https://wikimd.com/index.php?action=history&feed=atom&title=Atrial_action_potential 2026-04-06T14:28:18Z Revision history for this page on the wiki MediaWiki 1.44.2 https://wikimd.com/index.php?title=Atrial_action_potential&diff=6498630&oldid=prev 2025-03-17T04:58:01Z

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Prab https://wikimd.com/index.php?title=Atrial_action_potential&diff=5326957&oldid=prev 2024-02-28T22:03:47Z

<p>CSV import</p> <p><b>New page</b></p><div>&#039;&#039;&#039;Atrial action potential&#039;&#039;&#039; refers to the electrical changes that occur in [[atrial myocytes]], which are the muscle cells of the [[atria]] in the heart. These changes are crucial for the initiation and propagation of the [[cardiac cycle]], which is the sequence of events that occur when the heart beats.<br /> <br /> == Overview ==<br /> <br /> The atrial action potential is initiated by the [[sinoatrial node]], the heart&#039;s natural pacemaker. This triggers a wave of depolarization that spreads through the atria, causing them to contract and pump blood into the [[ventricles]].<br /> <br /> == Phases of the Atrial Action Potential ==<br /> <br /> The atrial action potential consists of five phases, numbered 0 through 4.<br /> <br /> === Phase 0 ===<br /> <br /> Phase 0 is the rapid depolarization phase. It is initiated when the membrane potential reaches a certain threshold, causing voltage-gated [[sodium channels]] to open. This allows sodium ions to rush into the cell, causing the membrane potential to become positive.<br /> <br /> === Phase 1 ===<br /> <br /> Phase 1 is the initial repolarization phase. After the sodium channels close, voltage-gated [[potassium channels]] open. This allows potassium ions to leave the cell, causing the membrane potential to start to become negative again.<br /> <br /> === Phase 2 ===<br /> <br /> Phase 2 is the plateau phase. During this phase, calcium ions enter the cell through [[calcium channels]], balancing the outflow of potassium ions. This causes the membrane potential to remain relatively stable.<br /> <br /> === Phase 3 ===<br /> <br /> Phase 3 is the rapid repolarization phase. The calcium channels close and more potassium channels open, causing the membrane potential to become more negative.<br /> <br /> === Phase 4 ===<br /> <br /> Phase 4 is the resting phase. During this phase, the membrane potential is maintained at a stable negative value until the next action potential is initiated.<br /> <br /> == Clinical Significance ==<br /> <br /> Abnormalities in the atrial action potential can lead to [[arrhythmias]], which are irregular heart rhythms. For example, if the atrial action potential is too long, it can lead to atrial fibrillation, a condition in which the atria beat irregularly and out of sync with the ventricles.<br /> <br /> == See Also ==<br /> <br /> * [[Cardiac action potential]]<br /> * [[Ventricular action potential]]<br /> * [[Pacemaker potential]]<br /> <br /> [[Category:Cardiology]]<br /> [[Category:Electrophysiology]]<br /> {{Cardiology-stub}}<br /> {{Medicine-stub}}</div>

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