Calcifying odontogenic cyst - Revision history

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			{{SI}}
			{{Infobox medical condition
			\| name = Calcifying odontogenic cyst
			\| image = [[File:Human_jawbone_left.jpg\|250px]]
			\| caption = Radiograph showing a calcifying odontogenic cyst in the jaw
			\| field = [[Oral and maxillofacial pathology]]
			\| synonyms = Gorlin cyst
			\| symptoms = Swelling, pain, tooth displacement
			\| complications = [[Tooth resorption]], [[jaw fracture]]
			\| onset = Typically in the second to third decade of life
			\| duration = Variable
			\| types = Cystic, solid
			\| causes = Unknown
			\| risks = None specifically identified
			\| diagnosis = [[Radiograph]], [[biopsy]]
			\| differential = [[Ameloblastoma]], [[odontoma]], [[dentigerous cyst]]
			\| treatment = Surgical excision
			\| medication = None
			\| prognosis = Generally good with treatment
			\| frequency = Rare
			}}
	{{Short description\|A type of odontogenic cyst}}		{{Short description\|A type of odontogenic cyst}}
	~~{{Use dmy dates\|date=October 2023}}~~

	The '''calcifying odontogenic cyst''' (COC), also known as the '''Gorlin cyst''', is a rare type of [[odontogenic cyst]] that can occur in the [[jawbone]] or [[gingiva]]. It is characterized by the presence of [[ghost cells]] and calcifications within the cystic structure. This cyst is considered to be a developmental anomaly and can present in a variety of clinical forms.		The '''calcifying odontogenic cyst''' (COC), also known as the '''Gorlin cyst''', is a rare type of [[odontogenic cyst]] that can occur in the [[jawbone]] or [[gingiva]]. It is characterized by the presence of [[ghost cells]] and calcifications within the cystic structure. This cyst is considered to be a developmental anomaly and can present in a variety of clinical forms.

	==Clinical Presentation==		==Clinical Presentation==
	The calcifying odontogenic cyst can occur at any age, but it is most commonly diagnosed in the second to third decades of life. It has no gender predilection and can occur in both the [[maxilla]] and [[mandible]], although it is more frequently found in the anterior regions of the jaws.		The calcifying odontogenic cyst can occur at any age, but it is most commonly diagnosed in the second to third decades of life. It has no gender predilection and can occur in both the [[maxilla]] and [[mandible]], although it is more frequently found in the anterior regions of the jaws.

	Patients with a calcifying odontogenic cyst may present with a painless swelling in the jaw, although some cases may be associated with pain or discomfort. The cyst can cause expansion of the cortical bone and may be associated with an impacted tooth.		Patients with a calcifying odontogenic cyst may present with a painless swelling in the jaw, although some cases may be associated with pain or discomfort. The cyst can cause expansion of the cortical bone and may be associated with an impacted tooth.

	==Pathology==		==Pathology==
	The calcifying odontogenic cyst is histologically characterized by a cystic lining that contains ghost cells, which are enlarged epithelial cells that have lost their nuclei and have a pale eosinophilic cytoplasm. These ghost cells can undergo calcification, leading to the formation of calcified masses within the cyst.		The calcifying odontogenic cyst is histologically characterized by a cystic lining that contains ghost cells, which are enlarged epithelial cells that have lost their nuclei and have a pale eosinophilic cytoplasm. These ghost cells can undergo calcification, leading to the formation of calcified masses within the cyst.
			[[File:Relative_incidence_of_odontogenic_cysts.jpg\|Relative incidence of odontogenic cysts\|left\|thumb]]
	[[File:Relative_incidence_of_odontogenic_cysts.jpg\|Relative incidence of odontogenic cysts\|thumb~~\|right~~]]

	The cyst may also contain areas of odontogenic epithelium and may be associated with other odontogenic tumors, such as the [[odontoma]].		The cyst may also contain areas of odontogenic epithelium and may be associated with other odontogenic tumors, such as the [[odontoma]].

	==Radiographic Features==		==Radiographic Features==
	Radiographically, the calcifying odontogenic cyst appears as a well-defined radiolucency that may contain radiopaque foci due to calcifications. It can be unilocular or multilocular and may cause displacement of adjacent teeth.		Radiographically, the calcifying odontogenic cyst appears as a well-defined radiolucency that may contain radiopaque foci due to calcifications. It can be unilocular or multilocular and may cause displacement of adjacent teeth.

	==Treatment==		==Treatment==
	The treatment of choice for a calcifying odontogenic cyst is surgical enucleation. The prognosis is generally good, with a low recurrence rate after complete removal. In some cases, more aggressive surgical approaches may be necessary if the cyst is associated with other odontogenic tumors.		The treatment of choice for a calcifying odontogenic cyst is surgical enucleation. The prognosis is generally good, with a low recurrence rate after complete removal. In some cases, more aggressive surgical approaches may be necessary if the cyst is associated with other odontogenic tumors.
			==See also==
	==~~Related Pages~~==
	* [[Odontogenic cyst]]		* [[Odontogenic cyst]]
	* [[Odontogenic tumor]]		* [[Odontogenic tumor]]
	* [[Ghost cell]]		* [[Ghost cell]]
			[[File:Human_jawbone_left.jpg\|Calcifying odontogenic cyst\|left\|thumb]]
	[[File:Human_jawbone_left.jpg\|Calcifying odontogenic cyst\|thumb~~\|left~~]]

	==See Also==		==See Also==
	* [[Gorlin syndrome]]		* [[Gorlin syndrome]]
	* [[Ameloblastoma]]		* [[Ameloblastoma]]

	{{Odontogenic tumors}}		{{Odontogenic tumors}}

	[[Category:Odontogenic cysts]]		[[Category:Odontogenic cysts]]
	[[Category:Oral pathology]]		[[Category:Oral pathology]]

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	~~'''Calcifying odontogenic cyst''' ('''COC''') is a rare and unique~~ type of ~~[[odontogenic cyst]] that is characterized by its histopathological features, which include a cystic lining or solid mass that resembles the [[~~odontogenic ~~epithelium]]. It was first described by Gorlin et al. in 1962, hence it is also known as '''Gorlin~~ cyst~~'''.~~		{{Short description\|A type of odontogenic cyst}}
			{{Use dmy dates\|date=October 2023}}

	~~==Epidemiology==~~		The '''calcifying odontogenic cyst''' (COC), also known as the '''Gorlin cyst''', is a rare type of [[odontogenic cyst]] that can occur in the [[jawbone]] or [[gingiva]]. It is characterized by the presence of [[ghost cells]] and calcifications within the cystic structure. This cyst is considered to be a developmental anomaly and can present in a variety of clinical forms.
	COC ~~accounts for approximately 1%~~ of ~~all~~ odontogenic ~~cysts~~. It ~~can occur at any age, but it~~ is ~~most commonly diagnosed in~~ the ~~second~~ and ~~third decades of life~~. ~~There~~ is ~~no significant gender predilection~~.

	==Clinical ~~Features~~==		==Clinical Presentation==
	~~Clinically~~, ~~COC may present as a painless swelling~~ in the ~~jaw~~. It can occur in ~~either~~ the [[maxilla]] ~~or the~~ [[mandible]], ~~but~~ it is more ~~commonly~~ found in the anterior ~~region~~ of the jaws~~. Radiographically, it appears as a well-defined radiolucent lesion with varying degrees of calcification~~.		The calcifying odontogenic cyst can occur at any age, but it is most commonly diagnosed in the second to third decades of life. It has no gender predilection and can occur in both the [[maxilla]] and [[mandible]], although it is more frequently found in the anterior regions of the jaws.

	~~==Histopathology==~~		Patients with a calcifying odontogenic cyst may present with a painless swelling in the jaw, although some cases may be associated with pain or discomfort. The cyst can cause expansion of the cortical bone and may be associated with an impacted tooth.
	~~The histopathological features of COC are distinctive. The cystic lining or solid mass is characterized by an ameloblastoma-like epithelium~~ with ~~stellate reticulum-like areas. Ghost cells~~, ~~which are enlarged epithelial cells~~ with ~~eosinophilic cytoplasm~~ and ~~no nucleus, are a characteristic feature of COC. Calcification is often seen~~ associated with ~~these ghost cells~~.

	==Treatment ~~and Prognosis~~==		==Pathology==
	The treatment of choice for ~~COC~~ is surgical enucleation. The prognosis is generally good, with a low recurrence rate. ~~However, malignant transformation has been reported in~~ some cases.		The calcifying odontogenic cyst is histologically characterized by a cystic lining that contains ghost cells, which are enlarged epithelial cells that have lost their nuclei and have a pale eosinophilic cytoplasm. These ghost cells can undergo calcification, leading to the formation of calcified masses within the cyst.

			[[File:Relative_incidence_of_odontogenic_cysts.jpg\|Relative incidence of odontogenic cysts\|thumb\|right]]

			The cyst may also contain areas of odontogenic epithelium and may be associated with other odontogenic tumors, such as the [[odontoma]].

			==Radiographic Features==
			Radiographically, the calcifying odontogenic cyst appears as a well-defined radiolucency that may contain radiopaque foci due to calcifications. It can be unilocular or multilocular and may cause displacement of adjacent teeth.

			==Treatment==
			The treatment of choice for a calcifying odontogenic cyst is surgical enucleation. The prognosis is generally good, with a low recurrence rate after complete removal. In some cases, more aggressive surgical approaches may be necessary if the cyst is associated with other odontogenic tumors.

			==Related Pages==
			* [[Odontogenic cyst]]
			* [[Odontogenic tumor]]
			* [[Ghost cell]]

			[[File:Human_jawbone_left.jpg\|Calcifying odontogenic cyst\|thumb\|left]]

	==See Also==		==See Also==
	* [[~~Odontogenic cyst]]~~		* [[Gorlin syndrome]]
	* [[Odontogenic tumors]]
	* [[Ameloblastoma]]		* [[Ameloblastoma]]
	* [[Ghost cell]]

	~~==References==~~		{{Odontogenic tumors}}
	~~<references />~~

			[[Category:Odontogenic cysts]]
	[[Category:Oral pathology]]		[[Category:Oral pathology]]
	~~[[Category:Odontogenic cysts]]~~
	~~[[Category:Rare diseases]]~~
	~~{{Oral pathology}}~~
	~~{{Rare diseases}}~~
	~~{{Odontogenic cysts}}~~
	~~{{medicine-stub}}~~
	~~<gallery>~~
	~~File:Relative_incidence_of_odontogenic_cysts.jpg\|Relative incidence of odontogenic cysts~~
	~~</gallery>~~
	~~<gallery>~~
	~~File:Human_jawbone_left.jpg\|Calcifying odontogenic cyst~~
	~~File:Relative_incidence_of_odontogenic_cysts.jpg\|Relative incidence of odontogenic cysts~~
	~~</gallery>~~

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2025-02-18T01:47:17Z

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	{{medicine-stub}}		{{medicine-stub}}
	<gallery>		<gallery>
			File:Relative_incidence_of_odontogenic_cysts.jpg\|Relative incidence of odontogenic cysts
			</gallery>
			<gallery>
			File:Human_jawbone_left.jpg\|Calcifying odontogenic cyst
	File:Relative_incidence_of_odontogenic_cysts.jpg\|Relative incidence of odontogenic cysts		File:Relative_incidence_of_odontogenic_cysts.jpg\|Relative incidence of odontogenic cysts
	</gallery>		</gallery>

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	{{Odontogenic cysts}}		{{Odontogenic cysts}}
	{{medicine-stub}}		{{medicine-stub}}
			<gallery>
			File:Relative_incidence_of_odontogenic_cysts.jpg\|Relative incidence of odontogenic cysts
			</gallery>

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New page

'''Calcifying odontogenic cyst''' ('''COC''') is a rare and unique type of [[odontogenic cyst]] that is characterized by its histopathological features, which include a cystic lining or solid mass that resembles the [[odontogenic epithelium]]. It was first described by Gorlin et al. in 1962, hence it is also known as '''Gorlin cyst'''.

==Epidemiology==
COC accounts for approximately 1% of all odontogenic cysts. It can occur at any age, but it is most commonly diagnosed in the second and third decades of life. There is no significant gender predilection.

==Clinical Features==
Clinically, COC may present as a painless swelling in the jaw. It can occur in either the [[maxilla]] or the [[mandible]], but it is more commonly found in the anterior region of the jaws. Radiographically, it appears as a well-defined radiolucent lesion with varying degrees of calcification.

==Histopathology==
The histopathological features of COC are distinctive. The cystic lining or solid mass is characterized by an ameloblastoma-like epithelium with stellate reticulum-like areas. Ghost cells, which are enlarged epithelial cells with eosinophilic cytoplasm and no nucleus, are a characteristic feature of COC. Calcification is often seen associated with these ghost cells.

==Treatment and Prognosis==
The treatment of choice for COC is surgical enucleation. The prognosis is generally good, with a low recurrence rate. However, malignant transformation has been reported in some cases.

==See Also==
* [[Odontogenic cyst]]
* [[Odontogenic tumors]]
* [[Ameloblastoma]]
* [[Ghost cell]]

==References==
<references />

[[Category:Oral pathology]]
[[Category:Odontogenic cysts]]
[[Category:Rare diseases]]
{{Oral pathology}}
{{Rare diseases}}
{{Odontogenic cysts}}
{{medicine-stub}}