https://wikimd.org/index.php?action=history&feed=atom&title=DnaG 2026-04-25T00:32:31Z Revision history for this page on the wiki MediaWiki 1.44.2 https://wikimd.org/index.php?title=DnaG&diff=6322246&oldid=prev 2025-02-18T11:14:54Z

<p>CSV import</p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 11:14, 18 February 2025</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l28">Line 28:</td> <td colspan="2" class="diff-lineno">Line 28:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{stub}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{stub}}</div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">== DnaG ==</ins></div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">&lt;gallery&gt;</ins></div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">File:DNA_replication_en.svg|DNA replication process</ins></div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">File:Oligonucleotide_Synthesis3.jpg|Oligonucleotide synthesis</ins></div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">File:DnaG_Zinc_Binding_Domain.png|DnaG Zinc Binding Domain</ins></div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">File:DnaG_RNA_Polymerase_Domain.png|DnaG RNA Polymerase Domain</ins></div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">File:Helicase_Binding_Domain_of_E._Coli.JPG|Helicase Binding Domain of E. Coli</ins></div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">File:Bacillus_stearothermophilus_DnaG_in_compex_with_the_hexameric_DnaB..JPG|Bacillus stearothermophilus DnaG in complex with the hexameric DnaB</ins></div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">File:Inhibitor_Structures.jpg|Inhibitor Structures</ins></div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">&lt;/gallery&gt;</ins></div></td></tr> </table>

Prab https://wikimd.org/index.php?title=DnaG&diff=5301050&oldid=prev 2024-02-25T22:49:12Z

<p>CSV import</p> <p><b>New page</b></p><div>&#039;&#039;&#039;DnaG&#039;&#039;&#039; is a type of [[RNA primase]] that is essential in the [[DNA replication]] process in [[bacteria]]. It synthesizes short RNA strands (primers) that are used by [[DNA polymerase]] to create the new DNA strand. DnaG is a key component of the [[replisome]], the multi-protein complex that coordinates the replication of DNA.<br /> <br /> == Function ==<br /> <br /> DnaG synthesizes RNA primers that are 10-60 nucleotides long. These primers serve as the starting point for DNA polymerase to begin synthesizing the new DNA strand. DnaG is able to start synthesis at specific points on the DNA template strand, known as [[origin of replication|origins of replication]]. <br /> <br /> == Structure ==<br /> <br /> DnaG is a large protein, typically consisting of several hundred amino acids. It has a complex three-dimensional structure that allows it to bind to the DNA template strand and synthesize the RNA primer. The structure of DnaG includes a catalytic domain that carries out the synthesis of the RNA primer, and a regulatory domain that controls the activity of the enzyme.<br /> <br /> == Role in DNA Replication ==<br /> <br /> During DNA replication, DnaG is recruited to the replisome where it synthesizes the RNA primer. This primer is then extended by DNA polymerase to create the new DNA strand. DnaG is essential for this process, as without the RNA primer, DNA polymerase is unable to start synthesis of the new DNA strand.<br /> <br /> == Clinical Significance ==<br /> <br /> Because of its essential role in DNA replication, DnaG is a potential target for [[antibacterial]] drugs. Inhibitors of DnaG could potentially stop bacterial DNA replication, thereby killing the bacteria.<br /> <br /> == See Also ==<br /> * [[DNA replication]]<br /> * [[RNA primase]]<br /> * [[DNA polymerase]]<br /> * [[Replisome]]<br /> <br /> [[Category:DNA replication]]<br /> [[Category:RNA]]<br /> [[Category:Enzymes]]<br /> <br /> {{stub}}</div>

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