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2025-02-20T00:51:56Z

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			<gallery caption="Bile acid">
			File:Cholic Acid vs Other Bile Acids.svg\|Cholic Acid vs Other Bile Acids
			File:Cholic acid.svg\|Cholic acid
			File:Glycocholsäure.svg\|Glycocholic acid
			File:Taurocholic acid.svg\|Taurocholic acid
			File:Deoxycholic acid.svg\|Deoxycholic acid
			File:Chenodeoxycholic acid.svg\|Chenodeoxycholic acid
			File:Glycochenodeoxycholic acid.svg\|Glycochenodeoxycholic acid
			File:Taurochenodeoxycholic acid.svg\|Taurochenodeoxycholic acid
			File:Lithocholic acid acsv.svg\|Lithocholic acid
			File:Steroid lettering numbering.svg\|Steroid lettering numbering
			</gallery>

Prab: CSV import

2024-03-03T13:49:49Z

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'''Bile Acid''' is a type of [[acid]] produced by the [[liver]] and stored in the [[gallbladder]]. It plays a crucial role in the [[digestion]] and absorption of [[fat]] and fat-soluble [[vitamin]]s in the [[small intestine]].

== Production and Composition ==
Bile acids are synthesized from [[cholesterol]] in the liver through a process known as [[bile acid synthesis]]. The primary bile acids, [[cholic acid]] and [[chenodeoxycholic acid]], are conjugated with [[glycine]] or [[taurine]] to form bile salts, which are then secreted into the bile ducts.

== Function ==
The main function of bile acids is to facilitate the digestion and absorption of dietary fats and fat-soluble vitamins in the small intestine. They act as [[emulsifier]]s, breaking down large fat globules into smaller droplets that can be easily digested by [[lipase]], an enzyme produced by the [[pancreas]]. Bile acids also stimulate the secretion of [[bile]] and [[pancreatic juice]], both of which are essential for digestion.

== Regulation ==
The production and secretion of bile acids are tightly regulated by the body. The [[enterohepatic circulation]] plays a key role in this regulation. When bile acids are reabsorbed in the small intestine, they are transported back to the liver, where they inhibit their own synthesis. This feedback mechanism ensures that the body maintains a constant pool of bile acids.

== Clinical Significance ==
Abnormalities in bile acid metabolism can lead to several health conditions. For instance, a deficiency in bile acids can result in [[fat malabsorption]] and vitamin deficiencies. On the other hand, excessive bile acids can cause [[gallstone]] formation. Moreover, certain diseases such as [[primary biliary cirrhosis]] and [[primary sclerosing cholangitis]] are associated with impaired bile acid production and secretion.

[[Category:Biochemistry]]
[[Category:Digestive system]]
[[Category:Hepatology]]
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{{digestive-system-stub}}
{{medicine-stub}}

Bile acid - Revision history

Prab: CSV import

Prab: CSV import