Prab at 14:44, 4 April 2025

2025-04-04T14:44:40Z

← Older revision		Revision as of 14:44, 4 April 2025
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			{{SI}}<br>
			{{Infobox medical condition
			\| name = Aortic dissection
			\| image = [[File:AoDissekt_scheme_StanfordB_en.png\|250px]]
			\| caption = Schematic of aortic dissection
			\| field = [[Cardiology]], [[Vascular surgery]]
			\| synonyms = Dissecting aneurysm
			\| symptoms = [[Severe chest pain]], [[back pain]], [[shortness of breath]], [[syncope]]
			\| complications = [[Aortic rupture]], [[organ failure]], [[stroke]], [[cardiac tamponade]]
			\| onset = Sudden
			\| duration = Can be acute or chronic
			\| types = [[Stanford type A]], [[Stanford type B]]
			\| causes = [[Hypertension]], [[connective tissue disorders]], [[trauma]], [[bicuspid aortic valve]]
			\| risks = [[Hypertension]], [[atherosclerosis]], [[genetic disorders]] (e.g., [[Marfan syndrome]], [[Ehlers-Danlos syndrome]])
			\| diagnosis = [[CT scan]], [[MRI]], [[transesophageal echocardiogram]]
			\| differential = [[Myocardial infarction]], [[pulmonary embolism]], [[pericarditis]]
			\| prevention = [[Blood pressure control]], [[smoking cessation]]
			\| treatment = [[Surgery]], [[medication]] (e.g., [[beta blockers]], [[vasodilators]])
			\| prognosis = Variable, depends on type and treatment
			\| frequency = 3 per 100,000 per year
			\| deaths = High mortality if untreated
			}}
	An aortic dissection represents a serious and often critical condition in which there is a progressive tear in the innermost layer (tunica intima) of the [[aorta]], the largest artery in the body. This tear allows blood to flow between the layers of the aortic wall, forcing the layers apart.		An aortic dissection represents a serious and often critical condition in which there is a progressive tear in the innermost layer (tunica intima) of the [[aorta]], the largest artery in the body. This tear allows blood to flow between the layers of the aortic wall, forcing the layers apart.
	[[File:Aortic dissection of DeBakey type I.png\|thumb\|Aortic dissection of DeBakey type I]]		[[File:Aortic dissection of DeBakey type I.png\|thumb\|left\|Aortic dissection of DeBakey type I]]
	== Pathophysiology ==		== Pathophysiology ==
	In an aortic dissection, blood penetrates the intima and enters the tunica media, the middle layer of the aortic wall. This leads to the formation of a "false lumen," a new, abnormal channel within the aortic wall. The process can progressively extend along the length of the aorta, potentially interfering with the branches of the aorta and leading to a range of complications.		In an aortic dissection, blood penetrates the intima and enters the tunica media, the middle layer of the aortic wall. This leads to the formation of a ""false lumen," a new, abnormal channel within the aortic wall. The process can progressively extend along the length of the aorta, potentially interfering with the branches of the aorta and leading to a range of complications.
			[[File:Dissecting aneurysm 01.jpg\|thumb\|left\|Dissecting aneurysm 01]]
	[[File:Dissecting aneurysm 01.jpg\|thumb\|Dissecting aneurysm 01]]
	== Risk Factors ==		== Risk Factors ==
	Key risk factors for aortic dissection include uncontrolled high blood pressure ([[hypertension]]), conditions that cause inflammation of the arteries (like [[vasculitis]]), certain genetic disorders such as [[Marfan syndrome]], and a history of heart surgery or procedures. Aging, [[smoking]], high cholesterol levels, and a family history of the condition also contribute to the risk.		Key risk factors for aortic dissection include uncontrolled high blood pressure ([[hypertension]]), conditions that cause inflammation of the arteries (like [[vasculitis]]), certain genetic disorders such as [[Marfan syndrome]], and a history of heart surgery or procedures. Aging, [[smoking]], high cholesterol levels, and a family history of the condition also contribute to the risk.

	== Clinical Presentation ==		== Clinical Presentation ==
	Symptoms of an aortic dissection can mimic those of other conditions, making it challenging to diagnose. The most common symptom is severe, sudden chest pain often described as tearing or ripping, radiating to the back. Other symptoms may include shortness of breath, loss of consciousness, weak or absent pulse in one arm, or leg pain or paralysis.		Symptoms of an aortic dissection can mimic those of other conditions, making it challenging to diagnose. The most common symptom is severe, sudden chest pain often described as tearing or ripping, radiating to the back. Other symptoms may include shortness of breath, loss of consciousness, weak or absent pulse in one arm, or leg pain or paralysis.

	== Diagnosis ==		== Diagnosis ==
	Diagnosis is often made based on clinical signs and symptoms, and is confirmed by imaging studies, such as computed tomography (CT) angiography, magnetic resonance imaging (MRI), or transesophageal echocardiography.		Diagnosis is often made based on clinical signs and symptoms, and is confirmed by imaging studies, such as computed tomography (CT) angiography, magnetic resonance imaging (MRI), or transesophageal echocardiography.

	== Treatment ==		== Treatment ==
	The treatment for aortic dissection depends on the location and extent of the dissection. Type A dissections, which involve the ascending aorta, are typically treated with emergency surgery due to their high risk of complications. Type B dissections, which occur distal to the subclavian artery, can often be managed medically with blood pressure control, although surgery may be needed in certain situations.		The treatment for aortic dissection depends on the location and extent of the dissection. Type A dissections, which involve the ascending aorta, are typically treated with emergency surgery due to their high risk of complications. Type B dissections, which occur distal to the subclavian artery, can often be managed medically with blood pressure control, although surgery may be needed in certain situations.

	== Prevention ==		== Prevention ==
	Preventive measures for aortic dissection largely involve managing risk factors. This includes controlling hypertension, treating conditions like vasculitis, and monitoring those with genetic conditions like Marfan syndrome. Additionally, individuals with a history of aortic dissection may require regular follow-up imaging to monitor the aorta.		Preventive measures for aortic dissection largely involve managing risk factors. This includes controlling hypertension, treating conditions like vasculitis, and monitoring those with genetic conditions like Marfan syndrome. Additionally, individuals with a history of aortic dissection may require regular follow-up imaging to monitor the aorta.

	~~== References ==~~
	~~# Nienaber, C. A., & Clough, R. E. (2015). Management of acute aortic dissection. The Lancet, 385(9970), 800-811.~~
	~~# Ramanath, V. S., Oh, J. K., Sundt, T. M., & Eagle, K. A. (2009). Acute aortic syndromes and thoracic aortic aneurysm. Mayo Clinic Proceedings, 84(5), 465-481.~~

	[[Category: Cardiology]]		[[Category: Cardiology]]
	[[Category: Medical Emergencies]]		[[Category: Medical Emergencies]]

Prab at 01:58, 17 May 2023

2023-05-17T01:58:15Z

New page

An aortic dissection represents a serious and often critical condition in which there is a progressive tear in the innermost layer (tunica intima) of the [[aorta]], the largest artery in the body. This tear allows blood to flow between the layers of the aortic wall, forcing the layers apart.
[[File:Aortic dissection of DeBakey type I.png|thumb|Aortic dissection of DeBakey type I]]
== Pathophysiology ==
In an aortic dissection, blood penetrates the intima and enters the tunica media, the middle layer of the aortic wall. This leads to the formation of a "false lumen," a new, abnormal channel within the aortic wall. The process can progressively extend along the length of the aorta, potentially interfering with the branches of the aorta and leading to a range of complications.

[[File:Dissecting aneurysm 01.jpg|thumb|Dissecting aneurysm 01]]
== Risk Factors ==
Key risk factors for aortic dissection include uncontrolled high blood pressure ([[hypertension]]), conditions that cause inflammation of the arteries (like [[vasculitis]]), certain genetic disorders such as [[Marfan syndrome]], and a history of heart surgery or procedures. Aging, [[smoking]], high cholesterol levels, and a family history of the condition also contribute to the risk.

== Clinical Presentation ==
Symptoms of an aortic dissection can mimic those of other conditions, making it challenging to diagnose. The most common symptom is severe, sudden chest pain often described as tearing or ripping, radiating to the back. Other symptoms may include shortness of breath, loss of consciousness, weak or absent pulse in one arm, or leg pain or paralysis.

== Diagnosis ==
Diagnosis is often made based on clinical signs and symptoms, and is confirmed by imaging studies, such as computed tomography (CT) angiography, magnetic resonance imaging (MRI), or transesophageal echocardiography.

== Treatment ==
The treatment for aortic dissection depends on the location and extent of the dissection. Type A dissections, which involve the ascending aorta, are typically treated with emergency surgery due to their high risk of complications. Type B dissections, which occur distal to the subclavian artery, can often be managed medically with blood pressure control, although surgery may be needed in certain situations.

== Prevention ==
Preventive measures for aortic dissection largely involve managing risk factors. This includes controlling hypertension, treating conditions like vasculitis, and monitoring those with genetic conditions like Marfan syndrome. Additionally, individuals with a history of aortic dissection may require regular follow-up imaging to monitor the aorta.

== References ==
# Nienaber, C. A., & Clough, R. E. (2015). Management of acute aortic dissection. The Lancet, 385(9970), 800-811.
# Ramanath, V. S., Oh, J. K., Sundt, T. M., & Eagle, K. A. (2009). Acute aortic syndromes and thoracic aortic aneurysm. Mayo Clinic Proceedings, 84(5), 465-481.

[[Category: Cardiology]]
[[Category: Medical Emergencies]]
[[Category: Vascular Diseases]]
[[Category: Aortic Dissection]]
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Aortic dissection - Revision history

Prab at 14:44, 4 April 2025

Prab at 01:58, 17 May 2023