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	~~'''~~Coeliac UK''' is a [[charity]] organization based in the [[United Kingdom]] that provides support and resources for individuals diagnosed with [[coeliac disease]]. The organization was established in 1968 and has since been a leading authority on coeliac disease and [[dermatitis herpetiformis]], a skin condition associated with coeliac disease.		== Coeliac Disease ==

	~~== History ==~~		[[File:Coeliac-logo.png\|thumb\|right\|Logo of Coeliac UK]]

	Coeliac ~~UK was founded in 1968 by several individuals who were affected by coeliac~~ disease~~. The organization was initially known as the Coeliac Society before it was renamed to Coeliac UK. The organization~~'~~s primary goal~~ is ~~to improve~~ the ~~lives~~ of ~~people diagnosed with coeliac disease through research~~, ~~advocacy~~, and ~~education~~.		'''Coeliac disease''' is an [[autoimmune disorder]] that primarily affects the [[small intestine]]. It occurs in genetically predisposed people of all ages from middle infancy onward. Symptoms include chronic [[diarrhea]], abdominal distention, malabsorption, loss of appetite, and among children, failure to grow normally.

	== ~~Activities~~ ==		== Pathophysiology ==

	Coeliac ~~UK provides~~ a ~~wide range of services~~ to ~~support individuals with coeliac disease. These include providing information~~ and ~~advice on managing~~ the ~~disease~~, ~~promoting research into coeliac disease~~, and ~~advocating for~~ the ~~rights~~ of ~~people~~ with ~~coeliac disease~~.		Coeliac disease is caused by a reaction to [[gliadin]], a prolamin (gluten protein) found in wheat, and similar proteins found in the crops of the [[Triticeae]] tribe, which includes other common grains such as [[barley]] and [[rye]]. Upon exposure to gliadin, the enzyme [[tissue transglutaminase]] modifies the protein, and the immune system cross-reacts with the small-bowel tissue, causing an inflammatory reaction. This leads to a truncating of the [[villi]] lining the small intestine (villous atrophy), which interferes with the absorption of nutrients.

	The organization also provides resources for healthcare professionals to improve their understanding and management of coeliac disease. This includes training materials, guidelines for diagnosis and management, and information on the latest research.		== Diagnosis ==

	~~== Research ==~~		The diagnosis of coeliac disease is typically confirmed by [[serology]] and [[biopsy]]. Serological tests look for specific antibodies, such as anti-tissue transglutaminase (tTG) and anti-endomysial antibodies (EMA). A definitive diagnosis is made through a biopsy of the small intestine, which shows villous atrophy and crypt hyperplasia.

	Coeliac UK is involved in various research initiatives aimed at improving the understanding and treatment of coeliac disease. The organization funds research projects, collaborates with other research institutions, and promotes the participation of people with coeliac disease in research studies.		== Treatment ==

	~~== Advocacy ==~~		The only effective treatment for coeliac disease is a lifelong [[gluten-free diet]]. This involves the avoidance of foods containing wheat, barley, rye, and derivatives of these grains. Adherence to a gluten-free diet allows the intestinal mucosa to heal, alleviates symptoms, and reduces the risk of complications.

	Coeliac UK advocates for the rights of people with coeliac disease. This includes lobbying for better access to gluten-free food, advocating for improved diagnosis rates, and campaigning for better understanding and management of the disease.		== Complications ==

	~~== See also ==~~		If untreated, coeliac disease can lead to several complications, including [[osteoporosis]], [[infertility]], neurological conditions, and an increased risk of certain types of [[cancer]], such as intestinal lymphoma.

	* [[Coeliac disease]]		== Epidemiology ==
	* [[Dermatitis herpetiformis]]
	* [[Gluten-free diet]]

	~~== References ==~~		Coeliac disease affects approximately 1% of the population worldwide, although many cases remain undiagnosed. It is more common in individuals of European descent and is less common in people of Asian and African descent.

	~~<references />~~		== Related pages ==

	[[~~Category:Charities based in the United Kingdom~~]]		* [[Gluten-free diet]]
	[[~~Category:Health charities in the United Kingdom~~]]		* [[Autoimmune disease]]
	[[~~Category:Coeliac disease~~]]		* [[Malabsorption]]
	[[~~Category:Organizations established in 1968~~]]		* [[Small intestine]]

	~~{{UK-charity-stub}}~~		[[Category:Autoimmune diseases]]
	~~{{medicine-stub}}~~		[[Category:Gastroenterology]]

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'''Coeliac UK''' is a [[charity]] organization based in the [[United Kingdom]] that provides support and resources for individuals diagnosed with [[coeliac disease]]. The organization was established in 1968 and has since been a leading authority on coeliac disease and [[dermatitis herpetiformis]], a skin condition associated with coeliac disease.

== History ==

Coeliac UK was founded in 1968 by several individuals who were affected by coeliac disease. The organization was initially known as the Coeliac Society before it was renamed to Coeliac UK. The organization's primary goal is to improve the lives of people diagnosed with coeliac disease through research, advocacy, and education.

== Activities ==

Coeliac UK provides a wide range of services to support individuals with coeliac disease. These include providing information and advice on managing the disease, promoting research into coeliac disease, and advocating for the rights of people with coeliac disease.

The organization also provides resources for healthcare professionals to improve their understanding and management of coeliac disease. This includes training materials, guidelines for diagnosis and management, and information on the latest research.

== Research ==

Coeliac UK is involved in various research initiatives aimed at improving the understanding and treatment of coeliac disease. The organization funds research projects, collaborates with other research institutions, and promotes the participation of people with coeliac disease in research studies.

== Advocacy ==

Coeliac UK advocates for the rights of people with coeliac disease. This includes lobbying for better access to gluten-free food, advocating for improved diagnosis rates, and campaigning for better understanding and management of the disease.

== See also ==

* [[Coeliac disease]]
* [[Dermatitis herpetiformis]]
* [[Gluten-free diet]]

== References ==

<references />

[[Category:Charities based in the United Kingdom]]
[[Category:Health charities in the United Kingdom]]
[[Category:Coeliac disease]]
[[Category:Organizations established in 1968]]

{{UK-charity-stub}}
{{medicine-stub}}

Coeliac UK - Revision history

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