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	~~'''~~CUMYL-PICA''' is a compound that belongs to the class of [[drug]]s known as [[synthetic cannabinoids]]. It is a potent [[agonist]] of the [[CB1 receptor]] and [[CB2 receptor]], which are part of the [[endocannabinoid system]] in the human body. CUMYL-PICA is often used in scientific research, but it has also been found in synthetic cannabis products sold for recreational use.		== CUMYL-PICA ==

	~~==Chemistry==~~		[[File:CUMYL-PICA_structure.png\|thumb\|right\|Chemical structure of CUMYL-PICA]]

	CUMYL-PICA is a ~~derivative~~ of ~~[[indole]] and is structurally related~~ to ~~other synthetic cannabinoids such as~~ [[~~5F-PB-22~~]] ~~and~~ [[~~BB-22~~]]. It has a cumyl group, which is a functional group consisting of a phenyl group attached to a tert-butyl group, attached to the indole ring through an amide linkage. The specific name CUMYL-PICA refers to the particular structure of this compound, where PICA stands for "PIndoleCArboxamide".		'''CUMYL-PICA''' is a synthetic cannabinoid that has been identified in various designer drug products. It is part of a class of compounds that are designed to mimic the effects of [[tetrahydrocannabinol]] (THC), the active component of [[cannabis]]. These substances are often used recreationally and can have potent psychoactive effects.

	==~~Pharmacology~~==		=== Chemical Structure ===
			CUMYL-PICA is chemically classified as an indole-based synthetic cannabinoid. Its full chemical name is ''1-(4-cyanobutyl)-N-(2-phenylpropan-2-yl)-1H-indole-3-carboxamide''. The structure of CUMYL-PICA includes an indole core, which is a common feature among many synthetic cannabinoids. The presence of a cyanobutyl group and a phenylpropan-2-yl group distinguishes it from other compounds in this class.

	~~As an agonist of~~ the CB1 and CB2 receptors~~, CUMYL-PICA can produce effects similar to those~~ of [[~~cannabis (drug)\|cannabis~~]]~~. However~~, ~~due to its synthetic nature and the potential for variations~~ in ~~its chemical structure~~, ~~the effects of CUMYL-PICA can be unpredictable~~ and ~~potentially harmful~~. The ~~exact mechanisms of action~~ of CUMYL-PICA ~~are not fully understood, but it is thought~~ to ~~work by mimicking the~~ effects of ~~naturally occurring [[endocannabinoids]] in the body~~.		=== Pharmacology ===
			Synthetic cannabinoids like CUMYL-PICA act as agonists at the [[cannabinoid receptor]]s, primarily the [[CB1 receptor]] and [[CB2 receptor]]. These receptors are part of the [[endocannabinoid system]], which plays a role in regulating mood, memory, appetite, and pain sensation. The binding affinity and efficacy of CUMYL-PICA at these receptors can lead to effects similar to those of THC, but often with greater potency and unpredictability.

	==~~Legal Status~~==		=== Effects and Risks ===
			The effects of CUMYL-PICA can include euphoria, altered perception, and relaxation. However, due to its high potency, it can also cause adverse effects such as anxiety, paranoia, tachycardia, and in severe cases, psychosis or seizures. The use of synthetic cannabinoids has been associated with numerous health risks, and their legal status varies by region.

	The legal status of CUMYL-PICA varies ~~by country~~. In ~~some~~ countries, it is classified as a controlled substance due to its potential for abuse and ~~the health risks associated with its~~ use. ~~In other countries, it is~~ legal ~~to possess~~ and ~~use CUMYL-PICA for research purposes~~.		=== Legal Status ===
			The legal status of CUMYL-PICA varies worldwide. In many countries, it is classified as a controlled substance due to its potential for abuse and lack of accepted medical use. Regulatory agencies continue to monitor and update the legal status of synthetic cannabinoids as new compounds are identified and their effects are better understood.
	~~==See Also==~~

			== Related Pages ==
	* [[Synthetic cannabinoids]]		* [[Synthetic cannabinoids]]
	* [[Cannabinoid receptor]]		* [[Cannabinoid receptor]]
			* [[Tetrahydrocannabinol]]
	* [[Endocannabinoid system]]		* [[Endocannabinoid system]]

	~~==References==~~

	~~<references />~~

	[[Category:Synthetic cannabinoids]]		[[Category:Synthetic cannabinoids]]
	~~[[Category:Indoles]]~~
	~~[[Category:CB1 receptor agonists]]~~
	~~[[Category:CB2 receptor agonists]]~~

	~~{{stub}}~~
	~~{{No image}}~~

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'''CUMYL-PICA''' is a compound that belongs to the class of [[drug]]s known as [[synthetic cannabinoids]]. It is a potent [[agonist]] of the [[CB1 receptor]] and [[CB2 receptor]], which are part of the [[endocannabinoid system]] in the human body. CUMYL-PICA is often used in scientific research, but it has also been found in synthetic cannabis products sold for recreational use.

==Chemistry==

CUMYL-PICA is a derivative of [[indole]] and is structurally related to other synthetic cannabinoids such as [[5F-PB-22]] and [[BB-22]]. It has a cumyl group, which is a functional group consisting of a phenyl group attached to a tert-butyl group, attached to the indole ring through an amide linkage. The specific name CUMYL-PICA refers to the particular structure of this compound, where PICA stands for "PIndoleCArboxamide".

==Pharmacology==

As an agonist of the CB1 and CB2 receptors, CUMYL-PICA can produce effects similar to those of [[cannabis (drug)|cannabis]]. However, due to its synthetic nature and the potential for variations in its chemical structure, the effects of CUMYL-PICA can be unpredictable and potentially harmful. The exact mechanisms of action of CUMYL-PICA are not fully understood, but it is thought to work by mimicking the effects of naturally occurring [[endocannabinoids]] in the body.

==Legal Status==

The legal status of CUMYL-PICA varies by country. In some countries, it is classified as a controlled substance due to its potential for abuse and the health risks associated with its use. In other countries, it is legal to possess and use CUMYL-PICA for research purposes.

==See Also==

* [[Synthetic cannabinoids]]
* [[Cannabinoid receptor]]
* [[Endocannabinoid system]]

==References==

<references />

[[Category:Synthetic cannabinoids]]
[[Category:Indoles]]
[[Category:CB1 receptor agonists]]
[[Category:CB2 receptor agonists]]

{{stub}}

CUMYL-PICA - Revision history

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