https://wikimd.com/index.php?action=history&feed=atom&title=CD2 CD2 - Revision history 2026-04-24T09:12:46Z Revision history for this page on the wiki MediaWiki 1.44.2 https://wikimd.com/index.php?title=CD2&diff=6499331&oldid=prev Prab: CSV import 2025-03-17T05:34:24Z <p>CSV import</p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 05:34, 17 March 2025</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l27">Line 27:</td> <td colspan="2" class="diff-lineno">Line 27:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{stub}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{stub}}</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{No image}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{No image}}</div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">__NOINDEX__</ins></div></td></tr> </table> Prab https://wikimd.com/index.php?title=CD2&diff=6213406&oldid=prev Prab: CSV import 2025-02-10T07:35:44Z <p>CSV import</p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 07:35, 10 February 2025</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l26">Line 26:</td> <td colspan="2" class="diff-lineno">Line 26:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{stub}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{stub}}</div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">{{No image}}</ins></div></td></tr> </table> Prab https://wikimd.com/index.php?title=CD2&diff=5302168&oldid=prev Prab: CSV import 2024-02-25T23:25:06Z <p>CSV import</p> <p><b>New page</b></p><div>&#039;&#039;&#039;CD2&#039;&#039;&#039; (Cluster of Differentiation 2) is a cell adhesion molecule found on the surface of T cells and natural killer (NK) cells. It has been identified as a target for immunosuppressive therapies and plays a crucial role in the immune response and T cell activation.<br /> <br /> == Structure ==<br /> CD2 is a transmembrane glycoprotein that belongs to the immunoglobulin superfamily. It consists of an extracellular domain, a transmembrane domain, and a cytoplasmic tail. The extracellular domain is responsible for binding to its ligand, CD58, while the cytoplasmic tail is involved in signal transduction.<br /> <br /> == Function ==<br /> CD2 plays a key role in the immune response by mediating adhesion and signal transduction in T cells and NK cells. It interacts with CD58 on antigen-presenting cells, leading to the activation of T cells and the initiation of the immune response. CD2 also plays a role in the formation of the immunological synapse, a specialized contact area between T cells and antigen-presenting cells where signal transduction occurs.<br /> <br /> == Clinical significance ==<br /> Alterations in CD2 expression or function have been associated with various diseases, including autoimmune disorders and cancers. In autoimmune diseases, abnormal CD2 expression can lead to the activation of autoreactive T cells, contributing to tissue damage. In cancers, particularly lymphomas and leukemias, CD2 can be overexpressed, promoting tumor growth and survival.<br /> <br /> == Therapeutic potential ==<br /> Due to its role in T cell activation, CD2 has been identified as a target for immunosuppressive therapies. Drugs that block CD2-CD58 interaction can inhibit T cell activation, potentially reducing the severity of autoimmune diseases or preventing transplant rejection.<br /> <br /> [[Category:Immunology]]<br /> [[Category:Cell biology]]<br /> [[Category:Proteins]]<br /> [[Category:Medical terminology]]<br /> <br /> See also:<br /> * [[T cell]]<br /> * [[Natural killer cell]]<br /> * [[Immunoglobulin superfamily]]<br /> * [[CD58]]<br /> * [[Immunological synapse]]<br /> <br /> {{stub}}</div> Prab