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	~~'''~~Copper-64~~''' (64Cu) is a positron emitting isotope of copper, with applications in molecular imaging and therapy in nuclear medicine. It has a half-life of 12.7 hours.~~		== Copper-64 ==

	~~==Etymology==~~		[[File:Copper-ATSM-3D-spacefill.png\|thumb\|right\|3D space-filling model of Copper-ATSM]]
	~~The term "~~Copper-~~64" is derived from the element [[~~Copper]], which is a chemical element with the symbol Cu (from Latin: ''cuprum'') and atomic number 29. The "64" refers to the atomic mass number, which is the sum of protons and neutrons in the nucleus of an atom of the isotope.

	~~==Production==~~		'''Copper-64''' is a [[radioisotope]] of [[copper]] with a [[half-life]] of 12.7 hours. It is used in [[nuclear medicine]] for [[positron emission tomography]] (PET) imaging and [[radiotherapy]].
	Copper-64 is ~~produced in~~ a [[~~cyclotron~~]] ~~by bombarding a~~ [[~~Copper-63~~]] ~~target~~ with a ~~proton beam in a process called~~ [[~~proton irradiation~~]]. ~~The reaction that takes place~~ is ~~63Cu~~(~~p,n~~)~~64Cu~~.

	==~~Decay~~==		=== Properties ===
	Copper-64 decays by [[positron emission]] to [[~~Nickel-64~~]] ~~(64Ni)~~, ~~with a half-life of 12.7 hours. The positron~~ can be detected by a [[~~PET scanner~~]]~~, making 64Cu useful for medical imaging~~.		Copper-64 decays by [[beta decay]] and [[positron emission]], making it versatile for both diagnostic and therapeutic purposes. It emits [[beta particles]] and [[positrons]], which can be detected by PET scanners, providing high-resolution images of [[biological processes]] in the body.

	==~~Applications~~==		=== Production ===
	Copper-64 ~~has two main applications~~ in [[~~nuclear medicine~~]]~~: imaging~~ and ~~therapy~~.		Copper-64 is produced in [[cyclotrons]] by bombarding [[nickel-64]] with [[protons]]. The reaction involves the transformation of nickel-64 into copper-64 through a nuclear reaction. This process requires precise control of the energy and intensity of the proton beam to optimize yield and purity.

	===~~Imaging~~===		=== Applications ===
	Copper-64 ~~can be~~ used in ~~positron emission tomography (PET)~~ imaging. ~~It can be incorporated into a variety~~ of compounds, ~~allowing~~ for ~~the~~ imaging ~~of different biological processes~~.		Copper-64 is used in the development of [[radiopharmaceuticals]] for imaging and therapy. One of the most studied compounds is [[Copper-ATSM]], which is used for imaging [[hypoxia]] in [[tumors]]. Hypoxic regions in tumors are often resistant to conventional therapies, making them important targets for imaging and treatment.

	===~~Therapy~~===		==== Diagnostic Imaging ====
	~~Copper~~-64 ~~can also be~~ used in ~~targeted radiation therapy~~. It ~~emits beta particles~~, which ~~can kill cancer cells~~.		In diagnostic imaging, copper-64 is used in PET scans to visualize [[metabolic activity]] in tissues. It is particularly useful in [[oncology]] for detecting and monitoring [[cancer]] due to its ability to highlight areas of increased metabolic activity, which are often indicative of tumor growth.

	==~~Related Terms~~==		==== Therapeutic Uses ====
	* [[~~Copper~~]]		Copper-64 can also be used in [[targeted radionuclide therapy]]. Its emission of beta particles allows it to deliver therapeutic doses of radiation to specific sites, such as cancerous tissues, while minimizing damage to surrounding healthy tissues.
	* [[~~Isotope~~]]
			=== Safety and Handling ===
			As with all radioactive materials, copper-64 must be handled with care to minimize exposure to radiation. Proper [[radiation safety]] protocols must be followed, including the use of [[shielding]], [[personal protective equipment]], and [[radiation monitoring devices]].

			== Related pages ==
			* [[Radioisotope]]
	* [[Positron emission tomography]]		* [[Positron emission tomography]]
			* [[Radiopharmaceutical]]
	* [[Nuclear medicine]]		* [[Nuclear medicine]]
	* [[~~Cyclotron]]~~		* [[Copper]]
	* [[Proton irradiation]]
	* [[Beta particles]]

	[[Category:~~Medical isotopes~~]]		[[Category:Radioisotopes]]
	[[Category:Nuclear medicine]]		[[Category:Nuclear medicine]]
	~~[[Category:Radiation therapy]]~~
	~~[[Category:Medical imaging]]~~

	~~{{stub}}~~

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2024-02-19T21:45:15Z

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'''Copper-64''' (64Cu) is a positron emitting isotope of copper, with applications in molecular imaging and therapy in nuclear medicine. It has a half-life of 12.7 hours.

==Etymology==
The term "Copper-64" is derived from the element [[Copper]], which is a chemical element with the symbol Cu (from Latin: ''cuprum'') and atomic number 29. The "64" refers to the atomic mass number, which is the sum of protons and neutrons in the nucleus of an atom of the isotope.

==Production==
Copper-64 is produced in a [[cyclotron]] by bombarding a [[Copper-63]] target with a proton beam in a process called [[proton irradiation]]. The reaction that takes place is 63Cu(p,n)64Cu.

==Decay==
Copper-64 decays by [[positron emission]] to [[Nickel-64]] (64Ni), with a half-life of 12.7 hours. The positron can be detected by a [[PET scanner]], making 64Cu useful for medical imaging.

==Applications==
Copper-64 has two main applications in [[nuclear medicine]]: imaging and therapy.

===Imaging===
Copper-64 can be used in positron emission tomography (PET) imaging. It can be incorporated into a variety of compounds, allowing for the imaging of different biological processes.

===Therapy===
Copper-64 can also be used in targeted radiation therapy. It emits beta particles, which can kill cancer cells.

==Related Terms==
* [[Copper]]
* [[Isotope]]
* [[Positron emission tomography]]
* [[Nuclear medicine]]
* [[Cyclotron]]
* [[Proton irradiation]]
* [[Beta particles]]

[[Category:Medical isotopes]]
[[Category:Nuclear medicine]]
[[Category:Radiation therapy]]
[[Category:Medical imaging]]

{{stub}}

Copper-64 - Revision history

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