Prab: CSV import

2025-02-13T03:58:14Z

CSV import

← Older revision		Revision as of 03:58, 13 February 2025
Line 1:		Line 1:
	~~'''~~DrugBank~~''' is a comprehensive, high-quality, freely accessible, online database containing information on drugs and drug targets~~. ~~As both a bioinformatics and a cheminformatics resource,~~ DrugBank combines detailed drug (i.e. chemical, pharmacological and pharmaceutical) data with comprehensive drug target (i.e. sequence, structure, and pathway) information. The database is widely used by the drug industry, medicinal chemists, pharmacists, physicians, students and the general public. Its extensive drug and drug-target data has enabled the discovery and repurposing of a number of existing drugs to treat rare and newly identified illnesses.		{{DISPLAYTITLE:DrugBank}}
			[[File:Drugbank_logo.svg\|thumb\|right\|The DrugBank logo]]

	~~== Overview ==~~		'''DrugBank''' is a comprehensive, freely accessible, online database containing information on drugs and drug targets. It is widely used by researchers, educators, and healthcare professionals for its detailed drug data and bioinformatics resources.

	[[~~DrugBank~~]] ~~was first launched in 2006 at the~~ [[~~University~~ of ~~Alberta~~]], and has since been regularly updated and expanded. The database now contains detailed information on over 11,000 drug entries including more than 2,000 FDA-approved small molecule drugs, 1,000 FDA-approved biotech (protein/peptide) drugs, 130 nutraceuticals and over 6,000 experimental drugs.		==Overview==
			DrugBank combines detailed drug data with comprehensive drug target information. It is designed to facilitate drug discovery, drug design, and drug development processes. The database includes information on:
			* [[Chemical structure]]
			* [[Pharmacology]]
			* [[Mechanism of action]]
			* [[Drug interactions]]
			* [[Pharmacokinetics]]
			* [[Pharmacodynamics]]

	== ~~Content~~ ==		==History==
			DrugBank was first released in 2006 by the [[University of Alberta]] in Canada. It was developed as part of a research project led by Dr. David Wishart. Since its inception, DrugBank has undergone several updates and expansions, with the latest version containing information on over 13,000 drug entries.

	~~The [[~~DrugBank~~]] database~~ provides a variety of ~~information about drugs, including~~:		==Features==
			DrugBank provides a variety of features that make it a valuable resource for the scientific community:

	* '''Chemical Information:''' This includes the drug's chemical structure, formula, and molecular weight.		===Drug Data===
	* '''Pharmacological Information:''' This includes the drug's mechanism of action, pharmacodynamics, and ~~pharmacokinetics~~.		DrugBank contains detailed information on both [[approved drugs]] and [[experimental drugs]]. Each drug entry includes data on its chemical properties, [[pharmacological classification]], and [[therapeutic uses]].
	* '''Pharmaceutical Information:''' This includes the drug~~'s dosage, form, and route of administration.~~
	* '''Target Information:''' This includes ~~the drug's known protein targets, their sequence~~, ~~structure~~, and ~~pathway~~.

	== ~~Uses~~ ==		===Target Information===
			The database includes information on drug targets, such as [[proteins]], [[enzymes]], and [[receptors]]. This information is crucial for understanding the [[mechanism of action]] of drugs and for identifying potential [[drug interactions]].

	[[DrugBank~~]] is widely used in the fields~~ of ~~drug discovery, medical research, and education. It is a valuable resource for researchers looking~~ to ~~understand the mechanisms of drug action, predict drug interactions,~~ and ~~explore potential~~ drug ~~repurposing opportunities. In addition, it is used by healthcare professionals and students to learn about the properties and uses of various drugs~~.		===Bioinformatics Tools===
			DrugBank offers a range of bioinformatics tools that allow users to search and analyze drug data. These tools include:
			* [[Chemical similarity search]]
			* [[Substructure search]]
			* [[Pharmacophore search]]

	== ~~Access~~ ==		==Applications==
			DrugBank is used in various fields, including:
			* [[Pharmaceutical research]]
			* [[Clinical research]]
			* [[Education]]
			* [[Healthcare]]

	[[DrugBank~~]] is freely accessible online and can be searched using various criteria~~, ~~including~~ drug ~~name, chemical structure, mechanism of action~~, and ~~target protein. The database also provides links to other relevant resources, such as~~ [[~~PubMed~~]] ~~for scientific literature and [[ClinicalTrials~~.~~gov]] for information on clinical trials involving the~~ drug.		Researchers use DrugBank to identify potential drug candidates, study drug interactions, and explore the [[pharmacogenomics]] of drugs. Educators use it as a teaching tool to explain drug mechanisms and interactions.

	== ~~See Also~~ ==		==Access==
			DrugBank is freely accessible to the public. Users can access the database through its website, where they can search for specific drugs or browse through the database's extensive collection of drug information.

	* [[PharmGKB]]		==Related pages==
	* [[~~KEGG~~]]		* [[Pharmacology]]
	* [[~~ChEMBL~~]]		* [[Drug discovery]]
	* [[~~PubChem~~]]		* [[Bioinformatics]]
	* [[~~ChemSpider~~]]		* [[Pharmacogenomics]]

	~~== References ==~~

	~~<references />~~

			[[Category:Pharmacology databases]]
	[[Category:Bioinformatics databases]]		[[Category:Bioinformatics databases]]
	~~[[Category:Chemical databases]]~~
	~~[[Category:Pharmacology]]~~
	~~[[Category:Medicine]]~~

	~~{{medicine-stub}}~~

Prab: CSV import

2024-03-10T20:31:07Z

CSV import

New page

'''DrugBank''' is a comprehensive, high-quality, freely accessible, online database containing information on drugs and drug targets. As both a bioinformatics and a cheminformatics resource, DrugBank combines detailed drug (i.e. chemical, pharmacological and pharmaceutical) data with comprehensive drug target (i.e. sequence, structure, and pathway) information. The database is widely used by the drug industry, medicinal chemists, pharmacists, physicians, students and the general public. Its extensive drug and drug-target data has enabled the discovery and repurposing of a number of existing drugs to treat rare and newly identified illnesses.

== Overview ==

[[DrugBank]] was first launched in 2006 at the [[University of Alberta]], and has since been regularly updated and expanded. The database now contains detailed information on over 11,000 drug entries including more than 2,000 FDA-approved small molecule drugs, 1,000 FDA-approved biotech (protein/peptide) drugs, 130 nutraceuticals and over 6,000 experimental drugs.

== Content ==

The [[DrugBank]] database provides a variety of information about drugs, including:

* '''Chemical Information:''' This includes the drug's chemical structure, formula, and molecular weight.
* '''Pharmacological Information:''' This includes the drug's mechanism of action, pharmacodynamics, and pharmacokinetics.
* '''Pharmaceutical Information:''' This includes the drug's dosage, form, and route of administration.
* '''Target Information:''' This includes the drug's known protein targets, their sequence, structure, and pathway.

== Uses ==

[[DrugBank]] is widely used in the fields of drug discovery, medical research, and education. It is a valuable resource for researchers looking to understand the mechanisms of drug action, predict drug interactions, and explore potential drug repurposing opportunities. In addition, it is used by healthcare professionals and students to learn about the properties and uses of various drugs.

== Access ==

[[DrugBank]] is freely accessible online and can be searched using various criteria, including drug name, chemical structure, mechanism of action, and target protein. The database also provides links to other relevant resources, such as [[PubMed]] for scientific literature and [[ClinicalTrials.gov]] for information on clinical trials involving the drug.

== See Also ==

* [[PharmGKB]]
* [[KEGG]]
* [[ChEMBL]]
* [[PubChem]]
* [[ChemSpider]]

== References ==

<references />

[[Category:Bioinformatics databases]]
[[Category:Chemical databases]]
[[Category:Pharmacology]]
[[Category:Medicine]]

{{medicine-stub}}

DrugBank - Revision history

Prab: CSV import

Prab: CSV import