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	<title>ATF1 - Revision history</title>
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	<updated>2026-05-13T08:35:50Z</updated>
	<subtitle>Revision history for this page on the wiki</subtitle>
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	<entry>
		<id>https://wikimd.org/index.php?title=ATF1&amp;diff=6497273&amp;oldid=prev</id>
		<title>Prab: CSV import</title>
		<link rel="alternate" type="text/html" href="https://wikimd.org/index.php?title=ATF1&amp;diff=6497273&amp;oldid=prev"/>
		<updated>2025-03-17T03:36:30Z</updated>

		<summary type="html">&lt;p&gt;CSV import&lt;/p&gt;
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				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;← Older revision&lt;/td&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 03:36, 17 March 2025&lt;/td&gt;
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&lt;/table&gt;</summary>
		<author><name>Prab</name></author>
	</entry>
	<entry>
		<id>https://wikimd.org/index.php?title=ATF1&amp;diff=6202835&amp;oldid=prev</id>
		<title>Prab: CSV import</title>
		<link rel="alternate" type="text/html" href="https://wikimd.org/index.php?title=ATF1&amp;diff=6202835&amp;oldid=prev"/>
		<updated>2025-02-10T05:04:01Z</updated>

		<summary type="html">&lt;p&gt;CSV import&lt;/p&gt;
&lt;table style=&quot;background-color: #fff; color: #202122;&quot; data-mw=&quot;interface&quot;&gt;
				&lt;col class=&quot;diff-marker&quot; /&gt;
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				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;← Older revision&lt;/td&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 05:04, 10 February 2025&lt;/td&gt;
				&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot; id=&quot;mw-diff-left-l41&quot;&gt;Line 41:&lt;/td&gt;
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&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;{{medicine-stub}}&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;{{medicine-stub}}&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
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&lt;/table&gt;</summary>
		<author><name>Prab</name></author>
	</entry>
	<entry>
		<id>https://wikimd.org/index.php?title=ATF1&amp;diff=5378338&amp;oldid=prev</id>
		<title>Prab: CSV import</title>
		<link rel="alternate" type="text/html" href="https://wikimd.org/index.php?title=ATF1&amp;diff=5378338&amp;oldid=prev"/>
		<updated>2024-03-09T21:42:01Z</updated>

		<summary type="html">&lt;p&gt;CSV import&lt;/p&gt;
&lt;p&gt;&lt;b&gt;New page&lt;/b&gt;&lt;/p&gt;&lt;div&gt;&amp;#039;&amp;#039;&amp;#039;ATF1&amp;#039;&amp;#039;&amp;#039; (Activating Transcription Factor 1) is a [[protein]] that in humans is encoded by the &amp;#039;&amp;#039;ATF1&amp;#039;&amp;#039; [[gene]]. It is a member of the [[leucine zipper]] family of DNA binding proteins and interacts with the [[cAMP]] response element binding protein (CREB). The encoded protein is involved in various cellular processes, including [[cell proliferation]], [[transformation]], and [[apoptosis]].&lt;br /&gt;
&lt;br /&gt;
== Function ==&lt;br /&gt;
&lt;br /&gt;
ATF1 is a [[transcription factor]] that binds to the [[cAMP]] response element (CRE), a sequence present in many viral and cellular promoters. Studies in mice suggest that the protein encoded by this gene is important for the establishment of the [[blood-brain barrier]], and may play a role in carrying out the normal functions of the [[hypothalamus]].&lt;br /&gt;
&lt;br /&gt;
== Clinical significance ==&lt;br /&gt;
&lt;br /&gt;
ATF1 is implicated in the development of several types of [[cancer]], including [[melanoma]], [[angiosarcoma]], and [[lung cancer]]. It is also associated with [[FUS]] in liposarcoma and [[EWSR1]] in clear cell sarcoma, which are both types of [[soft tissue sarcoma]].&lt;br /&gt;
&lt;br /&gt;
== Interactions ==&lt;br /&gt;
&lt;br /&gt;
ATF1 has been shown to [[Protein-protein interaction|interact]] with:&lt;br /&gt;
* [[CREB1]]&lt;br /&gt;
* [[JUN]]&lt;br /&gt;
* [[FOS]]&lt;br /&gt;
* [[DDIT3]]&lt;br /&gt;
* [[ATF2]]&lt;br /&gt;
* [[ATF3]]&lt;br /&gt;
* [[ATF4]]&lt;br /&gt;
* [[ATF6]]&lt;br /&gt;
* [[ATF7]]&lt;br /&gt;
&lt;br /&gt;
== See also ==&lt;br /&gt;
&lt;br /&gt;
* [[Activating transcription factor]]&lt;br /&gt;
* [[cAMP responsive element binding protein]]&lt;br /&gt;
* [[Leucine zipper]]&lt;br /&gt;
&lt;br /&gt;
== References ==&lt;br /&gt;
&lt;br /&gt;
{{Reflist}}&lt;br /&gt;
&lt;br /&gt;
== External links ==&lt;br /&gt;
&lt;br /&gt;
* [https://www.ncbi.nlm.nih.gov/gene/466 ATF1] at the US National Library of Medicine [[Medical Subject Headings]] (MeSH)&lt;br /&gt;
&lt;br /&gt;
[[Category:Transcription factors]]&lt;br /&gt;
[[Category:Human proteins]]&lt;br /&gt;
[[Category:Genes on human chromosome 12]]&lt;br /&gt;
&lt;br /&gt;
{{medicine-stub}}&lt;/div&gt;</summary>
		<author><name>Prab</name></author>
	</entry>
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