https://wikimd.com/index.php?action=history&feed=atom&title=Capivasertib 2026-04-22T23:17:18Z Revision history for this page on the wiki MediaWiki 1.44.2 https://wikimd.com/index.php?title=Capivasertib&diff=5805435&oldid=prev 2024-05-20T06:47:48Z

<p>CSV import</p> <p><b>New page</b></p><div>[[File:Capivasertib.svg|thumb|right]] &#039;&#039;&#039;Capivasertib&#039;&#039;&#039; is an investigational drug that functions as a selective inhibitor of the [[AKT]] (protein kinase B) pathway. It is being studied for its potential use in the treatment of various types of [[cancer]].<br /> <br /> ==Mechanism of Action==<br /> Capivasertib targets and inhibits the activity of the [[AKT]] enzyme, which plays a crucial role in the [[PI3K/AKT/mTOR pathway]]. This pathway is involved in cell growth, proliferation, and survival. By inhibiting [[AKT]], Capivasertib can potentially reduce tumor growth and induce [[apoptosis]] in cancer cells.<br /> <br /> ==Clinical Development==<br /> Capivasertib is currently undergoing clinical trials to evaluate its efficacy and safety in treating different types of cancer, including [[breast cancer]], [[prostate cancer]], and [[lung cancer]]. These trials are designed to determine the optimal dosing, potential side effects, and overall effectiveness of the drug.<br /> <br /> ==Potential Indications==<br /> Capivasertib is being investigated for use in several types of cancer, particularly those that exhibit aberrant activation of the [[PI3K/AKT/mTOR pathway]]. Some of the cancers under investigation include:<br /> * [[Breast cancer]]<br /> * [[Prostate cancer]]<br /> * [[Lung cancer]]<br /> * [[Ovarian cancer]]<br /> <br /> ==Side Effects==<br /> As with many investigational drugs, Capivasertib may cause a range of side effects. Commonly reported side effects in clinical trials include:<br /> * [[Nausea]]<br /> * [[Diarrhea]]<br /> * [[Fatigue]]<br /> * [[Rash]]<br /> * [[Hyperglycemia]]<br /> <br /> ==Research and Future Directions==<br /> Ongoing research aims to better understand the full potential of Capivasertib in cancer therapy. This includes exploring its use in combination with other treatments, such as [[chemotherapy]], [[radiation therapy]], and other targeted therapies. Researchers are also investigating biomarkers that may predict which patients are most likely to benefit from Capivasertib treatment.<br /> <br /> ==See Also==<br /> * [[AKT]]<br /> * [[PI3K/AKT/mTOR pathway]]<br /> * [[Targeted therapy]]<br /> * [[Cancer treatment]]<br /> <br /> ==References==<br /> {{Reflist}}<br /> <br /> ==External Links==<br /> {{Commons category|Capivasertib}}<br /> <br /> [[Category:Antineoplastic drugs]]<br /> [[Category:Experimental cancer drugs]]<br /> [[Category:Protein kinase inhibitors]]<br /> [[Category:Medicine]]<br /> <br /> {{medicine-stub}}</div>

Prab