Prab: CSV import

2025-03-17T05:50:26Z

CSV import

← Older revision		Revision as of 05:50, 17 March 2025
Line 30:		Line 30:
	{{stub}}		{{stub}}
	{{No image}}		{{No image}}
			__NOINDEX__

Prab: CSV import

2025-02-10T09:00:22Z

CSV import

← Older revision		Revision as of 09:00, 10 February 2025
Line 29:		Line 29:

	{{stub}}		{{stub}}
			{{No image}}

Prab: CSV import

2024-02-20T05:40:27Z

CSV import

New page

'''CIOMS/RUCAM scale''' is a widely used and validated method for assessing causality in cases of suspected drug-induced liver injury (DILI) and herb-induced liver injury (HILI). The scale was developed by the Council for International Organizations of Medical Sciences (CIOMS) and the Roussel Uclaf Causality Assessment Method (RUCAM).

== Overview ==

The [[CIOMS/RUCAM scale]] is a structured, quantitative tool that provides a standardized method for assessing causality in cases of suspected DILI and HILI. It is based on a scoring system that takes into account the time to onset of the liver injury, the course of the injury after discontinuation of the drug or herb, risk factors, concomitant drugs, non-drug causes of the liver injury, and previous information about the hepatotoxicity of the drug or herb.

== Scoring System ==

The scoring system of the CIOMS/RUCAM scale ranges from -9 to +14. A score of less than 0 indicates that the drug or herb is "excluded" as a cause of the liver injury. A score of 1-2 is "unlikely", 3-5 is "possible", 6-8 is "probable", and >8 is "highly probable".

== Use in Clinical Practice ==

In clinical practice, the CIOMS/RUCAM scale is used to help determine whether a drug or herb is the likely cause of a patient's liver injury. This can be particularly useful in cases where the patient is taking multiple medications or supplements, and it is unclear which one may be responsible for the liver injury.

== Limitations ==

While the CIOMS/RUCAM scale is a valuable tool, it does have some limitations. For example, it may not be as accurate in cases of chronic liver injury, or in cases where the patient has taken multiple drugs or herbs that could potentially cause liver injury.

== See Also ==

* [[Drug-induced liver injury]]
* [[Herb-induced liver injury]]
* [[Council for International Organizations of Medical Sciences]]
* [[Roussel Uclaf Causality Assessment Method]]

[[Category:Medical scales]]
[[Category:Hepatology]]
[[Category:Pharmacology]]

{{stub}}

CIOMS/RUCAM scale - Revision history

Prab: CSV import

Prab: CSV import

Prab: CSV import