Deepika vegiraju at 16:52, 8 August 2023

2023-08-08T16:52:16Z

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=='''What is {{PAGENAME}}?'''==

* Erenumab ('''Aimovig'''), is a calcitonin gene-related peptide receptor antagonist.

[[File:Aimovig Autoinjector.jpg|thumb|Aimovig Autoinjector]]

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=='''What are the uses of this medicine?'''==

[[File:BI 44370 TA.svg|thumb|calcitonin gene related peptide ]]

* Erenumab ('''Aimovig'''), is indicated for the preventive treatment of migraine in adults.

=='''How does this medicine work?'''==

* It binds to the calcitonin gene-related peptide (CGRP) receptor and antagonizes CGRP receptor function thus prevent migraine attacks.

=='''Who Should Not Use this medicine?'''==

* Aimovig is contraindicated in patients with serious hypersensitivity to erenumab-aooe.

=='''Is this medicine FDA approved?'''==

* The United States Food and Drug Administration (FDA) approved the medication for the preventive treatment of migraine in adults on May 17, 2018.

== '''What drug interactions can this medicine cause?''' ==

* Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

=='''How should this medicine be used?'''==

'''Recommended dosage:'''
Recommended dosage is 70 mg once monthly; some patients may benefit from a dosage of 140 mg once monthly.

'''Administration:'''
* Aimovig is intended for patient self-administration
* Aimovig is for subcutaneous use only.
* Administer Aimovig in the abdomen, thigh, or upper arm subcutaneously.
* Do not inject into areas where the skin is tender, bruised, red, or hard.

=='''What are the dosage forms and brand names of this medicine?'''==

* Aimovig is a sterile, clear to opalescent, colorless to light yellow solution.
* Aimovig is the brand name.

=='''what to do if i missed a dose?'''==

* If a dose of Aimovig is missed, administer as soon as possible.

=='''what should I know before taking the drug'''==

* The prefilled forms has dry natural rubber (a derivative of latex), which may cause allergic reactions in individuals sensitive to latex.
* Prior to subcutaneous administration, allow Aimovig to sit at room temperature for at least 30 minutes protected from direct sunlight
* Do not warm by using a heat source such as hot water or a microwave.
* Do not shake the product.
* Do not use if the solution is cloudy or discolored or contains flakes or particles.
* Administer Aimovig in the abdomen, thigh, or upper arm subcutaneously. Do not inject into areas where the skin is tender, bruised, red, or hard.

=='''What side effects can this medication cause?'''==

The most common side effects of this medicine include:
* pain, redness, or swelling at the injection site and constipation.

Less common,but serious side effects may include:
* Allergic reactions
* Constipation with serious complications
* High blood pressure

==''' What special precautions should I follow?'''==

* Provide guidance to patients and caregivers on proper subcutaneous administration technique, including aseptic technique, and how to use the single-dose prefilled autoinjector or single-dose prefilled syringe. Instruct patients and/or caregivers to read and follow the Instructions for Use each time they use Aimovig.
* Advise patients to let Aimovig sit at room temperature for at least 30 minutes prior to administration.
* Advise patients to seek immediate medical attention if they experience any symptoms of serious or severe hypersensitivity reactions.
* Advise patients that constipation with serious complications can occur with Aimovig and that they should contact their healthcare providers if they experience severe constipation.
* Advise patients that development of hypertension and worsening of pre-existing hypertension can occur with Aimovig and that they should contact their healthcare providers if they experience elevation in their blood pressure.
* Advise patients that there is a pregnancy exposure registry that monitors pregnancy outcomes in women exposed to Aimovig during pregnancy.
* It is not known if Aimovig passes into your breast milk. Talk to your healthcare provider about the best way to feed your baby while using Aimovig.
* Erenumab therapy has not been associated with serum enzyme elevations during therapy nor has it been implicated in cases of clinically apparent drug induced liver injury with jaundice.

=='''What to do in case of emergency/overdose?'''==

*{{overdose}}
* seek emergency medical care

=='''Can this medicine be used in pregnancy?'''==

* There are no adequate data on the developmental risk associated with the use of Aimovig in pregnant women.
* There is a pregnancy registry for women who take Aimovig. The purpose of this registry is to collect information about your health and your baby's health. You may enroll yourself by calling 1-833-244-4083 or visiting https://www.genesispregnancyregistry.com/. Or you may talk to your doctor about how you can take part in this registry.

=='''Can this medicine be used in children?'''==

* Safety and effectiveness in pediatric patients have not been established.

=='''What should I know about storage and disposal of this medication?'''==

* Store refrigerated at 2°C to 8°C
* If removed from the refrigerator ,should be used within 7 days
* Do not freeze.
* Do not shake

{{migraine headache agents}}
{{coststubd}}
{{Triptans}}
{{Monoclonals for bone, musculoskeletal, circulatory, and neurologic systems}}
{{Protein and peptide receptor modulators}}
{{portal bar | Medicine}}
[[category:anti migraine drugs]]
[[category:monoclonal antibodies]]
[[category:calcitonin gene related peptide receptors antagonists]]
[[category:amgen]]
[[category:novartis brands]]

Erenumab - Revision history

Deepika vegiraju at 16:52, 8 August 2023