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<p>CSV import</p> <p><b>New page</b></p><div>[[file:Cortical_Columns.jpg|thumb|left]] &#039;&#039;&#039;Cortical column&#039;&#039;&#039;<br /> <br /> A &#039;&#039;&#039;cortical column&#039;&#039;&#039; is a group of [[neurons]] in the [[cerebral cortex]] of the [[brain]] that can be considered a basic functional unit of the [[cortex]]. These columns are arranged perpendicularly to the surface of the cortex and are thought to be involved in processing specific types of information.<br /> <br /> ==Structure==<br /> Cortical columns are composed of several layers of neurons, typically six, each with distinct types of cells and connections. The layers are labeled from I to VI, starting from the outermost layer (closest to the surface of the brain) to the innermost layer. Each layer has a unique composition and function:<br /> * &#039;&#039;&#039;Layer I:&#039;&#039;&#039; The molecular layer, which contains few neurons and is primarily composed of [[dendrites]] and [[axons]].<br /> * &#039;&#039;&#039;Layer II:&#039;&#039;&#039; The external granular layer, which contains small [[pyramidal cells]] and [[stellate cells]].<br /> * &#039;&#039;&#039;Layer III:&#039;&#039;&#039; The external pyramidal layer, which contains medium-sized pyramidal cells.<br /> * &#039;&#039;&#039;Layer IV:&#039;&#039;&#039; The internal granular layer, which is densely packed with stellate cells and receives input from the [[thalamus]].<br /> * &#039;&#039;&#039;Layer V:&#039;&#039;&#039; The internal pyramidal layer, which contains large pyramidal cells that project to subcortical structures.<br /> * &#039;&#039;&#039;Layer VI:&#039;&#039;&#039; The multiform layer, which contains a variety of cell types and projects to the thalamus.<br /> <br /> ==Function==<br /> Cortical columns are thought to be involved in various functions, including sensory processing, motor control, and cognitive functions. Each column processes a specific type of information, such as visual, auditory, or somatosensory input. For example, in the [[primary visual cortex]], columns are organized to process information from specific regions of the visual field.<br /> <br /> ==Research and Discoveries==<br /> The concept of the cortical column was first proposed by [[Vernon Mountcastle]] in the 1950s. His research demonstrated that neurons within a column respond to similar types of stimuli, suggesting a functional organization within the cortex. Subsequent research has expanded on this idea, revealing the presence of columns in various cortical areas and their role in different types of information processing.<br /> <br /> ==Clinical Significance==<br /> Understanding the organization and function of cortical columns is important for understanding various neurological and psychiatric conditions. Abnormalities in cortical column structure and function have been implicated in disorders such as [[autism]], [[schizophrenia]], and [[epilepsy]].<br /> <br /> ==See also==<br /> * [[Cerebral cortex]]<br /> * [[Neuron]]<br /> * [[Thalamus]]<br /> * [[Primary visual cortex]]<br /> * [[Pyramidal cell]]<br /> * [[Somatosensory system]]<br /> <br /> ==References==<br /> {{Reflist}}<br /> <br /> ==External links==<br /> {{Commons category|Cerebral cortex}}<br /> <br /> [[Category:Neuroanatomy]]<br /> [[Category:Neuroscience]]<br /> [[Category:Brain]]<br /> [[Category:Medicine]]<br /> <br /> {{Neuroscience-stub}}</div>

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