https://wikimd.org/index.php?action=history&feed=atom&title=COX10 COX10 - Revision history 2026-04-27T04:10:59Z Revision history for this page on the wiki MediaWiki 1.44.2 https://wikimd.org/index.php?title=COX10&diff=6499653&oldid=prev Prab: CSV import 2025-03-17T05:54:59Z <p>CSV import</p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 05:54, 17 March 2025</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l30">Line 30:</td> <td colspan="2" class="diff-lineno">Line 30:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{medicine-stub}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{medicine-stub}}</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{No image}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{No image}}</div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">__NOINDEX__</ins></div></td></tr> </table> Prab https://wikimd.org/index.php?title=COX10&diff=6216025&oldid=prev Prab: CSV import 2025-02-10T09:07:40Z <p>CSV import</p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 09:07, 10 February 2025</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l29">Line 29:</td> <td colspan="2" class="diff-lineno">Line 29:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{medicine-stub}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{medicine-stub}}</div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">{{No image}}</ins></div></td></tr> </table> Prab https://wikimd.org/index.php?title=COX10&diff=5377756&oldid=prev Prab: CSV import 2024-03-09T21:01:52Z <p>CSV import</p> <p><b>New page</b></p><div>&#039;&#039;&#039;COX10&#039;&#039;&#039; also known as &#039;&#039;&#039;Cytochrome c oxidase assembly factor heme A:farnesyltransferase COX10&#039;&#039;&#039; is a protein that in humans is encoded by the COX10 gene. It is involved in the final stages of the mitochondrial electron transport chain, specifically in the synthesis of heme A, a component of cytochrome c oxidase (COX).<br /> <br /> == Function ==<br /> <br /> [[COX10]] is a mitochondrial protein involved in the biosynthesis of heme A, a prosthetic group of [[cytochrome c oxidase]] (COX). COX is the terminal enzyme of the mitochondrial respiratory chain and is responsible for the transfer of electrons from cytochrome c to oxygen. COX10 catalyzes the conversion of protoheme IX (heme B) to heme O, the penultimate step in the biosynthesis of heme A.<br /> <br /> == Clinical significance ==<br /> <br /> Mutations in the COX10 gene have been associated with [[mitochondrial complex IV deficiency]], a disorder of the mitochondrial respiratory chain with heterogeneous clinical manifestations, ranging from isolated [[myopathy]] to severe multisystem disease affecting several tissues and organs.<br /> <br /> == Structure ==<br /> <br /> The COX10 protein is a member of the heme A:farnesyltransferase family. It is a multi-pass membrane protein that is located in the inner mitochondrial membrane. The protein is predicted to have 8 transmembrane domains.<br /> <br /> == See also ==<br /> <br /> * [[Cytochrome c oxidase]]<br /> * [[Mitochondrial complex IV deficiency]]<br /> * [[Myopathy]]<br /> <br /> == References ==<br /> <br /> {{Reflist}}<br /> <br /> [[Category:Human proteins]]<br /> [[Category:Mitochondrial proteins]]<br /> [[Category:Enzymes]]<br /> [[Category:Genes]]<br /> <br /> {{medicine-stub}}</div> Prab