https://wikimd.com/index.php?action=history&feed=atom&title=EP300 2026-04-21T23:27:07Z Revision history for this page on the wiki MediaWiki 1.44.2 https://wikimd.com/index.php?title=EP300&diff=6504105&oldid=prev 2025-03-17T10:08:01Z

<p>CSV import</p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 10:08, 17 March 2025</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l34">Line 34:</td> <td colspan="2" class="diff-lineno">Line 34:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{stub}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{stub}}</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{No image}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{No image}}</div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">__NOINDEX__</ins></div></td></tr> </table>

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<p>CSV import</p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 15:58, 10 February 2025</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l33">Line 33:</td> <td colspan="2" class="diff-lineno">Line 33:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{stub}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{stub}}</div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">{{No image}}</ins></div></td></tr> </table>

Prab https://wikimd.com/index.php?title=EP300&diff=5202410&oldid=prev 2024-02-22T01:07:01Z

<p>CSV import</p> <p><b>New page</b></p><div>&#039;&#039;&#039;EP300&#039;&#039;&#039; (also known as E1A binding protein p300) is a gene that encodes the p300 protein in humans. This protein functions as a histone acetyltransferase, which regulates transcription via chromatin remodeling. It is important in cell proliferation and differentiation, and in preventing cell death. Mutations in this gene are associated with a variety of diseases, including cancer.<br /> <br /> == Function ==<br /> <br /> The [[EP300]] gene encodes the p300 protein, a histone acetyltransferase that regulates transcription of numerous genes. This protein is involved in cell proliferation and differentiation, and it also plays a role in preventing cell death. It does this by acetylating histones, which changes the DNA structure and allows transcription factors to access the DNA.<br /> <br /> == Clinical significance ==<br /> <br /> Mutations in the [[EP300]] gene are associated with a variety of diseases. For example, they have been found in some types of cancer, including colorectal, gastric, and breast cancer. These mutations can lead to abnormal cell growth and proliferation, which can contribute to the development of cancer.<br /> <br /> In addition to cancer, mutations in the [[EP300]] gene have also been linked to Rubinstein-Taybi syndrome, a rare genetic disorder characterized by intellectual disability, distinctive facial features, and broad thumbs and first toes.<br /> <br /> == See also ==<br /> <br /> * [[Histone acetyltransferase]]<br /> * [[Transcription (genetics)]]<br /> * [[Rubinstein-Taybi syndrome]]<br /> * [[Cancer]]<br /> <br /> == References ==<br /> <br /> &lt;references /&gt;<br /> <br /> == External links ==<br /> <br /> * [https://www.genecards.org/cgi-bin/carddisp.pl?gene=EP300 GeneCards - EP300]<br /> * [https://ghr.nlm.nih.gov/gene/EP300 Genetics Home Reference - EP300]<br /> <br /> [[Category:Genes]]<br /> [[Category:Proteins]]<br /> [[Category:Oncogenes]]<br /> [[Category:Transcription factors]]<br /> <br /> {{stub}}</div>

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