https://wikimd.org/index.php?action=history&feed=atom&title=Birtoxin 2026-04-27T06:16:03Z Revision history for this page on the wiki MediaWiki 1.44.2 https://wikimd.org/index.php?title=Birtoxin&diff=6336025&oldid=prev 2025-02-20T01:43:37Z

<p>CSV import</p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 01:43, 20 February 2025</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l26">Line 26:</td> <td colspan="2" class="diff-lineno">Line 26:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{toxin-stub}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{toxin-stub}}</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{medicine-stub}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{medicine-stub}}</div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">&lt;gallery&gt;</ins></div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">File:Parabuthus transvaalicus (male).jpg|Birtoxin</ins></div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">&lt;/gallery&gt;</ins></div></td></tr> </table>

Prab https://wikimd.org/index.php?title=Birtoxin&diff=5382035&oldid=prev 2024-03-10T19:35:04Z

<p>CSV import</p> <p><b>New page</b></p><div>&#039;&#039;&#039;Birtoxin&#039;&#039;&#039; is a potent [[neurotoxin]] found in the venom of the [[African spitting scorpion]] (&#039;&#039;Parabuthus transvaalicus&#039;&#039;). It is a member of the [[alpha-KTx]] family of toxins, which are known for their ability to block [[voltage-gated potassium channels]].<br /> <br /> ==Structure and Function==<br /> <br /> Birtoxin is a small [[protein]] composed of 35 [[amino acids]]. It has a compact, stable structure that is maintained by three [[disulfide bond]]s. This structure allows it to bind tightly to voltage-gated potassium channels, blocking the flow of [[potassium ions]] and disrupting normal [[neuronal]] function.<br /> <br /> The exact mechanism by which birtoxin blocks these channels is not fully understood. However, it is thought to bind to a specific site on the channel, preventing it from opening in response to changes in [[membrane potential]].<br /> <br /> ==Clinical Significance==<br /> <br /> The venom of the African spitting scorpion, which contains birtoxin, can cause severe [[pain]], [[swelling]], and [[paralysis]] in humans. In rare cases, it can be fatal. However, the venom is also of interest to medical researchers, as it could potentially be used to develop new treatments for a variety of [[neurological disorders]], including [[epilepsy]] and [[chronic pain]].<br /> <br /> ==Research and Therapeutic Potential==<br /> <br /> Research into the properties of birtoxin and other scorpion venom toxins is ongoing. Some studies suggest that these toxins could be used to create highly selective drugs that target specific types of voltage-gated potassium channels. This could potentially lead to new treatments for a variety of conditions, including [[heart disease]], [[diabetes]], and certain types of [[cancer]].<br /> <br /> ==See Also==<br /> * [[Scorpion venom]]<br /> * [[Neurotoxin]]<br /> * [[Voltage-gated potassium channel]]<br /> <br /> [[Category:Toxins]]<br /> [[Category:Neurotoxins]]<br /> [[Category:Scorpion venoms]]<br /> <br /> {{toxin-stub}}<br /> {{medicine-stub}}</div>

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