https://wikimd.com/index.php?action=history&feed=atom&title=CD48 CD48 - Revision history 2026-04-24T17:53:40Z Revision history for this page on the wiki MediaWiki 1.44.2 https://wikimd.com/index.php?title=CD48&diff=6500770&oldid=prev Prab: CSV import 2025-03-17T06:48:28Z <p>CSV import</p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 06:48, 17 March 2025</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l29">Line 29:</td> <td colspan="2" class="diff-lineno">Line 29:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{medicine-stub}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{medicine-stub}}</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{No image}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{No image}}</div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">__NOINDEX__</ins></div></td></tr> </table> Prab https://wikimd.com/index.php?title=CD48&diff=6215708&oldid=prev Prab: CSV import 2025-02-10T08:57:00Z <p>CSV import</p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 08:57, 10 February 2025</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l28">Line 28:</td> <td colspan="2" class="diff-lineno">Line 28:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[[Category:Medical terminology]]</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[[Category:Medical terminology]]</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{medicine-stub}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{medicine-stub}}</div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">{{No image}}</ins></div></td></tr> </table> Prab https://wikimd.com/index.php?title=CD48&diff=5377982&oldid=prev Prab: CSV import 2024-03-09T21:15:32Z <p>CSV import</p> <p><b>New page</b></p><div>&#039;&#039;&#039;CD48&#039;&#039;&#039; is a [[protein]] that in humans is encoded by the &#039;&#039;&#039;CD48&#039;&#039;&#039; [[gene]]. It is a member of the [[SLAM family]] of [[immunological]] transmembrane proteins, and functions as a high-affinity [[ligand]] for the [[natural killer cell]] inhibitory receptor [[CD244]].<br /> <br /> == Structure ==<br /> The CD48 protein is a [[glycoprotein]] that exists on the surface of [[lymphocytes]] and other [[immune cells]], [[platelets]], and [[endothelial cells]]. It is anchored to the cell membrane through a [[glycosylphosphatidylinositol]] (GPI) link. The protein is approximately 45 [[kDa]] in size and is composed of an extracellular domain, a transmembrane domain, and a short cytoplasmic tail.<br /> <br /> == Function ==<br /> CD48 plays a crucial role in the [[immune response]] and the regulation of [[immune cell]] activation. It interacts with [[CD2]] to regulate [[T cell]] activation and [[cytokine]] production. CD48 also binds to [[CD244]] on natural killer cells, modulating their activity in response to [[pathogen]]s and [[tumor cells]].<br /> <br /> == Clinical significance ==<br /> Alterations in CD48 expression or function have been associated with various [[disease]]s. Overexpression of CD48 has been observed in certain types of [[cancer]], including [[leukemia]] and [[lymphoma]], and is associated with poor prognosis. CD48 is also implicated in [[autoimmune diseases]], such as [[rheumatoid arthritis]] and [[lupus]], where it is thought to contribute to the inappropriate activation of the immune system.<br /> <br /> == Research ==<br /> CD48 is a target of interest in the development of [[immunotherapy]] treatments for cancer and autoimmune diseases. Inhibitors of CD48 are being investigated for their potential to modulate the immune response and improve patient outcomes.<br /> <br /> == See also ==<br /> * [[Cluster of differentiation]]<br /> * [[Immunology]]<br /> * [[Natural killer cell]]<br /> * [[Autoimmune disease]]<br /> * [[Cancer immunotherapy]]<br /> <br /> == References ==<br /> &lt;references /&gt;<br /> <br /> [[Category:Proteins]]<br /> [[Category:Immunology]]<br /> [[Category:Genes]]<br /> [[Category:Medical terminology]]<br /> {{medicine-stub}}</div> Prab