https://wikimd.org/index.php?action=history&feed=atom&title=Dienestrol 2026-04-27T01:19:59Z Revision history for this page on the wiki MediaWiki 1.44.2 https://wikimd.org/index.php?title=Dienestrol&diff=5369146&oldid=prev 2024-03-06T04:56:51Z

<p>CSV import</p> <p><b>New page</b></p><div>[[File:Dienestrol.png|thumb|{{PAGENAME}}]]&lt;br&gt;&#039;&#039;&#039;Dienestrol&#039;&#039;&#039; is a synthetic, non-steroidal [[estrogen]] that was first synthesized in 1939. It is used in medicine for its estrogenic effects, such as in the treatment of menopausal symptoms and in hormone replacement therapy. <br /> <br /> == History ==<br /> [[Dienestrol]] was first synthesized in 1939, shortly after the discovery of the estrogenic properties of [[stilbestrol]]. It was introduced for medical use in the 1940s, around the same time as [[diethylstilbestrol]] (DES), and was marketed under a variety of brand names including &#039;&#039;Cycladiene&#039;&#039;, &#039;&#039;Dienoestrol&#039;&#039;, &#039;&#039;Dienoestrol Ortho&#039;&#039;, &#039;&#039;Sexadiene&#039;&#039;, and &#039;&#039;Follormon&#039;&#039;.<br /> <br /> == Medical uses ==<br /> Dienestrol is used in medicine for its estrogenic effects. It is used in the treatment of [[menopausal symptoms]], such as hot flashes and vaginal dryness. It is also used in [[hormone replacement therapy]] (HRT) for women who have undergone menopause. In addition, it has been used to treat prostate cancer and breast cancer, although it is not commonly used for these purposes today.<br /> <br /> == Pharmacology ==<br /> Dienestrol is a synthetic, non-steroidal estrogen, which means it is not derived from natural sources and does not have a steroid structure. It is a type of [[phenolic compound]], specifically a [[stilbene derivative]]. It works by binding to and activating the [[estrogen receptor]], which is found in various tissues throughout the body.<br /> <br /> == Side effects ==<br /> Like other estrogens, dienestrol can have a number of side effects. These can include nausea, vomiting, bloating, breast tenderness, headache, and changes in menstrual periods. More serious side effects can include blood clots, stroke, and an increased risk of certain types of cancer.<br /> <br /> == See also ==<br /> * [[Estrogen]]<br /> * [[Hormone replacement therapy]]<br /> * [[Menopause]]<br /> * [[Phenolic compound]]<br /> * [[Stilbene derivative]]<br /> <br /> [[Category:Estrogens]]<br /> [[Category:Phenolic compounds]]<br /> [[Category:Stilbene derivatives]]<br /> [[Category:Hormone replacement therapy]]<br /> [[Category:Menopause]]<br /> {{Pharmacology-stub}}</div>

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