients should be screened for these conditions.

== '''Signs and symptoms''' ==
The signs and symptoms include blood ([[hematuria]]) and protein ([[proteinuria]]) in the urine, kidney insufficiency and high blood pressure.

== '''Diagnosis''' ==
The diagnosis is made with a kidney [[biopsy]] and by [[electron microscopy]]. Fibrillary glomerulonephritis and immunotactoid glomerulopathy can be differentiated from each other by electron microscopy; the fibrils in fibrillary glomerulonephritis are smaller and randomly oriented as opposed to the larger and often organized fibrils of immunotactoid glomerulopathy.

== '''Treatment''' ==
Treatment is generally determined by the severity of the kidney problems.
The most common form of treatment was [[steroids]], with or without a second agent, including most notably [[cyclophosphamide]] or [[rituximab]]. A benefit of [[immunosuppression]] could not be detected in these small, retrospective studies in which patients with more severe disease were more likely to have been treated.

== '''Prognosis''' ==
The prognosis for patients with FGN remains poor, with limited data to suggest optimal therapy.

{{rarediseases}}
{{stub}}

Fibrillary glomerulonephritis - Revision history

Deepika vegiraju: Created page with "'''Other Names:''' Non-amyloid fibrillary glomerulopathy; Congo red-negative amyloidosis-like glomerulopathy; Non-amyloid fibrillary glomerulonephritis Fibrillary glomerulone..."