https://wikimd.com/index.php?action=history&feed=atom&title=Chromosome_10p_duplication 2026-04-15T23:27:41Z Revision history for this page on the wiki MediaWiki 1.44.2 https://wikimd.com/index.php?title=Chromosome_10p_duplication&diff=2099420&oldid=prev 2020-09-09T11:39:07Z

<p>Created page with &quot;&#039;&#039;&#039;Other Names:&#039;&#039;&#039; Duplication 10p; Trisomy 10p; 10p duplication; 10p trisomy; Partial trisomy 10p Chromosome 10p duplication is a <a href="/wiki/Chromosome" title="Chromosome">chromosome</a> abnormality that occurs when...&quot;</p> <p><b>New page</b></p><div>&#039;&#039;&#039;Other Names:&#039;&#039;&#039; Duplication 10p; Trisomy 10p; 10p duplication; 10p trisomy; Partial trisomy 10p<br /> <br /> Chromosome 10p duplication is a [[chromosome]] abnormality that occurs when there is an &#039;&#039;&#039;extra copy&#039;&#039;&#039; of genetic material on the short arm (p) of [[chromosome 10]].<br /> The severity and the signs and symptoms depend on the size and location of the duplication and which genes are involved. The size of the duplication can range from a tiny piece of the chromosome arm, to the entire arm.<br /> <br /> == &#039;&#039;&#039;Cause and inheritance&#039;&#039;&#039; ==<br /> Some 10p duplications are not inherited and occur [[sporadically]] (randomly) when [[egg]] or [[sperm]] cells form, or shortly after the egg and sperm join together. In other cases, the duplication occurs because a parent has a [[chromosome]] rearrangement such as a balanced translocation or a [[pericentric inversion]] (neither of which usually causes health problems). A chromosome test of both parents can help determine whether the duplication was inherited, and whether future children have an increased chance to have a chromosome abnormality.<br /> <br /> == &#039;&#039;&#039;Signs and symptoms&#039;&#039;&#039; ==<br /> Signs and symptoms that can be present in a person with a 10p duplication may include delay of development, [[motor skills]], or growth; short stature; low muscle tone ([[hypotonia]]); abnormalities of the foot (such as clubfoot); cleft lip and/or [[cleft palate]]; and distinctive facial features. Other signs and symptoms may include [[seizures]], a heart defect, or other birth defects.<br /> <br /> Treatment<br /> Treatment is based on the signs and symptoms present in each person.<br /> <br /> {{rarediseases}}<br /> {{stub}}</div>

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