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<p><b>New page</b></p><div>[[Image:Mass_versus_moles_of_iron_vs_gold.svg|Mass versus moles of iron vs gold|thumb]] '''Amount of substance''' is a [[standard]] in [[chemistry]] and [[physics]] that measures the quantity of [[particles]], such as [[atoms]], [[molecules]], or [[ions]], in a given sample of matter. It is one of the seven [[base quantities]] in the [[International System of Units]] (SI), and its SI unit is the [[mole]] (symbol: mol). The mole is defined by setting the fixed numerical value of the [[Avogadro constant]], N<sub>A</sub>, to be 6.022 140 76 × 10<sup>23</sup> entities per mole, and is one of the fundamental constants in [[science]].<br />
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==Definition==<br />
The amount of substance, symbol n, of a system is a measure of the number of specified elementary entities. An elementary entity may be an [[atom]], [[molecule]], [[ion]], [[electron]], any other particle, or a specified group of such particles. In terms of the mole, the amount of substance of a system is the measure of the number of entities compared to the number of atoms in 12 grams of carbon-12 (^12C), which is approximately 6.022 × 10<sup>23</sup> atoms.<br />
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==Measurement==<br />
The amount of substance is measured by its proportion to the mole. To determine the amount of substance in a sample, one can use the formula:<br />
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n = N / N<sub>A</sub><br />
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where n is the amount of substance in moles, N is the total number of entities in the sample, and N<sub>A</sub> is the Avogadro constant. This formula allows for the calculation of the amount of substance in a given sample when the total number of entities is known.<br />
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==Importance in Science==<br />
The concept of the amount of substance is crucial in both [[chemistry]] and [[physics]]. It allows scientists to quantify the amount of reactants and products in [[chemical reactions]] and to understand the relationships between different substances in a reaction. In [[physics]], the amount of substance is used in the study of [[gases]], through the [[ideal gas law]], and in the determination of the properties of materials.<br />
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==SI Unit==<br />
The SI unit for the amount of substance is the mole. The mole is a coherent SI unit that is indispensable in [[scientific calculations]], facilitating the expression of quantities like [[concentration]], [[stoichiometry]] in chemical equations, and the yield of reactions. The use of the mole as a unit helps standardize measurements across different laboratories and studies, ensuring consistency and reliability in scientific research.<br />
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==History==<br />
The concept of the amount of substance and the mole has evolved over time. The term "mole" was first introduced in the early 20th century as scientists sought a standard unit to express quantities of atoms and molecules. The definition of the mole has been refined several times, with the most recent change in 2019, when the Avogadro constant was redefined based on a fixed numerical value, marking a significant shift from the empirical methods previously used to determine the amount of substance.<br />
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==Conclusion==<br />
The amount of substance is a fundamental concept in the sciences, providing a bridge between the microscopic world of atoms and molecules and the macroscopic world of chemical substances. The mole, as its SI unit, plays a critical role in the quantification and understanding of chemical and physical processes.<br />
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[[Category:Chemistry]]<br />
[[Category:Physics]]<br />
[[Category:Units of measurement]]<br />
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