Deepika vegiraju at 15:52, 24 July 2021

2021-07-24T15:52:00Z

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== '''What is Ferric maltol?''' ==

Ferric maltol (ACCRUFER) is an iron replacement product indicated for the treatment of iron deficiency in adults.

[[File:Ferric maltol.svg|thumb]]

== '''What are the uses of this medicine?''' ==

* This medicine is used for the treatment of iron deficiency in adults.

== '''How does this medicine work?''' ==

* ACCRUFER '''delivers iron for uptake across the intestinal wall''' and transfer to [[transferrin]] and [[ferritin]].

== '''Who Should Not Use this medicine ?''' ==

This medicine cannot be used in patients with:
* [[Hypersensitivity]] to the active substance or to any of the excipients
* [[Hemochromatosis]] and other iron overload syndromes
* Receiving repeated blood transfusions

== '''What drug interactions can this medicine cause?''' ==

* Concomitant use of some drugs may reduce the bioavailability of iron after administration of ACCRUFER. Separate the administration of ACCRUFER from these drugs.
* Avoid concomitant use of ACCRUFER with [[dimercaprol]].
* Concomitant use of ACCRUFER may decrease the bioavailability of some drugs. Separate administration of ACCRUFER from certain oral medications. Monitor clinical responses as appropriate.
* Some medicines may need to be taken at least 4 hours before or 4 hours after you have taken your ACCRUFER dose. Ask your healthcare provider for a list of these medicines if you are not sure if you take one of these medicines.

== '''Is this medicine FDA approved?''' ==

* It was approved for use in the United States in 2019.

== '''How should this medicine be used?''' ==

'''Recommended Dosage'''
* The recommended dosage of ACCRUFER is '''30 mg twice daily''', taken 1 hour before or 2 hours after a meal.

'''Administration'''
* Take ACCRUFER exactly as your healthcare provider tells you to.
* Take ACCRUFER 2 times a day on an empty stomach 1 hour before or 2 hours after meals.
* Swallow ACCRUFER capsules whole. Do not open, break, or chew ACCRUFER capsules.
* In case of accidental overdose, call your healthcare provider or go to the nearest hospital emergency room right away.

== '''What are the dosage forms and brand names of this medicine?''' ==

This medicine is available in fallowing doasage form:
* '''As Capsules: '''30 mg

This medicine is available in fallowing brand namesː
*'''ACCRUFER'''

=='''What side effects can this medication cause?'''==

The most common side effects of this medicine include:
* [[flatulence]]
* diarrhea
* constipation
* feces discolored
* abdominal pain
* nausea
* vomiting
* abdominal discomfort/distension

ACCRUFER may cause serious side effects, including:
* Increased risk of [[inflammatory bowel disease]] (IBD) flare
* Too much iron stored in your body ([[iron overload]])
* Risk of overdose in children due to accidental swallowing

==''' What special precautions should I follow?''' ==

* Avoid use of ACCRUFER in patients with an active [[inflammatory bowel disease (IBD)]] flare, as there is potential risk of increased inflammation in the gastrointestinal tract.
* Do not administer ACCRUFER to patients with evidence of iron overload or patients receiving intravenous iron. Assess iron parameters prior to initiating ACCRUFER and monitor iron parameters while on therapy.
* Accidental overdose of iron-containing products is a leading cause of fatal poisoning in children under 6. Keep this product out of reach of children. In case of accidental overdose, call a doctor or poison control center immediately.

== '''What to do in case of emergency/overdose?''' ==

* Acute iron ingestion of 20 mg/kg elemental iron is potentially toxic and 200- 250 mg/kg is potentially fatal.
* Early signs and symptoms of iron overdose may include nausea, vomiting, abdominal pain and diarrhea. In more serious cases there may be evidence of hypoperfusion, [[metabolic acidosis]] and systemic toxicity.
* Dosages of ACCRUFER in excess of iron needs may lead to accumulation of iron in storage sites leading to [[hemosiderosis]].

== '''Can this medicine be used in pregnancy?''' ==

* It is not known if ACCRUFER will harm your unborn baby.
* An overdose of iron in pregnant women may carry a risk for spontaneous abortion, gestational diabetes and fetal malformation.

=='''Can this medicine be used in children?'''==

* Safety and effectiveness of ACCRUFER have not been established in pediatric patients.

== '''What are the active and inactive ingredients in this medicine?''' ==

'''Active ingredient:''' ferric maltol
'''Inactive ingredients:'''
Capsule: colloidal anhydrous silica, crospovidone (Type A), lactose monohydrate, magnesium stearate, sodium lauryl sulfate
Capsule Shell: FD&C Blue No. 1 FD&C Red No. 40, FD&C Yellow 6, hypromellose, titanium dioxide.
Ink: ammonium hydroxide, ethanol, iron oxide black, propylene glycol

== '''Who manufactures and distributes this medicine?''' ==

* Distributed by Shield Therapeutics Inc

== '''What should I know about storage and disposal of this medication?''' ==

* Store ACCRUFER at room temperature between 68°F to 77°F (20°C to 25°C).
* Keep ACCRUFER and all medicines out of reach of children.

{{Antianemic preparations}}
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[[Category:Iron(III) compounds]]
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Ferric maltol - Revision history

Deepika vegiraju at 15:52, 24 July 2021