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<p>CSV import</p> <p><b>New page</b></p><div>[[file:Hepatic_structure2.svg|thumb|left]] &#039;&#039;&#039;Canals of Hering&#039;&#039;&#039;<br /> <br /> The &#039;&#039;&#039;Canals of Hering&#039;&#039;&#039;, also known as &#039;&#039;&#039;Hering&#039;s canals&#039;&#039;&#039;, are small ductules in the liver that play a crucial role in the [[biliary system]]. These canals are part of the [[intrahepatic bile duct]] system and are essential for the transport of bile from the [[hepatocytes]] to the larger bile ducts.<br /> <br /> ==Structure==<br /> The Canals of Hering are located at the interface between the [[hepatocytes]] and the [[bile ductules]]. They are lined by both [[hepatocytes]] and [[cholangiocytes]], which are the epithelial cells of the bile ducts. This unique lining allows for the transition of bile from the liver cells to the bile ducts.<br /> <br /> ==Function==<br /> The primary function of the Canals of Hering is to collect bile produced by the [[hepatocytes]] and transport it to the [[bile ductules]]. From the bile ductules, bile is then transported to the larger [[intrahepatic bile ducts]], and eventually to the [[common bile duct]], which carries bile to the [[gallbladder]] and the [[duodenum]] for digestion.<br /> <br /> ==Clinical Significance==<br /> Damage or obstruction of the Canals of Hering can lead to various liver diseases, including [[cholestasis]], where bile flow is impaired. This can result in the accumulation of bile acids in the liver, causing liver damage and jaundice. The Canals of Hering are also a site of origin for certain types of liver cancer, such as [[cholangiocarcinoma]].<br /> <br /> ==Regeneration==<br /> The Canals of Hering are believed to play a role in liver regeneration. They contain a population of progenitor cells, also known as [[oval cells]], which can differentiate into both [[hepatocytes]] and [[cholangiocytes]]. This regenerative capacity is particularly important in conditions where the liver is damaged and needs to repair itself.<br /> <br /> ==History==<br /> The Canals of Hering are named after [[Ewald Hering]], a German physiologist who first described these structures. His work laid the foundation for understanding the complex anatomy and function of the liver&#039;s biliary system.<br /> <br /> ==See Also==<br /> * [[Biliary system]]<br /> * [[Hepatocyte]]<br /> * [[Cholangiocyte]]<br /> * [[Intrahepatic bile duct]]<br /> * [[Cholestasis]]<br /> * [[Cholangiocarcinoma]]<br /> <br /> ==References==<br /> {{Reflist}}<br /> <br /> ==External Links==<br /> {{Commons category|Canals of Hering}}<br /> <br /> [[Category:Liver anatomy]]<br /> [[Category:Hepatology]]<br /> [[Category:Digestive system]]<br /> [[Category:Histology]]<br /> <br /> {{medicine-stub}}</div>

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