https://wikimd.org/index.php?action=history&feed=atom&title=Chromosome_12Chromosome 12 - Revision history2026-04-27T08:02:44ZRevision history for this page on the wikiMediaWiki 1.44.2https://wikimd.org/index.php?title=Chromosome_12&diff=6319705&oldid=prevPrab: CSV import2025-02-18T04:58:49Z<p>CSV import</p>
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<p><b>New page</b></p><div>'''Chromosome 12''' is one of the 23 pairs of [[chromosomes]] in humans. People normally have two copies of this chromosome. Chromosome 12 spans about 133 million [[base pairs]] (the building material of [[DNA]]) and represents between 4 and 4.5 percent of the total DNA in [[cells]].<br />
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==Genes==<br />
Chromosome 12 contains about 1,100 to 1,400 [[genes]]. Some of the genes that are located on Chromosome 12 include [[KRAS]], which provides instructions for making a protein that is involved in regulating cell division, and [[POU1F1]], which is involved in the development of the pituitary gland and its production of certain hormones.<br />
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==Diseases and disorders==<br />
Certain genetic conditions are related to mutations in genes on Chromosome 12. For example, [[Noonan syndrome]] is associated with mutations in the KRAS gene. Other conditions, such as [[hypopituitarism]], can result from mutations in the POU1F1 gene.<br />
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==Research==<br />
Research is ongoing to identify additional genes on Chromosome 12 and to learn more about the role these genes play in health and disease. This research will lead to a better understanding of the genetic basis of many conditions and may eventually lead to new treatments.<br />
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==See also==<br />
* [[Human genome]]<br />
* [[Genetic disorder]]<br />
* [[Gene therapy]]<br />
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==References==<br />
* National Library of Medicine. Genetics Home Reference. Chromosome 12.<br />
* National Human Genome Research Institute. Chromosome 12.<br />
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[[Category:Chromosomes]]<br />
[[Category:Genetics]]<br />
{{genetics-stub}}</div>Prab