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← Older revision		Revision as of 17:10, 4 April 2025
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	[[File:Mouse_with_spinal_muscular_atrophy.jpg\|Mouse with spinal muscular atrophy\|thumb]] '''Atrophy''' refers to the partial or complete wasting away of a part of the body. This condition is characterized by a reduction in the size of the muscle or organ involved, often leading to a decrease in function. Atrophy can result from a variety of causes, including prolonged immobility, aging, malnutrition, certain diseases, and injuries. It is a process that can affect different tissues and organs within the body, such as muscles, brain tissue, and bones.		{{SI}}
			{{Infobox medical condition
			\| name = Atrophy
			\| image = [[File:Mouse_with_spinal_muscular_atrophy.jpg\|250px]]
			\| caption = A mouse with [[spinal muscular atrophy]], a condition that causes muscle atrophy
			\| field = [[Neurology]], [[Orthopedics]]
			\| symptoms = [[Muscle weakness]], [[muscle wasting]]
			\| complications = [[Disability]], [[loss of function]]
			\| onset = Varies depending on cause
			\| duration = Can be [[chronic]] or [[acute]]
			\| causes = [[Disuse]], [[denervation]], [[malnutrition]], [[disease]]
			\| risks = [[Immobilization]], [[aging]], [[neurological disorders]]
			\| diagnosis = [[Physical examination]], [[imaging studies]], [[biopsy]]
			\| differential = [[Cachexia]], [[sarcopenia]], [[dystrophy]]
			\| prevention = [[Exercise]], [[physical therapy]], [[nutrition]]
			\| treatment = [[Physical therapy]], [[occupational therapy]], [[surgery]]
			\| prognosis = Depends on underlying cause
			\| frequency = Common in [[elderly]] and [[immobilized]] individuals
			}}
			[[File:Mouse_with_spinal_muscular_atrophy.jpg\|Mouse with spinal muscular atrophy\|left\|thumb]] '''Atrophy''' refers to the partial or complete wasting away of a part of the body. This condition is characterized by a reduction in the size of the muscle or organ involved, often leading to a decrease in function. Atrophy can result from a variety of causes, including prolonged immobility, aging, malnutrition, certain diseases, and injuries. It is a process that can affect different tissues and organs within the body, such as muscles, brain tissue, and bones.
	==Causes==		==Causes==
	Atrophy can be caused by several factors, which can be broadly classified into two categories: disuse and disease.		Atrophy can be caused by several factors, which can be broadly classified into two categories: disuse and disease.

	===Disuse Atrophy===		===Disuse Atrophy===
	Disuse atrophy occurs when there is a reduction in physical activity or when a body part is not used for a long period. This type of atrophy is commonly seen in people who have been bedridden or in those who wear casts for extended periods due to fractures. Muscles are the primary tissues affected by disuse atrophy.		Disuse atrophy occurs when there is a reduction in physical activity or when a body part is not used for a long period. This type of atrophy is commonly seen in people who have been bedridden or in those who wear casts for extended periods due to fractures. Muscles are the primary tissues affected by disuse atrophy.

	===Disease-Related Atrophy===		===Disease-Related Atrophy===
	Disease-related atrophy can result from various conditions, including:		Disease-related atrophy can result from various conditions, including:
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	* [[Pathological atrophy]]: Diseases such as [[cancer]], [[AIDS]], and [[heart failure]] can lead to a severe loss of muscle mass and function, a condition known as cachexia.		* [[Pathological atrophy]]: Diseases such as [[cancer]], [[AIDS]], and [[heart failure]] can lead to a severe loss of muscle mass and function, a condition known as cachexia.
	* [[Hormonal atrophy]]: Changes in hormone levels, particularly in estrogen and testosterone, can lead to atrophy. For example, menopause can cause vaginal atrophy, and low testosterone levels can lead to muscle atrophy in men.		* [[Hormonal atrophy]]: Changes in hormone levels, particularly in estrogen and testosterone, can lead to atrophy. For example, menopause can cause vaginal atrophy, and low testosterone levels can lead to muscle atrophy in men.

	==Symptoms==		==Symptoms==
	The primary symptom of atrophy is a noticeable decrease in the size or mass of the muscle or organ. Other symptoms may include weakness, reduced function, and decreased stamina. In cases of brain atrophy, symptoms might include memory loss, difficulty in thinking, and changes in behavior.		The primary symptom of atrophy is a noticeable decrease in the size or mass of the muscle or organ. Other symptoms may include weakness, reduced function, and decreased stamina. In cases of brain atrophy, symptoms might include memory loss, difficulty in thinking, and changes in behavior.

	==Diagnosis==		==Diagnosis==
	Diagnosis of atrophy involves a physical examination and a review of the patient's medical history. Imaging tests such as [[MRI]]s, [[CT scans]], and [[X-rays]] can be used to assess the extent of muscle or organ atrophy. In some cases, a biopsy may be performed to examine the tissue more closely.		Diagnosis of atrophy involves a physical examination and a review of the patient's medical history. Imaging tests such as [[MRI]]s, [[CT scans]], and [[X-rays]] can be used to assess the extent of muscle or organ atrophy. In some cases, a biopsy may be performed to examine the tissue more closely.

	==Treatment==		==Treatment==
	Treatment for atrophy aims to address the underlying cause of the condition. In cases of disuse atrophy, physical therapy and regular exercise can help restore muscle strength and mass. For disease-related atrophy, treatment may involve managing the underlying disease. Nutritional support and medications may also be recommended to help improve muscle mass and function.		Treatment for atrophy aims to address the underlying cause of the condition. In cases of disuse atrophy, physical therapy and regular exercise can help restore muscle strength and mass. For disease-related atrophy, treatment may involve managing the underlying disease. Nutritional support and medications may also be recommended to help improve muscle mass and function.

	==Prevention==		==Prevention==
	Preventing atrophy involves maintaining a healthy lifestyle, including regular exercise and a balanced diet. For individuals with mobility issues, engaging in physical therapy or light exercises as recommended by a healthcare provider can help prevent disuse atrophy. Additionally, managing chronic diseases effectively can help prevent disease-related atrophy.		Preventing atrophy involves maintaining a healthy lifestyle, including regular exercise and a balanced diet. For individuals with mobility issues, engaging in physical therapy or light exercises as recommended by a healthcare provider can help prevent disuse atrophy. Additionally, managing chronic diseases effectively can help prevent disease-related atrophy.

	[[Category:Medical conditions]]		[[Category:Medical conditions]]
	[[Category:Pathophysiology]]		[[Category:Pathophysiology]]
	{{medicine-stub}}		{{medicine-stub}}

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2024-04-23T21:50:33Z

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[[File:Mouse_with_spinal_muscular_atrophy.jpg|Mouse with spinal muscular atrophy|thumb]] '''Atrophy''' refers to the partial or complete wasting away of a part of the body. This condition is characterized by a reduction in the size of the muscle or organ involved, often leading to a decrease in function. Atrophy can result from a variety of causes, including prolonged immobility, aging, malnutrition, certain diseases, and injuries. It is a process that can affect different tissues and organs within the body, such as muscles, brain tissue, and bones.

==Causes==
Atrophy can be caused by several factors, which can be broadly classified into two categories: disuse and disease.

===Disuse Atrophy===
Disuse atrophy occurs when there is a reduction in physical activity or when a body part is not used for a long period. This type of atrophy is commonly seen in people who have been bedridden or in those who wear casts for extended periods due to fractures. Muscles are the primary tissues affected by disuse atrophy.

===Disease-Related Atrophy===
Disease-related atrophy can result from various conditions, including:
* [[Neurogenic atrophy]]: This occurs when there is damage to a nerve that connects to the muscle. Diseases such as [[Amyotrophic Lateral Sclerosis (ALS)]] and [[poliomyelitis]] can lead to neurogenic atrophy.
* [[Pathological atrophy]]: Diseases such as [[cancer]], [[AIDS]], and [[heart failure]] can lead to a severe loss of muscle mass and function, a condition known as cachexia.
* [[Hormonal atrophy]]: Changes in hormone levels, particularly in estrogen and testosterone, can lead to atrophy. For example, menopause can cause vaginal atrophy, and low testosterone levels can lead to muscle atrophy in men.

==Symptoms==
The primary symptom of atrophy is a noticeable decrease in the size or mass of the muscle or organ. Other symptoms may include weakness, reduced function, and decreased stamina. In cases of brain atrophy, symptoms might include memory loss, difficulty in thinking, and changes in behavior.

==Diagnosis==
Diagnosis of atrophy involves a physical examination and a review of the patient's medical history. Imaging tests such as [[MRI]]s, [[CT scans]], and [[X-rays]] can be used to assess the extent of muscle or organ atrophy. In some cases, a biopsy may be performed to examine the tissue more closely.

==Treatment==
Treatment for atrophy aims to address the underlying cause of the condition. In cases of disuse atrophy, physical therapy and regular exercise can help restore muscle strength and mass. For disease-related atrophy, treatment may involve managing the underlying disease. Nutritional support and medications may also be recommended to help improve muscle mass and function.

==Prevention==
Preventing atrophy involves maintaining a healthy lifestyle, including regular exercise and a balanced diet. For individuals with mobility issues, engaging in physical therapy or light exercises as recommended by a healthcare provider can help prevent disuse atrophy. Additionally, managing chronic diseases effectively can help prevent disease-related atrophy.

[[Category:Medical conditions]]
[[Category:Pathophysiology]]
{{medicine-stub}}

Atrophy - Revision history

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