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	<title>CMKLR1 - Revision history</title>
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	<updated>2026-04-22T07:22:30Z</updated>
	<subtitle>Revision history for this page on the wiki</subtitle>
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	<entry>
		<id>https://wikimd.com/index.php?title=CMKLR1&amp;diff=6499505&amp;oldid=prev</id>
		<title>Prab: CSV import</title>
		<link rel="alternate" type="text/html" href="https://wikimd.com/index.php?title=CMKLR1&amp;diff=6499505&amp;oldid=prev"/>
		<updated>2025-03-17T05:49:24Z</updated>

		<summary type="html">&lt;p&gt;CSV import&lt;/p&gt;
&lt;table style=&quot;background-color: #fff; color: #202122;&quot; data-mw=&quot;interface&quot;&gt;
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				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 05:49, 17 March 2025&lt;/td&gt;
				&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot; id=&quot;mw-diff-left-l34&quot;&gt;Line 34:&lt;/td&gt;
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&lt;/table&gt;</summary>
		<author><name>Prab</name></author>
	</entry>
	<entry>
		<id>https://wikimd.com/index.php?title=CMKLR1&amp;diff=6215892&amp;oldid=prev</id>
		<title>Prab: CSV import</title>
		<link rel="alternate" type="text/html" href="https://wikimd.com/index.php?title=CMKLR1&amp;diff=6215892&amp;oldid=prev"/>
		<updated>2025-02-10T09:03:10Z</updated>

		<summary type="html">&lt;p&gt;CSV import&lt;/p&gt;
&lt;table style=&quot;background-color: #fff; color: #202122;&quot; data-mw=&quot;interface&quot;&gt;
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				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;← Older revision&lt;/td&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 09:03, 10 February 2025&lt;/td&gt;
				&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot; id=&quot;mw-diff-left-l33&quot;&gt;Line 33:&lt;/td&gt;
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&lt;/table&gt;</summary>
		<author><name>Prab</name></author>
	</entry>
	<entry>
		<id>https://wikimd.com/index.php?title=CMKLR1&amp;diff=5300004&amp;oldid=prev</id>
		<title>Prab: CSV import</title>
		<link rel="alternate" type="text/html" href="https://wikimd.com/index.php?title=CMKLR1&amp;diff=5300004&amp;oldid=prev"/>
		<updated>2024-02-25T22:16:17Z</updated>

		<summary type="html">&lt;p&gt;CSV import&lt;/p&gt;
&lt;p&gt;&lt;b&gt;New page&lt;/b&gt;&lt;/p&gt;&lt;div&gt;&amp;#039;&amp;#039;&amp;#039;CMKLR1&amp;#039;&amp;#039;&amp;#039; (Chemokine-like receptor 1) is a [[protein]] that in humans is encoded by the &amp;#039;&amp;#039;CMKLR1&amp;#039;&amp;#039; [[gene]]. It is also known as ChemR23, DEZ, or ChemerinR. CMKLR1 is a member of the [[G protein-coupled receptor]] family, and it has been implicated in various biological processes, including [[inflammation]], [[adipogenesis]], and [[cardiovascular disease]].&lt;br /&gt;
&lt;br /&gt;
== Function ==&lt;br /&gt;
&lt;br /&gt;
CMKLR1 is a receptor for the chemoattractant protein [[Chemerin]], and it mediates its effects through [[G protein]]-coupled signaling pathways. The activation of CMKLR1 by Chemerin can lead to intracellular [[calcium]] release and the activation of the [[phosphatidylinositol 3-kinase]] pathway.&lt;br /&gt;
&lt;br /&gt;
In addition to its role in inflammation, CMKLR1 has been shown to play a role in the regulation of adipogenesis. It is expressed in [[adipose tissue]], and its activation can promote the differentiation of [[pre-adipocytes]] into mature adipocytes.&lt;br /&gt;
&lt;br /&gt;
== Clinical significance ==&lt;br /&gt;
&lt;br /&gt;
Alterations in the function or expression of CMKLR1 have been associated with various diseases. For example, increased expression of CMKLR1 has been observed in [[atherosclerotic]] plaques, suggesting a role in the development of [[cardiovascular disease]]. In addition, mutations in the &amp;#039;&amp;#039;CMKLR1&amp;#039;&amp;#039; gene have been linked to [[obesity]] and [[metabolic syndrome]].&lt;br /&gt;
&lt;br /&gt;
== See also ==&lt;br /&gt;
&lt;br /&gt;
* [[G protein-coupled receptor]]&lt;br /&gt;
* [[Chemerin]]&lt;br /&gt;
* [[Adipogenesis]]&lt;br /&gt;
* [[Cardiovascular disease]]&lt;br /&gt;
&lt;br /&gt;
== References ==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;references /&amp;gt;&lt;br /&gt;
&lt;br /&gt;
== External links ==&lt;br /&gt;
&lt;br /&gt;
* [https://www.ncbi.nlm.nih.gov/gene/1240 CMKLR1] at the [[National Center for Biotechnology Information]]&lt;br /&gt;
&lt;br /&gt;
[[Category:G protein-coupled receptors]]&lt;br /&gt;
[[Category:Human proteins]]&lt;br /&gt;
[[Category:Genes]]&lt;br /&gt;
&lt;br /&gt;
{{G protein-coupled receptors}}&lt;br /&gt;
{{Human chromosome 12 gene stubs}}&lt;br /&gt;
{{stub}}&lt;/div&gt;</summary>
		<author><name>Prab</name></author>
	</entry>
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