Cuffitis - Revision history

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← Older revision		Revision as of 21:25, 20 February 2025
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	[[Category:Inflammatory bowel disease]]		[[Category:Inflammatory bowel disease]]
	[[Category:Surgical complications]]		[[Category:Surgical complications]]
			<gallery>
			File:Ileal_pouch-anal_anastomosis.svg\|Cuffitis
			</gallery>

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	{{Infobox medical condition ~~(new)~~
	\| name = ~~{{PAGENAME}}~~		{{Infobox medical condition
	~~\| synonyms =~~		\| name = Cuffitis
	\| image = ~~File:Ileal pouch~~-~~anal anastomosis.svg~~		\| image = <!-- Image removed -->
	~~\| alt =~~		\| caption = <!-- Caption removed -->
	\| caption = ~~Different regions of Ileal pouch~~-~~anal anastomosis~~		\| field = [[Gastroenterology]]
	~~\| pronounce =~~		\| symptoms = [[Rectal bleeding]], [[abdominal pain]], [[diarrhea]]
	\| field = [[~~General surgery~~]]		\| complications = [[Pouch failure]]
	\| symptoms =		\| onset = Post-surgical
	\| complications =		\| duration = Chronic
	\| onset =		\| causes = [[Inflammation]] of the [[rectal cuff]]
	\| duration =		\| risks = [[Ulcerative colitis]], [[Familial adenomatous polyposis]]
	~~\| types~~ =		\| diagnosis = [[Endoscopy]], [[Biopsy]]
	\| causes =		\| treatment = [[Topical therapy]], [[Oral medication]]
	\| risks =		\| frequency = Common in patients with [[ileal pouch-anal anastomosis]]
	\| diagnosis =
	~~\| differential =~~
	~~\| prevention~~ =
	\| treatment =
	\| medication =
	~~\| prognosis =~~
	\| frequency =
	~~\| deaths~~ =
	}}		}}

	'''Cuffitis''' is ~~inflammation at~~ the ~~anal transition zone or “cuff” created as a result of~~ [[~~Ileo-anal pouch\|~~ileal pouch-anal anastomosis]] (IPAA)~~.<ref name=":0">{{Cite web\|url=http://my.clevelandclinic.org/services/digestive_diseases/diseases-conditions/hic-pouchitis\|title=Pouchitis: Causes~~, ~~Symptoms & Treatment {{!}} Cleveland Clinic\|website=my.clevelandclinic.org\|access-date=2016-12-12}}</ref> It is considered~~ a ~~variant form of~~ [[ulcerative colitis]] that occurs in the rectal cuff.<ref name=":1">{{Cite journal\|last=Shen\|first=Bo\|date=2016-12-12\|title=Diagnosis and Management of Postoperative Ileal Pouch Disorders\|journal=Clinics in Colon and Rectal Surgery\|volume=23\|issue=4\|pages=259–268\|doi=10.1055/s-0030-1268252\|issn=1531-0043\|pmc=3134805\|pmid=22131896}}</ref> Cuffitis is a common complication of IPAA, particularly when a stapled [[Surgical anastomosis\|anastomosis]] without [[~~mucosectomy~~]] ~~procedure has been used~~.~~<ref name=":1" />~~		'''Cuffitis''' is an inflammatory condition affecting the [[rectal cuff]] in patients who have undergone [[ileal pouch-anal anastomosis]] (IPAA), a surgical procedure often performed for individuals with [[ulcerative colitis]] or [[familial adenomatous polyposis]].

	== ~~Signs and symptoms~~ ==		== Symptoms ==
	~~Symptoms~~ of ~~cuffitis mimic~~ those of [[pouchitis]]~~.<ref name=":1" /> In addition, patients with cuffitis often present with small volume bloody bowel movements.<ref name=":1" /> Often~~, ~~cuffitis can produce the appearance~~ of ~~bright red blood on tissue~~.~~<ref name=":0" />~~		Patients with cuffitis typically experience symptoms such as [[rectal bleeding]], [[abdominal pain]], and [[diarrhea]]. These symptoms can significantly impact the quality of life and may resemble those of [[pouchitis]], another complication of IPAA.

	==~~= Complications =~~==		== Causes ==
	~~Surgery-associated~~ [[~~ischemia~~]] ~~may contribute~~ inflammation at the ~~anal transitional zone~~.~~<ref name=":1" />~~		Cuffitis is caused by [[inflammation]] of the [[rectal cuff]], which is the small segment of [[rectum]] left after the removal of the [[colon]] and [[rectum]] during IPAA. The inflammation can be due to residual [[ulcerative colitis]] in the cuff or other inflammatory processes.

	~~Patients whose~~ cuffitis is ~~refractory to mesalamine and/or corticosteroids should be evaluated for other disease in the cuff area, such as~~ [[~~Anal fistula\|fistula~~]] ~~or anastomotic leaks.<ref name=":1" /> Cuffitis that is refractory to medication can also be~~ a ~~sign~~ of [[~~Crohn's disease~~]] of ~~the pouch~~.~~<ref name=":1" />~~		== Diagnosis ==
			The diagnosis of cuffitis is typically made through [[endoscopy]], where a visual examination of the rectal cuff is performed. A [[biopsy]] may also be taken to confirm the presence of inflammation and to rule out other conditions.

	~~Chronic~~ cuffitis ~~can also contribute to the development of anastomotic~~ [[~~Stricture~~ (~~medicine~~)~~\|stricture~~]].~~<ref name=":1" />~~		== Treatment ==
			Treatment for cuffitis often involves [[topical therapy]] with [[steroid]] or [[5-aminosalicylic acid]] (5-ASA) suppositories or enemas. In some cases, [[oral medication]] may be prescribed to manage the inflammation. It is important to differentiate cuffitis from [[pouchitis]] as the treatment strategies may differ.
	~~Cuffitis that is refractory, Crohn's-related, or~~ is ~~associated with surgical complications can contribute~~ to ~~pouch failure~~.~~<ref name=":1" />~~

	== ~~Diagnosis~~ ==		== Complications ==
	~~Definitive diagnose of~~ cuffitis ~~is obtained by~~ [[~~endoscopy~~]].~~<ref name=":1" />~~		If left untreated, cuffitis can lead to complications such as [[pouch failure]], which may necessitate further surgical intervention.

	== ~~Treatment~~ ==		== See also ==
	~~Cuffitis is treated with~~ [[~~Mesalazine\|mesalamine~~]] ~~suppositories or topical application of~~ [[~~lidocaine~~]] or [[~~corticosteroid~~]] ~~medications.<ref name=":1" />~~ [[~~Systemic administration\|Systemic medications~~]] ~~are rarely used.<ref name=":1" />~~		* [[Pouchitis]]
			* [[Ulcerative colitis]]
			* [[Familial adenomatous polyposis]]
			* [[Ileal pouch-anal anastomosis]]

	== References ==		== References ==
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	== External links ==		== External links ==
	~~{{Medical resources~~		* [https://www.wikimd.com/wiki/Cuffitis Cuffitis on WikiMD]
	~~\| ICD10 = <!--{{ICD10\|Xxx.x}}-->~~
	~~\| ICD9 = <!--{{ICD9\|xxx}}-->~~
	~~\| ICDO =~~
	~~\| OMIM =~~
	~~\| DiseasesDB =~~
	~~\| MedlinePlus =~~
	~~\| eMedicineSubj =~~
	~~\| eMedicineTopic =~~
	~~\| MeSH =~~
	~~\| GeneReviewsNBK =~~
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	}}
	[[~~Category~~:~~Gastrointestinal tract disorders]]~~
	~~[[Category:Complications of surgical and medical care]]~~
	~~[[Category:Inflammations]~~]


	{{disease~~-stub}}~~		[[Category:Gastroenterology]]
	~~{{dictionary-stub1}}~~		[[Category:Inflammatory bowel disease]]
			[[Category:Surgical complications]]

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2024-02-21T04:52:14Z

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New page

{{Infobox medical condition (new)
| name = {{PAGENAME}}
| synonyms =
| image = File:Ileal pouch-anal anastomosis.svg
| alt =
| caption = Different regions of Ileal pouch-anal anastomosis
| pronounce =
| field = [[General surgery]]
| symptoms =
| complications =
| onset =
| duration =
| types =
| causes =
| risks =
| diagnosis =
| differential =
| prevention =
| treatment =
| medication =
| prognosis =
| frequency =
| deaths =
}}

'''Cuffitis''' is inflammation at the anal transition zone or “cuff” created as a result of [[Ileo-anal pouch|ileal pouch-anal anastomosis]] (IPAA).<ref name=":0">{{Cite web|url=http://my.clevelandclinic.org/services/digestive_diseases/diseases-conditions/hic-pouchitis|title=Pouchitis: Causes, Symptoms & Treatment {{!}} Cleveland Clinic|website=my.clevelandclinic.org|access-date=2016-12-12}}</ref> It is considered a variant form of [[ulcerative colitis]] that occurs in the rectal cuff.<ref name=":1">{{Cite journal|last=Shen|first=Bo|date=2016-12-12|title=Diagnosis and Management of Postoperative Ileal Pouch Disorders|journal=Clinics in Colon and Rectal Surgery|volume=23|issue=4|pages=259–268|doi=10.1055/s-0030-1268252|issn=1531-0043|pmc=3134805|pmid=22131896}}</ref> Cuffitis is a common complication of IPAA, particularly when a stapled [[Surgical anastomosis|anastomosis]] without [[mucosectomy]] procedure has been used.<ref name=":1" />

== Signs and symptoms ==
Symptoms of cuffitis mimic those of [[pouchitis]].<ref name=":1" /> In addition, patients with cuffitis often present with small volume bloody bowel movements.<ref name=":1" /> Often, cuffitis can produce the appearance of bright red blood on tissue.<ref name=":0" />

=== Complications ===
Surgery-associated [[ischemia]] may contribute inflammation at the anal transitional zone.<ref name=":1" />

Patients whose cuffitis is refractory to mesalamine and/or corticosteroids should be evaluated for other disease in the cuff area, such as [[Anal fistula|fistula]] or anastomotic leaks.<ref name=":1" /> Cuffitis that is refractory to medication can also be a sign of [[Crohn's disease]] of the pouch.<ref name=":1" />

Chronic cuffitis can also contribute to the development of anastomotic [[Stricture (medicine)|stricture]].<ref name=":1" />

Cuffitis that is refractory, Crohn's-related, or is associated with surgical complications can contribute to pouch failure.<ref name=":1" />

== Diagnosis ==
Definitive diagnose of cuffitis is obtained by [[endoscopy]].<ref name=":1" />

== Treatment ==
Cuffitis is treated with [[Mesalazine|mesalamine]] suppositories or topical application of [[lidocaine]] or [[corticosteroid]] medications.<ref name=":1" /> [[Systemic administration|Systemic medications]] are rarely used.<ref name=":1" />

== References ==
{{Reflist}}

== External links ==
{{Medical resources
| ICD10 = 
| ICD9 = 
| ICDO =
| OMIM =
| DiseasesDB =
| MedlinePlus =
| eMedicineSubj =
| eMedicineTopic =
| MeSH =
| GeneReviewsNBK =
| GeneReviewsName =
| Orphanet =
}}
[[Category:Gastrointestinal tract disorders]]
[[Category:Complications of surgical and medical care]]
[[Category:Inflammations]]

{{disease-stub}}
{{dictionary-stub1}}