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Alpidem - Revision history
2026-05-14T03:19:35Z
Revision history for this page on the wiki
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Prab: CSV import
2025-02-20T00:59:09Z
<p>CSV import</p>
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<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 00:59, 20 February 2025</td>
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Prab
https://wikimd.org/index.php?title=Alpidem&diff=6330750&oldid=prev
Prab: CSV import
2025-02-20T00:44:27Z
<p>CSV import</p>
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<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 00:44, 20 February 2025</td>
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https://wikimd.org/index.php?title=Alpidem&diff=6292540&oldid=prev
Prab: CSV import
2025-02-13T04:03:26Z
<p>CSV import</p>
<p><b>New page</b></p><div>{{Short description|Anxiolytic drug}}<br />
{{Drugbox<br />
| image = Alpidem.svg<br />
| image_size = 200px<br />
| image_alt = Chemical structure of Alpidem<br />
}}<br />
<br />
'''Alpidem''' is a [[pharmacological]] agent that belongs to the class of [[anxiolytic]] drugs. It was developed as a non-[[benzodiazepine]] anxiolytic, primarily used for the treatment of [[anxiety disorders]].<br />
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==Pharmacology==<br />
Alpidem acts as a selective [[agonist]] at the [[GABA_A receptor]], which is a major inhibitory [[neurotransmitter]] receptor in the [[central nervous system]]. Unlike traditional benzodiazepines, alpidem has a unique chemical structure that allows it to bind selectively to certain subtypes of the GABA_A receptor, potentially offering anxiolytic effects with a reduced risk of [[sedation]] and [[dependence]].<br />
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==Clinical Use==<br />
Alpidem was initially marketed for the treatment of anxiety disorders, offering an alternative to benzodiazepines. Its selective action was thought to provide anxiolytic benefits without the common side effects associated with benzodiazepines, such as [[drowsiness]] and [[muscle relaxation]].<br />
<br />
==Side Effects==<br />
Common side effects of alpidem include [[dizziness]], [[headache]], and [[nausea]]. In some cases, patients may experience [[gastrointestinal]] disturbances or [[allergic reactions]]. Due to its action on the central nervous system, there is also a potential for [[psychological dependence]].<br />
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==Regulatory Status==<br />
Alpidem was withdrawn from the market in several countries due to concerns about [[hepatotoxicity]] and other adverse effects. Its use is currently restricted or banned in many regions, and it is not widely available for clinical use.<br />
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==Chemical Properties==<br />
Alpidem is chemically distinct from benzodiazepines, featuring a unique structure that contributes to its selective receptor binding. The chemical formula of alpidem is C21H23ClN4O, and it is typically synthesized in a laboratory setting.<br />
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==Related pages==<br />
* [[Anxiolytic]]<br />
* [[GABA_A receptor]]<br />
* [[Benzodiazepine]]<br />
* [[Hepatotoxicity]]<br />
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[[Category:Anxiolytics]]<br />
[[Category:Withdrawn drugs]]</div>
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