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	<title>CD5 - Revision history</title>
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	<updated>2026-04-25T23:00:12Z</updated>
	<subtitle>Revision history for this page on the wiki</subtitle>
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	<entry>
		<id>https://wikimd.org/index.php?title=CD5&amp;diff=6499361&amp;oldid=prev</id>
		<title>Prab: CSV import</title>
		<link rel="alternate" type="text/html" href="https://wikimd.org/index.php?title=CD5&amp;diff=6499361&amp;oldid=prev"/>
		<updated>2025-03-17T05:35:56Z</updated>

		<summary type="html">&lt;p&gt;CSV import&lt;/p&gt;
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				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;← Older revision&lt;/td&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 05:35, 17 March 2025&lt;/td&gt;
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&lt;/table&gt;</summary>
		<author><name>Prab</name></author>
	</entry>
	<entry>
		<id>https://wikimd.org/index.php?title=CD5&amp;diff=6215746&amp;oldid=prev</id>
		<title>Prab: CSV import</title>
		<link rel="alternate" type="text/html" href="https://wikimd.org/index.php?title=CD5&amp;diff=6215746&amp;oldid=prev"/>
		<updated>2025-02-10T08:57:57Z</updated>

		<summary type="html">&lt;p&gt;CSV import&lt;/p&gt;
&lt;table style=&quot;background-color: #fff; color: #202122;&quot; data-mw=&quot;interface&quot;&gt;
				&lt;col class=&quot;diff-marker&quot; /&gt;
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				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;← Older revision&lt;/td&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 08:57, 10 February 2025&lt;/td&gt;
				&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot; id=&quot;mw-diff-left-l29&quot;&gt;Line 29:&lt;/td&gt;
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		<author><name>Prab</name></author>
	</entry>
	<entry>
		<id>https://wikimd.org/index.php?title=CD5&amp;diff=5299682&amp;oldid=prev</id>
		<title>Prab: CSV import</title>
		<link rel="alternate" type="text/html" href="https://wikimd.org/index.php?title=CD5&amp;diff=5299682&amp;oldid=prev"/>
		<updated>2024-02-25T22:06:21Z</updated>

		<summary type="html">&lt;p&gt;CSV import&lt;/p&gt;
&lt;p&gt;&lt;b&gt;New page&lt;/b&gt;&lt;/p&gt;&lt;div&gt;&amp;#039;&amp;#039;&amp;#039;CD5&amp;#039;&amp;#039;&amp;#039; is a [[protein]] that in humans is encoded by the &amp;#039;&amp;#039;CD5&amp;#039;&amp;#039; [[gene]]. CD5 is a member of the [[scavenger receptor cysteine-rich (SRCR) superfamily]] and is predominantly expressed in [[T cell]]s and [[B cell]]s, which are both types of [[white blood cells]]. It plays a role in the immune system&amp;#039;s response to disease and infection.&lt;br /&gt;
&lt;br /&gt;
== Structure ==&lt;br /&gt;
CD5 is a type 1 [[transmembrane protein]] that contains three extracellular [[SRCR domain|SRCR domains]], a transmembrane domain, and a short cytoplasmic tail. The SRCR domains are involved in protein-protein interactions, and the cytoplasmic tail interacts with intracellular proteins to mediate signal transduction.&lt;br /&gt;
&lt;br /&gt;
== Function ==&lt;br /&gt;
CD5 plays a crucial role in the immune response. It is involved in the activation and differentiation of T cells and B cells. CD5 acts as a negative regulator of these cells, helping to prevent overactive immune responses and autoimmune diseases. It does this by inhibiting the signaling pathways that lead to cell activation and proliferation.&lt;br /&gt;
&lt;br /&gt;
== Clinical significance ==&lt;br /&gt;
Alterations in the number of CD5+ B cells have been associated with various [[autoimmune diseases]], including [[rheumatoid arthritis]], [[systemic lupus erythematosus]], and [[Sjögren&amp;#039;s syndrome]]. In addition, CD5 is a marker for certain types of [[lymphoma]] and [[leukemia]], including [[chronic lymphocytic leukemia]] and [[mantle cell lymphoma]]. &lt;br /&gt;
&lt;br /&gt;
== See also ==&lt;br /&gt;
* [[Cluster of differentiation]]&lt;br /&gt;
* [[T cell]]&lt;br /&gt;
* [[B cell]]&lt;br /&gt;
* [[Autoimmune disease]]&lt;br /&gt;
* [[Lymphoma]]&lt;br /&gt;
* [[Leukemia]]&lt;br /&gt;
&lt;br /&gt;
== References ==&lt;br /&gt;
&amp;lt;references /&amp;gt;&lt;br /&gt;
&lt;br /&gt;
[[Category:Proteins]]&lt;br /&gt;
[[Category:Genes]]&lt;br /&gt;
[[Category:Immunology]]&lt;br /&gt;
[[Category:Autoimmune diseases]]&lt;br /&gt;
[[Category:Lymphoma]]&lt;br /&gt;
[[Category:Leukemia]]&lt;br /&gt;
&lt;br /&gt;
{{stub}}&lt;/div&gt;</summary>
		<author><name>Prab</name></author>
	</entry>
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