https://wikimd.org/index.php?action=history&feed=atom&title=Allylnorpethidine 2026-04-26T23:20:12Z Revision history for this page on the wiki MediaWiki 1.44.2 https://wikimd.org/index.php?title=Allylnorpethidine&diff=5831203&oldid=prev 2024-05-27T01:08:03Z

<p>CSV import</p> <p><b>New page</b></p><div>[[File:WIN-7681.svg|thumb|WIN-7681|right]]&lt;br&gt;&#039;&#039;&#039;Allylnorpethidine&#039;&#039;&#039; is a synthetic opioid analgesic that is structurally related to [[pethidine]] (also known as meperidine). It is part of the [[4-phenylpiperidine]] class of opioids and has been studied for its potential use in pain management.<br /> == Chemical Structure and Properties ==<br /> Allylnorpethidine is chemically known as 4-phenyl-1-(2-propenyl)-4-piperidinecarboxylic acid ethyl ester. It is a derivative of pethidine, where the N-methyl group is replaced by an allyl group. This modification alters its pharmacological properties compared to pethidine.<br /> == Pharmacology ==<br /> As an opioid, allylnorpethidine acts primarily on the [[mu-opioid receptor]]s in the [[central nervous system]] to produce analgesia. Its efficacy and potency in comparison to other opioids like [[morphine]] and pethidine have been subjects of research. The presence of the allyl group may influence its binding affinity and metabolic stability.<br /> == Medical Use ==<br /> Allylnorpethidine has been investigated for its potential use in the treatment of moderate to severe pain. However, its clinical use is limited, and it is not as widely used as other opioids such as [[morphine]] or [[fentanyl]]. The side effect profile, including the risk of [[opioid addiction]] and [[respiratory depression]], is a significant consideration in its medical application.<br /> == Side Effects ==<br /> The side effects of allylnorpethidine are similar to those of other opioids and may include:<br /> * [[Nausea]]<br /> * [[Vomiting]]<br /> * [[Constipation]]<br /> * [[Drowsiness]]<br /> * [[Respiratory depression]]<br /> * [[Addiction]]<br /> == Legal Status ==<br /> The legal status of allylnorpethidine varies by country. In many jurisdictions, it is classified as a controlled substance due to its potential for abuse and addiction.<br /> == See Also ==<br /> * [[Opioid]]<br /> * [[Pethidine]]<br /> * [[Analgesic]]<br /> * [[Mu-opioid receptor]]<br /> * [[Opioid addiction]]<br /> == References ==<br /> {{Reflist}}<br /> {{Commons category|Allylnorpethidine}}<br /> [[Category:Opioids]]<br /> [[Category:Synthetic opioids]]<br /> [[Category:Analgesics]]<br /> [[Category:4-Phenylpiperidines]]<br /> [[Category:Controlled substances]]<br /> {{medicine-stub}}</div>

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