https://wikimd.org/index.php?action=history&feed=atom&title=Efflux 2026-04-26T12:11:31Z Revision history for this page on the wiki MediaWiki 1.44.2 https://wikimd.org/index.php?title=Efflux&diff=6532966&oldid=prev 2025-03-22T17:02:02Z

<p></p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 17:02, 22 March 2025</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l36">Line 36:</td> <td colspan="2" class="diff-lineno">Line 36:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{dictionary-stub1}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{dictionary-stub1}}</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{No image}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{No image}}</div></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">__NOINDEX__</del></div></td><td colspan="2" class="diff-side-added"></td></tr> </table>

Prab https://wikimd.org/index.php?title=Efflux&diff=6504401&oldid=prev 2025-03-17T10:22:40Z

<p>CSV import</p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 10:22, 17 March 2025</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l36">Line 36:</td> <td colspan="2" class="diff-lineno">Line 36:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{dictionary-stub1}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{dictionary-stub1}}</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{No image}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{No image}}</div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">__NOINDEX__</ins></div></td></tr> </table>

Prab https://wikimd.org/index.php?title=Efflux&diff=6230296&oldid=prev 2025-02-10T16:19:04Z

<p>CSV import</p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 16:19, 10 February 2025</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l35">Line 35:</td> <td colspan="2" class="diff-lineno">Line 35:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[[Category:Pharmacology]]</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[[Category:Pharmacology]]</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{dictionary-stub1}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{dictionary-stub1}}</div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">{{No image}}</ins></div></td></tr> </table>

Prab https://wikimd.org/index.php?title=Efflux&diff=5223740&oldid=prev 2024-02-22T19:07:49Z

<p>CSV import</p> <p><b>New page</b></p><div>&#039;&#039;&#039;Efflux&#039;&#039;&#039; is a term used in [[biology]] and [[medicine]] to describe the process of active or passive transport of a substance out of a cell or organ. This process is crucial in many biological functions, including the removal of toxins and the regulation of cellular homeostasis.<br /> <br /> == Mechanism ==<br /> <br /> Efflux occurs through [[efflux pump]]s, which are protein-based channels located in the cell membrane. These pumps can transport a variety of substances, including ions, drugs, and metabolic waste products. The transport can be either active, requiring energy in the form of ATP, or passive, relying on the concentration gradient of the substance.<br /> <br /> == Role in Drug Resistance ==<br /> <br /> Efflux pumps play a significant role in [[drug resistance]], particularly in bacteria and cancer cells. These cells can overexpress efflux pumps, leading to the rapid expulsion of drugs and reducing their effectiveness. This mechanism is a major concern in the treatment of many diseases, including [[tuberculosis]], [[malaria]], and [[cancer]].<br /> <br /> == Efflux in Bacteria ==<br /> <br /> In bacteria, efflux pumps are often encoded on [[plasmid]]s, which can be transferred between bacteria, spreading drug resistance. This is a significant problem in the treatment of bacterial infections, as it can lead to the development of [[multidrug-resistant]] strains.<br /> <br /> == Efflux in Cancer Cells ==<br /> <br /> In cancer cells, overexpression of efflux pumps can lead to [[chemotherapy]] resistance. This is a major challenge in cancer treatment, as it can limit the effectiveness of chemotherapy drugs. Research is ongoing to develop inhibitors of efflux pumps to overcome this resistance.<br /> <br /> == See Also ==<br /> <br /> * [[Active transport]]<br /> * [[Passive transport]]<br /> * [[Drug resistance]]<br /> * [[Chemotherapy]]<br /> <br /> == References ==<br /> <br /> &lt;references /&gt;<br /> <br /> {{stub}}<br /> <br /> [[Category:Biology]]<br /> [[Category:Medicine]]<br /> [[Category:Cell biology]]<br /> [[Category:Pharmacology]]<br /> {{dictionary-stub1}}</div>

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