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	<id>https://wikimd.org/index.php?action=history&amp;feed=atom&amp;title=EGR1</id>
	<title>EGR1 - Revision history</title>
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	<link rel="alternate" type="text/html" href="https://wikimd.org/index.php?title=EGR1&amp;action=history"/>
	<updated>2026-04-25T03:12:14Z</updated>
	<subtitle>Revision history for this page on the wiki</subtitle>
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	<entry>
		<id>https://wikimd.org/index.php?title=EGR1&amp;diff=6504032&amp;oldid=prev</id>
		<title>Prab: CSV import</title>
		<link rel="alternate" type="text/html" href="https://wikimd.org/index.php?title=EGR1&amp;diff=6504032&amp;oldid=prev"/>
		<updated>2025-03-17T10:04:14Z</updated>

		<summary type="html">&lt;p&gt;CSV import&lt;/p&gt;
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				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 10:04, 17 March 2025&lt;/td&gt;
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&lt;/table&gt;</summary>
		<author><name>Prab</name></author>
	</entry>
	<entry>
		<id>https://wikimd.org/index.php?title=EGR1&amp;diff=6229450&amp;oldid=prev</id>
		<title>Prab: CSV import</title>
		<link rel="alternate" type="text/html" href="https://wikimd.org/index.php?title=EGR1&amp;diff=6229450&amp;oldid=prev"/>
		<updated>2025-02-10T15:58:40Z</updated>

		<summary type="html">&lt;p&gt;CSV import&lt;/p&gt;
&lt;table style=&quot;background-color: #fff; color: #202122;&quot; data-mw=&quot;interface&quot;&gt;
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				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 15:58, 10 February 2025&lt;/td&gt;
				&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot; id=&quot;mw-diff-left-l28&quot;&gt;Line 28:&lt;/td&gt;
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&lt;/table&gt;</summary>
		<author><name>Prab</name></author>
	</entry>
	<entry>
		<id>https://wikimd.org/index.php?title=EGR1&amp;diff=5204669&amp;oldid=prev</id>
		<title>Prab: CSV import</title>
		<link rel="alternate" type="text/html" href="https://wikimd.org/index.php?title=EGR1&amp;diff=5204669&amp;oldid=prev"/>
		<updated>2024-02-22T03:09:40Z</updated>

		<summary type="html">&lt;p&gt;CSV import&lt;/p&gt;
&lt;p&gt;&lt;b&gt;New page&lt;/b&gt;&lt;/p&gt;&lt;div&gt;&amp;#039;&amp;#039;&amp;#039;EGR1&amp;#039;&amp;#039;&amp;#039; (Early Growth Response 1) is a [[protein]] that in humans is encoded by the &amp;#039;&amp;#039;EGR1&amp;#039;&amp;#039; [[gene]]. It is also known as Zif268 (zinc finger protein 224), NGFI-A (nerve growth factor-induced protein A), and Krox-24, among other names. EGR1 is a [[transcription factor]] with three [[zinc finger]] domains that bind to DNA and function in the regulation of cellular growth and differentiation.&lt;br /&gt;
&lt;br /&gt;
== Function ==&lt;br /&gt;
EGR1 is a transcription factor that is activated in response to [[growth factors]] and [[stress]]. It is involved in a variety of biological processes, including [[cell proliferation]], [[differentiation]], [[apoptosis]], and [[neoplastic transformation]]. EGR1 can also stimulate expression of target genes, which can influence the growth and development of many types of cells in the body.&lt;br /&gt;
&lt;br /&gt;
== Clinical significance ==&lt;br /&gt;
Alterations in EGR1 expression have been associated with various diseases, including [[cancer]], [[schizophrenia]], [[Alzheimer&amp;#039;s disease]], and [[ischemic injury]]. In cancer, EGR1 can function as a tumor suppressor or an oncogene, depending on the context. In neurological disorders like schizophrenia and Alzheimer&amp;#039;s, changes in EGR1 expression may contribute to disease pathology.&lt;br /&gt;
&lt;br /&gt;
== Research ==&lt;br /&gt;
Research on EGR1 has focused on its role in cell growth and differentiation, as well as its potential as a therapeutic target in cancer and neurological disorders. Studies have also investigated the regulation of EGR1 expression and its interaction with other proteins and genes.&lt;br /&gt;
&lt;br /&gt;
== See also ==&lt;br /&gt;
* [[Zinc finger]]&lt;br /&gt;
* [[Transcription factor]]&lt;br /&gt;
* [[Gene expression]]&lt;br /&gt;
* [[Protein coding gene]]&lt;br /&gt;
&lt;br /&gt;
== References ==&lt;br /&gt;
&amp;lt;references /&amp;gt;&lt;br /&gt;
&lt;br /&gt;
== External links ==&lt;br /&gt;
* [https://www.genecards.org/cgi-bin/carddisp.pl?gene=EGR1 GeneCards - EGR1]&lt;br /&gt;
* [https://www.ncbi.nlm.nih.gov/gene/1958 NCBI - EGR1]&lt;br /&gt;
&lt;br /&gt;
[[Category:Genes]]&lt;br /&gt;
[[Category:Proteins]]&lt;br /&gt;
[[Category:Transcription factors]]&lt;br /&gt;
[[Category:Zinc finger proteins]]&lt;br /&gt;
{{stub}}&lt;/div&gt;</summary>
		<author><name>Prab</name></author>
	</entry>
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