https://wikimd.com/index.php?action=history&feed=atom&title=FDX2 2026-04-08T09:19:03Z Revision history for this page on the wiki MediaWiki 1.44.2 https://wikimd.com/index.php?title=FDX2&diff=6506880&oldid=prev 2025-03-17T12:47:32Z

<p>CSV import</p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 12:47, 17 March 2025</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l27">Line 27:</td> <td colspan="2" class="diff-lineno">Line 27:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{Medicine-stub}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{Medicine-stub}}</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{No image}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{No image}}</div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">__NOINDEX__</ins></div></td></tr> </table>

Prab https://wikimd.com/index.php?title=FDX2&diff=6233056&oldid=prev 2025-02-10T17:04:37Z

<p>CSV import</p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 17:04, 10 February 2025</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l26">Line 26:</td> <td colspan="2" class="diff-lineno">Line 26:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[[Category:Mitochondrial genetics]]</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[[Category:Mitochondrial genetics]]</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{Medicine-stub}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{Medicine-stub}}</div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">{{No image}}</ins></div></td></tr> </table>

Prab https://wikimd.com/index.php?title=FDX2&diff=5411208&oldid=prev 2024-03-19T08:38:57Z

<p>CSV import</p> <p><b>New page</b></p><div>&#039;&#039;&#039;FDX2&#039;&#039;&#039; (Ferredoxin 2), also known as &#039;&#039;Adrenodoxin, mitochondrial&#039;&#039;, is a protein that in humans is encoded by the &#039;&#039;FDX2&#039;&#039; gene. This protein plays a crucial role in the mitochondrial electron transport chain, where it is involved in the transfer of electrons from NADPH to cytochrome P450 enzymes. These enzymes are involved in the synthesis of steroid hormones, detoxification, and the metabolism of drugs in the liver. The &#039;&#039;FDX2&#039;&#039; gene is located on chromosome 19 in humans.<br /> <br /> == Function ==<br /> The primary function of FDX2 is to mediate electron transfer within the mitochondria. It accepts electrons from NADPH via ferredoxin reductase and then transfers these electrons to various cytochrome P450 enzymes. This process is essential for the biosynthesis of steroid hormones such as cortisol, aldosterone, and sex steroids. Additionally, FDX2 is involved in the metabolism of xenobiotics, which are foreign substances to the body, including drugs and toxins.<br /> <br /> == Clinical Significance ==<br /> Mutations in the &#039;&#039;FDX2&#039;&#039; gene have been associated with several diseases. Deficiencies in FDX2 can lead to disorders in steroidogenesis, resulting in symptoms related to adrenal insufficiency and potentially affecting sexual development. Furthermore, alterations in the function of FDX2 may influence the metabolism of drugs and the body&#039;s response to them, which has implications for pharmacogenomics and personalized medicine.<br /> <br /> == Genetic ==<br /> The &#039;&#039;FDX2&#039;&#039; gene is located on the long (q) arm of chromosome 19 at position 13.2, from base pair 35,897,971 to base pair 35,902,203. The gene consists of several exons that encode the FDX2 protein. Variants within this gene or its regulatory regions may affect the expression or function of FDX2, leading to disease.<br /> <br /> == See Also ==<br /> * [[Cytochrome P450]]<br /> * [[Mitochondrial electron transport chain]]<br /> * [[Steroidogenesis]]<br /> * [[Adrenal insufficiency]]<br /> * [[Pharmacogenomics]]<br /> <br /> == References ==<br /> &lt;references /&gt;<br /> <br /> == External Links ==<br /> * [https://www.ncbi.nlm.nih.gov/gene/112812 NCBI Gene: FDX2]<br /> <br /> [[Category:Human proteins]]<br /> [[Category:Mitochondrial genetics]]<br /> {{Medicine-stub}}</div>

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