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	<id>https://wikimd.org/index.php?action=history&amp;feed=atom&amp;title=Dark_therapy</id>
	<title>Dark therapy - Revision history</title>
	<link rel="self" type="application/atom+xml" href="https://wikimd.org/index.php?action=history&amp;feed=atom&amp;title=Dark_therapy"/>
	<link rel="alternate" type="text/html" href="https://wikimd.org/index.php?title=Dark_therapy&amp;action=history"/>
	<updated>2026-04-27T01:25:22Z</updated>
	<subtitle>Revision history for this page on the wiki</subtitle>
	<generator>MediaWiki 1.44.2</generator>
	<entry>
		<id>https://wikimd.org/index.php?title=Dark_therapy&amp;diff=6531700&amp;oldid=prev</id>
		<title>Prab at 01:31, 19 March 2025</title>
		<link rel="alternate" type="text/html" href="https://wikimd.org/index.php?title=Dark_therapy&amp;diff=6531700&amp;oldid=prev"/>
		<updated>2025-03-19T01:31:23Z</updated>

		<summary type="html">&lt;p&gt;&lt;/p&gt;
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				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 01:31, 19 March 2025&lt;/td&gt;
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&lt;/table&gt;</summary>
		<author><name>Prab</name></author>
	</entry>
	<entry>
		<id>https://wikimd.org/index.php?title=Dark_therapy&amp;diff=6503357&amp;oldid=prev</id>
		<title>Prab: CSV import</title>
		<link rel="alternate" type="text/html" href="https://wikimd.org/index.php?title=Dark_therapy&amp;diff=6503357&amp;oldid=prev"/>
		<updated>2025-03-17T09:23:38Z</updated>

		<summary type="html">&lt;p&gt;CSV import&lt;/p&gt;
&lt;table style=&quot;background-color: #fff; color: #202122;&quot; data-mw=&quot;interface&quot;&gt;
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				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;← Older revision&lt;/td&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 09:23, 17 March 2025&lt;/td&gt;
				&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot; id=&quot;mw-diff-left-l51&quot;&gt;Line 51:&lt;/td&gt;
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&lt;/table&gt;</summary>
		<author><name>Prab</name></author>
	</entry>
	<entry>
		<id>https://wikimd.org/index.php?title=Dark_therapy&amp;diff=6223891&amp;oldid=prev</id>
		<title>Prab: CSV import</title>
		<link rel="alternate" type="text/html" href="https://wikimd.org/index.php?title=Dark_therapy&amp;diff=6223891&amp;oldid=prev"/>
		<updated>2025-02-10T13:28:30Z</updated>

		<summary type="html">&lt;p&gt;CSV import&lt;/p&gt;
&lt;table style=&quot;background-color: #fff; color: #202122;&quot; data-mw=&quot;interface&quot;&gt;
				&lt;col class=&quot;diff-marker&quot; /&gt;
				&lt;col class=&quot;diff-content&quot; /&gt;
				&lt;col class=&quot;diff-marker&quot; /&gt;
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				&lt;tr class=&quot;diff-title&quot; lang=&quot;en&quot;&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;← Older revision&lt;/td&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 13:28, 10 February 2025&lt;/td&gt;
				&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot; id=&quot;mw-diff-left-l49&quot;&gt;Line 49:&lt;/td&gt;
&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Line 49:&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;[[Category:Light therapy]]&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;[[Category:Light therapy]]&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;[[Category:Treatment of bipolar disorder]]&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;[[Category:Treatment of bipolar disorder]]&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;{{No image}}&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;{{No image}}&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;{{No image}}&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;/table&gt;</summary>
		<author><name>Prab</name></author>
	</entry>
	<entry>
		<id>https://wikimd.org/index.php?title=Dark_therapy&amp;diff=6223602&amp;oldid=prev</id>
		<title>Prab: CSV import</title>
		<link rel="alternate" type="text/html" href="https://wikimd.org/index.php?title=Dark_therapy&amp;diff=6223602&amp;oldid=prev"/>
		<updated>2025-02-10T13:18:51Z</updated>

		<summary type="html">&lt;p&gt;CSV import&lt;/p&gt;
&lt;table style=&quot;background-color: #fff; color: #202122;&quot; data-mw=&quot;interface&quot;&gt;
				&lt;col class=&quot;diff-marker&quot; /&gt;
				&lt;col class=&quot;diff-content&quot; /&gt;
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				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;← Older revision&lt;/td&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 13:18, 10 February 2025&lt;/td&gt;
				&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot; id=&quot;mw-diff-left-l49&quot;&gt;Line 49:&lt;/td&gt;
&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Line 49:&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;[[Category:Light therapy]]&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;[[Category:Light therapy]]&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;[[Category:Treatment of bipolar disorder]]&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;[[Category:Treatment of bipolar disorder]]&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;{{No image}}&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;/table&gt;</summary>
		<author><name>Prab</name></author>
	</entry>
	<entry>
		<id>https://wikimd.org/index.php?title=Dark_therapy&amp;diff=4968353&amp;oldid=prev</id>
		<title>Prab at 16:22, 16 September 2023</title>
		<link rel="alternate" type="text/html" href="https://wikimd.org/index.php?title=Dark_therapy&amp;diff=4968353&amp;oldid=prev"/>
		<updated>2023-09-16T16:22:25Z</updated>

		<summary type="html">&lt;p&gt;&lt;/p&gt;
&lt;p&gt;&lt;b&gt;New page&lt;/b&gt;&lt;/p&gt;&lt;div&gt;&amp;#039;&amp;#039;&amp;#039;Dark therapy&amp;#039;&amp;#039;&amp;#039;, also colloquially known as &amp;#039;&amp;#039;&amp;#039;scototherapy&amp;#039;&amp;#039;&amp;#039; or &amp;#039;&amp;#039;&amp;#039;light restriction&amp;#039;&amp;#039;&amp;#039;, is a treatment approach that entails the meticulous elimination of light exposure for durations spanning six to sixteen hours daily. This is often harmoniously synchronized with a consistent sleep schedule. The foundational premise rests on the manipulation of circadian rhythms, with notable effects on an array of hormones and neurotransmitters.&lt;br /&gt;
&lt;br /&gt;
=== Mechanism and Clinical Pharmacology ===&lt;br /&gt;
&lt;br /&gt;
Central to the efficacy of dark therapy is the hormone &amp;#039;&amp;#039;&amp;#039;melatonin&amp;#039;&amp;#039;&amp;#039;, synthesized by the pineal gland in the absence of light. Controlled light-dark cycles, surprisingly, even in certain blind individuals, exhibit melatonin production. This sheds light on the role of &amp;#039;&amp;#039;&amp;#039;melanopsin&amp;#039;&amp;#039;&amp;#039; in circadian rhythm regulation among humans.&lt;br /&gt;
&lt;br /&gt;
=== Applications in Bipolar Disorder ===&lt;br /&gt;
&lt;br /&gt;
While initial studies remain limited in scale, pioneering research from Hospital San Raffaele in Milan posits that controlling environmental stimuli and utilizing chronobiological interventions could supplement the therapeutic approach for acute mania. Subsequent studies delving into 24-hour and 48-hour biological clocks have augmented our understanding.&lt;br /&gt;
&lt;br /&gt;
=== Role in Circadian Rhythm Disorders ===&lt;br /&gt;
&lt;br /&gt;
Disorders such as the &amp;#039;&amp;#039;&amp;#039;delayed sleep phase disorder&amp;#039;&amp;#039;&amp;#039; and the &amp;#039;&amp;#039;&amp;#039;non-24-hour sleep-wake disorder&amp;#039;&amp;#039;&amp;#039; have traditionally been managed with light therapy during awakening to inhibit melatonin. Adjunctively, light restriction and external melatonin supplementation can help in advancing the sleep phase.&lt;br /&gt;
&lt;br /&gt;
=== Other Therapeutic Implications ===&lt;br /&gt;
&lt;br /&gt;
* &amp;#039;&amp;#039;&amp;#039;Seasonal Conditions&amp;#039;&amp;#039;&amp;#039;: There are disorders with seasonal symptom exacerbations, like nocturnal asthma, associated depression, migraine, dyssomnia, chronic fatigue syndrome, and fibromyalgia, where dark therapy (often combined with bright light therapy) has been explored.&lt;br /&gt;
* &amp;#039;&amp;#039;&amp;#039;Melatonin&amp;#039;s Multifaceted Role&amp;#039;&amp;#039;&amp;#039;: Beyond its role in sleep, melatonin contributes to cancer prevention, fortifies bone metabolism, bolsters immune function, and aids detoxification. Furthermore, its antioxidant properties, hypertensive reduction capabilities, and sleep-promotion in insomniac individuals make it a molecule of immense therapeutic interest.&lt;br /&gt;
&lt;br /&gt;
=== Virtual Darkness: A Modern Approach ===&lt;br /&gt;
&lt;br /&gt;
In the age of digitalization, the concept of darkness has been redefined. Amber lenses, capable of filtering blue spectrum light, emulate the physiological effects of actual darkness, preserving nocturnal melatonin levels, even in environments that traditionally inhibit melatonin synthesis.&lt;br /&gt;
&lt;br /&gt;
=== Constraints and Considerations ===&lt;br /&gt;
&lt;br /&gt;
Implementing dark therapy necessitates certain conditions:&lt;br /&gt;
&lt;br /&gt;
Ensuring an environment that&amp;#039;s devoid of light. Common light sources can potentially disrupt the treatment&amp;#039;s efficacy.&lt;br /&gt;
Timing is paramount. The dark hours need synchronization with the individual&amp;#039;s circadian rhythm for optimal benefits.&lt;br /&gt;
&lt;br /&gt;
=== Conclusion ===&lt;br /&gt;
&lt;br /&gt;
Dark therapy, although a nascent domain, presents promising avenues in the vast terrain of therapeutic interventions.&lt;br /&gt;
==See also==&lt;br /&gt;
* [[Clinical depression]]&lt;br /&gt;
* [[Light therapy]]&lt;br /&gt;
* [[Migraine]]&lt;br /&gt;
* [[Sleep hygiene]]&lt;br /&gt;
* [[Sunglasses]]&lt;br /&gt;
==External links==&lt;br /&gt;
* [http://www.photoperiodeffect.com/ PhotoperiodEffect]&lt;br /&gt;
{{sleep}}&lt;br /&gt;
{{stub}}&lt;br /&gt;
{{DEFAULTSORT:Dark Therapy}}&lt;br /&gt;
[[Category:Circadian rhythm]]&lt;br /&gt;
[[Category:Mental health]]&lt;br /&gt;
[[Category:Sleep]]&lt;br /&gt;
[[Category:Therapy]]&lt;br /&gt;
[[Category:Light therapy]]&lt;br /&gt;
[[Category:Treatment of bipolar disorder]]&lt;/div&gt;</summary>
		<author><name>Prab</name></author>
	</entry>
</feed>