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	'''Clay Armstrong''' (1934~~-2018~~) ~~was~~ an ~~eminent [[neuroscientist]]~~ and [[biophysicist~~]], best known~~ for his ~~groundbreaking work in the field of~~ [[ion ~~channel~~]] ~~physiology~~. His ~~research~~ has significantly ~~contributed to our~~ understanding of how ~~cells communicate and has had profound implications for the treatment of~~ [[~~neurological disorders~~]].
			{{Infobox scientist
			\| name = Clay Armstrong
			\| image =
			\| image_size =
			\| alt =
			\| caption =
			\| birth_date = January 18, 1934
			\| birth_place = New Orleans, Louisiana, USA
			\| nationality = American
			\| fields = Physiology, Biophysics
			\| work_institutions = University of Pennsylvania
			\| alma_mater = Washington and Lee University, Duke University
			\| known_for = [[Ion channel]] research
			\| awards = [[Albert Lasker Award for Basic Medical Research]], [[Louisa Gross Horwitz Prize]], [[Gairdner Foundation International Award]]
			}}

			'''Clay Armstrong''' (born January 18, 1934) is an American physiologist and biophysicist renowned for his pioneering research on [[ion channels]]. His work has significantly advanced the understanding of how ions move across cell membranes, a fundamental process in [[neurophysiology]].

	== Early Life and Education ==		== Early Life and Education ==
	Armstrong was born ~~in 1934~~ in [[~~Los Angeles~~]], [[~~California~~]]. He completed his undergraduate studies at [[~~Pomona College~~]] ~~in 1956, majoring in [[physics]]. He then pursued~~ his ~~Ph.D. in~~ [[~~biophysics]] at [[Johns Hopkins~~ University]]~~, which he completed in 1963~~.		Clay Armstrong was born in [[New Orleans]], [[Louisiana]]. He completed his undergraduate studies at [[Washington and Lee University]] and went on to earn his medical degree from [[Duke University]].

	== Career ==		== Career ==
	~~After completing his Ph.D.,~~ Armstrong ~~joined the faculty at~~ the [[University of Pennsylvania]] ~~as an assistant professor~~ in ~~the Department of~~ [[~~Physiology~~]]~~. He was promoted to full professor in 1973. During his tenure at the university, he made several significant discoveries related to the function and structure of ion channels~~.		Armstrong's career has been primarily associated with the [[University of Pennsylvania]], where he has conducted much of his groundbreaking research. His studies have focused on the mechanisms by which ion channels operate, particularly in [[nerve cells]].

	Armstrong~~'s most notable contribution to science was~~ his ~~"gating current" theory. He proposed that~~ ion ~~channels open~~ and ~~close~~ in ~~response to changes~~ in ~~the electrical charge across the cell membrane, a process known as~~ [[~~voltage gating~~]]~~. This theory revolutionized our understanding of how nerve cells transmit signals~~ and has ~~had far-reaching implications for the treatment of neurological disorders~~.		== Research Contributions ==
			Armstrong is best known for his work on the [[voltage-gated ion channel]]s, which are crucial for the generation and propagation of [[action potentials]] in neurons. His research has elucidated the role of these channels in [[electrical signaling]] and has provided insights into their structure and function.

	== ~~Legacy~~ ==		=== Ion Channel Research ===
	Armstrong's ~~work has had~~ a ~~profound impact on~~ the ~~field of neuroscience~~. His ~~research~~ has ~~not only advanced our~~ understanding ~~of how cells communicate, but it has also paved the way for the development of new treatments for~~ neurological disorders~~. Armstrong passed away in 2018, but his legacy continues to influence the field of neuroscience~~.		Armstrong's investigations into ion channels have revealed how these proteins selectively allow ions to pass through the [[cell membrane]], a process essential for maintaining the [[electrochemical gradient]] across the membrane. His work has implications for understanding various [[neurological disorders]] and developing potential treatments.

	[[~~File:Clay_Armstrong~~.~~jpg\|thumb\|right\|Clay Armstrong~~]]		== Awards and Honors ==
			Clay Armstrong has received numerous prestigious awards in recognition of his contributions to science, including the [[Albert Lasker Award for Basic Medical Research]], the [[Louisa Gross Horwitz Prize]], and the [[Gairdner Foundation International Award]]. These accolades highlight his impact on the field of [[biophysics]] and [[physiology]].

	== See Also ==		== See Also ==
	* [[Ion channel]]		* [[Ion channel]]
	* [[~~Neuroscience~~]]		* [[Neurophysiology]]
	* [[~~Biophysics]]~~		* [[Action potential]]
	* [[Voltage gating]]

	== References ==		== References ==
	~~<references~~ />		* [https://www.wikimd.com/wiki/Clay_Armstrong Clay Armstrong - WikiMD]

			== External Links ==
			* [https://www.pennmedicine.org/ University of Pennsylvania]

	[[Category:~~Neuroscientists~~]]		{{DEFAULTSORT:Armstrong, Clay}}
	[[Category:~~Biophysicists~~]]		[[Category:1934 births]]
			[[Category:Living people]]
			[[Category:American physiologists]]
			[[Category:American biophysicists]]
	[[Category:University of Pennsylvania faculty]]		[[Category:University of Pennsylvania faculty]]
	[[Category:~~Johns Hopkins~~ University alumni]]		[[Category:Washington and Lee University alumni]]
	[[Category:~~Pomona College~~ alumni]]		[[Category:Duke University alumni]]
			[[Category:Ion channels]]
	~~{{medicine-stub}}~~

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'''Clay Armstrong''' (1934-2018) was an eminent [[neuroscientist]] and [[biophysicist]], best known for his groundbreaking work in the field of [[ion channel]] physiology. His research has significantly contributed to our understanding of how cells communicate and has had profound implications for the treatment of [[neurological disorders]].

== Early Life and Education ==
Armstrong was born in 1934 in [[Los Angeles]], [[California]]. He completed his undergraduate studies at [[Pomona College]] in 1956, majoring in [[physics]]. He then pursued his Ph.D. in [[biophysics]] at [[Johns Hopkins University]], which he completed in 1963.

== Career ==
After completing his Ph.D., Armstrong joined the faculty at the [[University of Pennsylvania]] as an assistant professor in the Department of [[Physiology]]. He was promoted to full professor in 1973. During his tenure at the university, he made several significant discoveries related to the function and structure of ion channels.

Armstrong's most notable contribution to science was his "gating current" theory. He proposed that ion channels open and close in response to changes in the electrical charge across the cell membrane, a process known as [[voltage gating]]. This theory revolutionized our understanding of how nerve cells transmit signals and has had far-reaching implications for the treatment of neurological disorders.

== Legacy ==
Armstrong's work has had a profound impact on the field of neuroscience. His research has not only advanced our understanding of how cells communicate, but it has also paved the way for the development of new treatments for neurological disorders. Armstrong passed away in 2018, but his legacy continues to influence the field of neuroscience.

[[File:Clay_Armstrong.jpg|thumb|right|Clay Armstrong]]

== See Also ==
* [[Ion channel]]
* [[Neuroscience]]
* [[Biophysics]]
* [[Voltage gating]]

== References ==
<references />

[[Category:Neuroscientists]]
[[Category:Biophysicists]]
[[Category:University of Pennsylvania faculty]]
[[Category:Johns Hopkins University alumni]]
[[Category:Pomona College alumni]]

{{medicine-stub}}

Clay Armstrong - Revision history

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