https://wikimd.com/index.php?action=history&feed=atom&title=Corticosteroid 2026-04-23T17:29:16Z Revision history for this page on the wiki MediaWiki 1.44.2 https://wikimd.com/index.php?title=Corticosteroid&diff=4962006&oldid=prev 2023-05-17T02:16:54Z

<p></p> <p><b>New page</b></p><div>&#039;&#039;&#039;Corticosteroids&#039;&#039;&#039; are a class of [[steroid hormone]]s made in the [[adrenal gland|adrenal cortex]] of [[vertebrates]]. The term is also used for the synthetic analogues of these hormones.<br /> [[File:Cortisol3.svg|thumb|Cortisol3]]<br /> ==Overview==<br /> The two main classes of corticosteroids are [[glucocorticoid]]s and [[mineralocorticoid]]s. They play a crucial role in a wide range of [[physiology|physiological]] processes:<br /> <br /> [[stress (medicine)|stress response]]<br /> [[immune system|immune response]]<br /> regulation of [[inflammation]]<br /> [[carbohydrate]] [[metabolism]]<br /> [[protein]] [[catabolism]]<br /> blood [[electrolyte]] levels<br /> behavior&lt;ref name=&quot;:0&quot;&gt;{{Cite book|title = Endocrinology: An Integrated Approach|last = Nussey|first = S.|publisher = Oxford: BIOS Scientific Publishers|year = 2001|isbn = |location = |pages = |url = https://www.ncbi.nlm.nih.gov/books/NBK26/|last2 = Whitehead|first2 = S.}}&lt;/ref&gt;<br /> ==Synthesis and regulation==<br /> Corticosteroids are synthesized in the adrenal cortex, which is part of the [[adrenal gland]]. The production and release of these hormones are regulated by the [[hypothalamus]] and the [[pituitary gland]] through the [[hypothalamic-pituitary-adrenal axis]] (HPA axis).<br /> <br /> ==Clinical uses==<br /> Corticosteroids have a variety of clinical applications due to their anti-inflammatory, immunosuppressive, and hormone replacement properties. They are used to treat conditions such as:<br /> * [[Asthma]]<br /> * [[Autoimmune diseases]]<br /> * [[Inflammatory bowel disease]]<br /> * [[Allergic reactions]]<br /> * [[Rheumatoid arthritis]]<br /> * [[Adrenal insufficiency]]<br /> ==Side effects and precautions==<br /> Long-term use of corticosteroids can lead to side effects, including:<br /> * [[Cushing&#039;s syndrome]]<br /> * [[Osteoporosis]]<br /> * [[Hyperglycemia]]<br /> * [[Glaucoma]]<br /> * [[Muscle weakness]]<br /> * [[Immunosuppression]]<br /> To minimize these risks, corticosteroids are often prescribed at the lowest effective dose for the shortest duration necessary.<br /> {{corticosteroids}}<br /> {{stub}}<br /> [[Category:Steroid hormones]]<br /> [[Category:Corticosteroids]]<br /> [[Category:Endocrine system]]<br /> [[Category:Immunosuppressants]]<br /> [[Category:Anti-inflammatory agents]]<br /> [[Category:Steroid hormones]]</div>

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