https://wikimd.org/index.php?action=history&feed=atom&title=FOX_proteinsFOX proteins - Revision history2026-04-25T01:44:16ZRevision history for this page on the wikiMediaWiki 1.44.2https://wikimd.org/index.php?title=FOX_proteins&diff=6505737&oldid=prevPrab: CSV import2025-03-17T11:40:40Z<p>CSV import</p>
<table style="background-color: #fff; color: #202122;" data-mw="interface">
<col class="diff-marker" />
<col class="diff-content" />
<col class="diff-marker" />
<col class="diff-content" />
<tr class="diff-title" lang="en">
<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td>
<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 11:40, 17 March 2025</td>
</tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l17">Line 17:</td>
<td colspan="2" class="diff-lineno">Line 17:</td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{biology-stub}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{biology-stub}}</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{No image}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{No image}}</div></td></tr>
<tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">__NOINDEX__</ins></div></td></tr>
</table>Prabhttps://wikimd.org/index.php?title=FOX_proteins&diff=6233458&oldid=prevPrab: CSV import2025-02-10T17:10:29Z<p>CSV import</p>
<table style="background-color: #fff; color: #202122;" data-mw="interface">
<col class="diff-marker" />
<col class="diff-content" />
<col class="diff-marker" />
<col class="diff-content" />
<tr class="diff-title" lang="en">
<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td>
<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 17:10, 10 February 2025</td>
</tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l16">Line 16:</td>
<td colspan="2" class="diff-lineno">Line 16:</td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[[Category:Protein families]]</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[[Category:Protein families]]</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{biology-stub}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{biology-stub}}</div></td></tr>
<tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">{{No image}}</ins></div></td></tr>
</table>Prabhttps://wikimd.org/index.php?title=FOX_proteins&diff=5585972&oldid=prevPrab: CSV import2024-04-13T21:12:19Z<p>CSV import</p>
<p><b>New page</b></p><div>'''FOX proteins''' are a family of [[transcription factors]] that play important roles in regulating the expression of genes involved in cell growth, proliferation, differentiation, and longevity. The name "FOX" comes from "Forkhead box," due to the similarity to the forkhead transcription factor in [[Drosophila]]. Members of the FOX protein family are characterized by a distinct DNA-binding domain known as a forkhead box, which binds to specific sequences on DNA to regulate the transcription of target genes.<br />
<br />
== Function ==<br />
FOX proteins are involved in a wide range of biological processes. They are critical in the development of tissues and organs during [[embryogenesis]], maintaining the balance between cell growth and apoptosis (programmed cell death), and in the regulation of the immune system. Each member of the FOX protein family has a unique role, depending on its specific DNA binding affinity and the tissues where it is expressed. For example, FOXO proteins are key players in the regulation of [[metabolism]], [[cell cycle]] control, and cellular stress responses, contributing to the longevity and cancer resistance of certain organisms.<br />
<br />
== Classification ==<br />
The FOX protein family is classified into several subclasses, designated as FOXA through FOXS, based on differences in their DNA-binding domain sequences and functions. This classification helps in understanding the specific roles and mechanisms of action of different FOX proteins.<br />
<br />
== Clinical Significance ==<br />
Several FOX proteins have been implicated in human diseases. Mutations or dysregulation of FOX proteins can lead to developmental disorders, cancers, and other diseases. For example, mutations in the FOXE3 gene are associated with eye disorders such as [[congenital cataracts]] and [[microphthalmia]], while aberrant expression of FOXM1 has been linked to the progression of various cancers.<br />
<br />
== Research ==<br />
Research on FOX proteins continues to uncover their complex roles in cellular processes and disease mechanisms. Understanding the function and regulation of FOX proteins offers potential therapeutic targets for treating cancer, diabetes, immune disorders, and developmental diseases.<br />
<br />
[[Category:Transcription factors]]<br />
[[Category:Protein families]]<br />
{{biology-stub}}</div>Prab