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	<id>https://wikimd.org/index.php?action=history&amp;feed=atom&amp;title=AKS-452</id>
	<title>AKS-452 - Revision history</title>
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	<updated>2026-04-30T04:19:34Z</updated>
	<subtitle>Revision history for this page on the wiki</subtitle>
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	<entry>
		<id>https://wikimd.org/index.php?title=AKS-452&amp;diff=6496470&amp;oldid=prev</id>
		<title>Prab: CSV import</title>
		<link rel="alternate" type="text/html" href="https://wikimd.org/index.php?title=AKS-452&amp;diff=6496470&amp;oldid=prev"/>
		<updated>2025-03-17T02:53:27Z</updated>

		<summary type="html">&lt;p&gt;CSV import&lt;/p&gt;
&lt;table style=&quot;background-color: #fff; color: #202122;&quot; data-mw=&quot;interface&quot;&gt;
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				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;← Older revision&lt;/td&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 02:53, 17 March 2025&lt;/td&gt;
				&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot; id=&quot;mw-diff-left-l30&quot;&gt;Line 30:&lt;/td&gt;
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&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;{{pharmacology-stub}}&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;{{pharmacology-stub}}&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
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&lt;/table&gt;</summary>
		<author><name>Prab</name></author>
	</entry>
	<entry>
		<id>https://wikimd.org/index.php?title=AKS-452&amp;diff=6202516&amp;oldid=prev</id>
		<title>Prab: CSV import</title>
		<link rel="alternate" type="text/html" href="https://wikimd.org/index.php?title=AKS-452&amp;diff=6202516&amp;oldid=prev"/>
		<updated>2025-02-10T04:56:30Z</updated>

		<summary type="html">&lt;p&gt;CSV import&lt;/p&gt;
&lt;table style=&quot;background-color: #fff; color: #202122;&quot; data-mw=&quot;interface&quot;&gt;
				&lt;col class=&quot;diff-marker&quot; /&gt;
				&lt;col class=&quot;diff-content&quot; /&gt;
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				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;← Older revision&lt;/td&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 04:56, 10 February 2025&lt;/td&gt;
				&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot; id=&quot;mw-diff-left-l29&quot;&gt;Line 29:&lt;/td&gt;
&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Line 29:&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;br&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;br&gt;&lt;/td&gt;&lt;/tr&gt;
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&lt;/table&gt;</summary>
		<author><name>Prab</name></author>
	</entry>
	<entry>
		<id>https://wikimd.org/index.php?title=AKS-452&amp;diff=5373926&amp;oldid=prev</id>
		<title>Prab: CSV import</title>
		<link rel="alternate" type="text/html" href="https://wikimd.org/index.php?title=AKS-452&amp;diff=5373926&amp;oldid=prev"/>
		<updated>2024-03-08T14:13:32Z</updated>

		<summary type="html">&lt;p&gt;CSV import&lt;/p&gt;
&lt;p&gt;&lt;b&gt;New page&lt;/b&gt;&lt;/p&gt;&lt;div&gt;&amp;#039;&amp;#039;&amp;#039;AKS-452&amp;#039;&amp;#039;&amp;#039; is an experimental [[drug]] currently under investigation for its potential use in the treatment of [[COVID-19]]. It is a small molecule [[protease inhibitor]] that targets the main protease (Mpro) of the [[SARS-CoV-2]] virus, which is responsible for the replication and transcription of the virus.&lt;br /&gt;
&lt;br /&gt;
== Mechanism of Action ==&lt;br /&gt;
&lt;br /&gt;
The main protease of SARS-CoV-2 is a key enzyme that plays a crucial role in mediating viral replication and transcription. AKS-452 inhibits this enzyme, thereby preventing the virus from replicating within the host cell. This mechanism of action is similar to that of other protease inhibitors used in the treatment of viral infections such as [[HIV]] and [[Hepatitis C]].&lt;br /&gt;
&lt;br /&gt;
== Clinical Trials ==&lt;br /&gt;
&lt;br /&gt;
As of the time of writing, AKS-452 is in the early stages of clinical development. Preliminary studies have shown promising results, with the drug demonstrating potent antiviral activity against SARS-CoV-2. However, further research is needed to confirm these findings and to determine the safety and efficacy of the drug in humans.&lt;br /&gt;
&lt;br /&gt;
== Potential Applications ==&lt;br /&gt;
&lt;br /&gt;
If proven effective, AKS-452 could have significant implications for the treatment of COVID-19. It could potentially be used in combination with other antiviral drugs to enhance treatment outcomes. Moreover, given its mechanism of action, it may also have potential use in the treatment of other viral infections caused by viruses that utilize a similar replication mechanism.&lt;br /&gt;
&lt;br /&gt;
== See Also ==&lt;br /&gt;
&lt;br /&gt;
* [[COVID-19 treatment]]&lt;br /&gt;
* [[Protease inhibitor]]&lt;br /&gt;
* [[SARS-CoV-2]]&lt;br /&gt;
&lt;br /&gt;
== References ==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;references /&amp;gt;&lt;br /&gt;
&lt;br /&gt;
[[Category:Experimental drugs]]&lt;br /&gt;
[[Category:COVID-19]]&lt;br /&gt;
[[Category:Protease inhibitors]]&lt;br /&gt;
[[Category:Antiviral drugs]]&lt;br /&gt;
&lt;br /&gt;
{{pharmacology-stub}}&lt;/div&gt;</summary>
		<author><name>Prab</name></author>
	</entry>
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