Prab: CSV import

2025-02-20T00:56:17Z

CSV import

← Older revision		Revision as of 00:56, 20 February 2025
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			File:Cyproterone.svg\|Cyproterone
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Deepika vegiraju at 07:38, 17 July 2023

2023-07-17T07:38:13Z

New page

{{intro}}
Cyproterone is a steroidal antiandrogen that has been used in the [[treatment]] of prostate cancer in many countries of the world, but not in the United States.

{{livtox}}
Cyproterone therapy can be associated with serum enzyme elevations during therapy and has been linked to many instances of clinically apparent acute [[liver injury]], some of which were fatal.

{{moa}}
Cyproterone (sye pro' ter one) is a synthetic steroidal antiandrogen that has been used to treat prostate cancer in many countries of the world, but was never approved for this use in the United States. Cyproterone is a derivative of hydroxyprogesterone and has mild progesterone-like effects. Its mechanism of action, however, appears to be via blocking of the androgen receptor. Alone or when combined with other agents, cyproterone has been found to be palliative in patients with advanced prostate cancer. Cyproterone has also been evaluated for hormonally sensitive benign conditions such as endometriosis, precocious puberty and infertility, but has not been formally recommended for these uses. Because of its potential to cause [[liver injury]] and its inferior efficacy in comparison to other antiandrogens, cyproterone is now rarely used.

{{dose}}
The typical dose regimen is 50 to 100 mg two to three times daily, often in combination with a gonadotropin releasing hormone agonist such as leuprolide, goserelin, histrelin or triptorelin.

{{se}}
Common [[side effects]] include hot flashes, sexual dysfunction, [[nausea]], [[diarrhea]], weight change and fluid retention.

{{cancer drugs}}
{{coststubd}}

Cyproterone - Revision history

Prab: CSV import

Deepika vegiraju at 07:38, 17 July 2023