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<p><b>New page</b></p><div>[[File:Eptapirone.png|thumb|{{PAGENAME}}]]<br>'''Eptapirone''' is a potent and highly selective [[5-HT1A receptor]] full agonist of the [[azapirone]] chemical class. It is an [[anxiolytic]] drug that was first synthesized by [[Bristol-Myers Squibb]] in 1986. Eptapirone is structurally related to other azapirones like [[buspirone]] and [[ipsapirone]].<br />
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==Pharmacology==<br />
Eptapirone acts as a full agonist at the [[5-HT1A receptor]], meaning it can produce the maximum response possible from this receptor. This is in contrast to partial agonists, which can only produce a partial response regardless of the drug dosage. The 5-HT1A receptor is a subtype of the [[5-HT receptor]] that binds the [[neurotransmitter]] [[serotonin]], and is involved in a variety of functions including mood, anxiety, and cognition.<br />
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==Clinical Use==<br />
Eptapirone has been studied for its potential use in the treatment of [[anxiety disorders]], [[depression]], and other conditions. However, as of 2021, it is not currently approved for medical use in any country. <br />
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==Chemistry==<br />
Eptapirone belongs to the [[azapirone]] class of compounds, which are characterized by their pyrimidinylpiperazine and furanopyridine moieties. Other azapirones include [[buspirone]], [[gepirone]], and [[ipsapirone]], all of which also act as 5-HT1A receptor agonists.<br />
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==See Also==<br />
* [[5-HT1A receptor]]<br />
* [[Azapirone]]<br />
* [[Buspirone]]<br />
* [[Gepirone]]<br />
* [[Ipsapirone]]<br />
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==References==<br />
<references /><br />
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[[Category:Drugs]]<br />
[[Category:Anxiolytics]]<br />
[[Category:Azapirones]]<br />
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