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← Older revision		Revision as of 11:17, 18 February 2025
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	[[Category:Biochemistry]]		[[Category:Biochemistry]]
	[[Category:Metabolism]]		[[Category:Metabolism]]
			<gallery caption="Dehydrogenase">
			File:Sulcatone_reductase_reaction.PNG\|Sulcatone reductase reaction
			File:Alcohol_dehydrogenase.png\|Alcohol dehydrogenase
			File:Krebs_cycle_6_succinate_to_fumarate.svg\|Krebs cycle: succinate to fumarate
			File:Vanillyl-alcohol_oxidase_reaction.PNG\|Vanillyl-alcohol oxidase reaction
			File:NAD+_phys_alt.svg\|NAD+
			File:NADP+_phys_alt.svg\|NADP+
			File:FAD.svg\|FAD
			File:Aldehyde_dehydrogenase_mechanism.png\|Aldehyde dehydrogenase mechanism
			</gallery>

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2024-02-22T15:16:31Z

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'''Dehydrogenase''' is a type of [[enzyme]] that catalyzes the removal of [[hydrogen]] atoms from a particular molecule, particularly in the context of a [[biochemical]] reaction. This process is known as [[oxidation]].

== Function ==

Dehydrogenases play a crucial role in the metabolism of [[carbohydrates]], [[lipids]], and [[proteins]]. They are involved in various metabolic pathways, including [[glycolysis]], the [[citric acid cycle]], and [[electron transport chain]].

== Types of Dehydrogenases ==

There are several types of dehydrogenases, each with a specific function. Some of the most common types include:

* '''[[Alcohol dehydrogenase]]''' - This enzyme is responsible for the breakdown of alcohols, including ethanol found in alcoholic beverages.
* '''[[Lactate dehydrogenase]]''' - This enzyme is involved in the conversion of lactate to pyruvate, an important step in the metabolic pathway.
* '''[[Glucose-6-phosphate dehydrogenase]]''' - This enzyme plays a key role in the pentose phosphate pathway, a process that generates NADPH and pentoses.
* '''[[Pyruvate dehydrogenase]]''' - This enzyme is crucial in the metabolic pathway, converting pyruvate into acetyl-CoA, which is then used in the citric acid cycle.

== Clinical Significance ==

Dehydrogenase enzymes are often used as [[biomarkers]] in the diagnosis and monitoring of various diseases. For instance, elevated levels of lactate dehydrogenase can indicate tissue damage or disease. Similarly, deficiencies in glucose-6-phosphate dehydrogenase can lead to [[hemolytic anemia]].

== See Also ==

* [[Enzyme]]
* [[Metabolism]]
* [[Oxidation]]
* [[Biochemical reaction]]

== References ==

<references />

{{stub}}

[[Category:Enzymes]]
[[Category:Biochemistry]]
[[Category:Metabolism]]

Dehydrogenase - Revision history

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