https://wikimd.com/index.php?action=history&feed=atom&title=EXT1 EXT1 - Revision history 2026-04-23T12:28:28Z Revision history for this page on the wiki MediaWiki 1.44.2 https://wikimd.com/index.php?title=EXT1&diff=6504115&oldid=prev Prab: CSV import 2025-03-17T10:08:34Z <p>CSV import</p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 10:08, 17 March 2025</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l23">Line 23:</td> <td colspan="2" class="diff-lineno">Line 23:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{medicine-stub}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{medicine-stub}}</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{No image}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{No image}}</div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">__NOINDEX__</ins></div></td></tr> </table> Prab https://wikimd.com/index.php?title=EXT1&diff=6229975&oldid=prev Prab: CSV import 2025-02-10T16:10:44Z <p>CSV import</p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 16:10, 10 February 2025</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l22">Line 22:</td> <td colspan="2" class="diff-lineno">Line 22:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[[Category:EC 2.8.2]]</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[[Category:EC 2.8.2]]</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{medicine-stub}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{medicine-stub}}</div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">{{No image}}</ins></div></td></tr> </table> Prab https://wikimd.com/index.php?title=EXT1&diff=5383447&oldid=prev Prab: CSV import 2024-03-10T20:55:07Z <p>CSV import</p> <p><b>New page</b></p><div>&#039;&#039;&#039;EXT1&#039;&#039;&#039; is a gene that provides instructions for making an enzyme called exostosin-1. This enzyme is part of a complex that produces heparan sulfate, a long chain of sugar molecules that attach to proteins and form proteoglycans. Proteoglycans are found on the surface of cells and in the extracellular matrix, the lattice of proteins and other molecules outside the cell. Heparan sulfate proteoglycans have many functions, including regulating the growth and division (proliferation) of cells and the process by which cells mature to carry out specific functions (differentiation).<br /> <br /> == Function ==<br /> The [[EXT1]] gene is located on the short (p) arm of chromosome 8 at position 24.1. This gene is active (expressed) in many tissues, but it is not well understood why mutations that eliminate the function of one copy of the EXT1 gene lead specifically to the formation of osteochondromas.<br /> <br /> == Clinical significance ==<br /> Mutations in the EXT1 gene are responsible for multiple osteochondromas, a condition characterized by the development of multiple benign (noncancerous) bone tumors called osteochondromas. The number of osteochondromas and the bones they affect vary greatly among affected individuals. Osteochondromas can cause skeletal abnormalities including deformities and short stature. In some cases, these growths can cause pain and nerve damage.<br /> <br /> == See also ==<br /> * [[EXT2]]<br /> * [[Multiple osteochondromas]]<br /> <br /> == References ==<br /> &lt;references /&gt;<br /> <br /> == External links ==<br /> * [https://ghr.nlm.nih.gov/gene/EXT1 EXT1] at [[Genetics Home Reference]]<br /> * [https://www.ncbi.nlm.nih.gov/gene/2131 EXT1] at [[National Center for Biotechnology Information]]<br /> <br /> [[Category:Genes]]<br /> [[Category:Human proteins]]<br /> [[Category:EC 2.8.2]]<br /> {{medicine-stub}}</div> Prab