https://wikimd.org/index.php?action=history&feed=atom&title=Dissolve Dissolve - Revision history 2026-05-14T09:21:04Z Revision history for this page on the wiki MediaWiki 1.44.2 https://wikimd.org/index.php?title=Dissolve&diff=6528021&oldid=prev Prab at 17:20, 18 March 2025 2025-03-18T17:20:03Z <p></p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 17:20, 18 March 2025</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l28">Line 28:</td> <td colspan="2" class="diff-lineno">Line 28:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; 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color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 14:59, 10 February 2025</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l26">Line 26:</td> <td colspan="2" class="diff-lineno">Line 26:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; 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In the context of pharmacy, it is particularly relevant to the process of drug delivery, as the rate at which a drug dissolves can affect its [[Pharmacokinetics|pharmacokinetics]] and [[Pharmacodynamics|pharmacodynamics]].<br /> <br /> == Process of Dissolution ==<br /> <br /> Dissolution occurs when a solute interacts with a solvent to form a solution. This process is influenced by several factors, including the [[Temperature|temperature]] of the solvent, the [[Surface area|surface area]] of the solute, and the presence of stirring or agitation. <br /> <br /> In the pharmaceutical industry, dissolution testing is a standard practice used to predict the in vivo performance of oral dosage forms such as tablets and capsules. The rate of dissolution (dissolution rate) is defined as the amount of drug substance that goes into solution per unit time under standardized conditions of liquid/solid interface, temperature, and solvent composition.<br /> <br /> == Factors Affecting Dissolution ==<br /> <br /> Several factors can affect the rate of dissolution, including:<br /> <br /> * &#039;&#039;&#039;[[Particle size]]&#039;&#039;&#039;: Smaller particles have a larger surface area and dissolve more quickly.<br /> * &#039;&#039;&#039;[[Temperature]]&#039;&#039;&#039;: Higher temperatures generally increase the rate of dissolution due to increased kinetic energy of the molecules.<br /> * &#039;&#039;&#039;[[Solvent]] properties&#039;&#039;&#039;: The chemical nature of the solvent can greatly affect how quickly a solute dissolves.<br /> * &#039;&#039;&#039;[[Pressure]]&#039;&#039;&#039;: Increased pressure can increase the rate of dissolution, although this effect is generally less significant than the effects of temperature and solvent properties.<br /> <br /> == Dissolution in Pharmacy ==<br /> <br /> In the field of pharmacy, the dissolution of a drug is a critical factor in its effectiveness. The rate at which a drug dissolves can affect how quickly it is absorbed into the body, and therefore how quickly it takes effect. This is particularly important for drugs that are intended to act quickly, such as pain relievers.<br /> <br /> [[Category:Chemistry]]<br /> [[Category:Pharmacy]]<br /> [[Category:Pharmacokinetics]]<br /> [[Category:Pharmacodynamics]]<br /> <br /> {{stub}}</div> Prab