https://wikimd.org/index.php?action=history&feed=atom&title=ADP%2FATP_translocase_2 ADP/ATP translocase 2 - Revision history 2026-04-30T06:43:21Z Revision history for this page on the wiki MediaWiki 1.44.2 https://wikimd.org/index.php?title=ADP/ATP_translocase_2&diff=6496480&oldid=prev Prab: CSV import 2025-03-17T02:53:41Z <p>CSV import</p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 02:53, 17 March 2025</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l35">Line 35:</td> <td colspan="2" class="diff-lineno">Line 35:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; 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white-space: pre-wrap;"><div>{{medicine-stub}}</div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">{{No image}}</ins></div></td></tr> </table> Prab https://wikimd.org/index.php?title=ADP/ATP_translocase_2&diff=5378264&oldid=prev Prab: CSV import 2024-03-09T21:37:14Z <p>CSV import</p> <p><b>New page</b></p><div>&#039;&#039;&#039;ADP/ATP translocase 2&#039;&#039;&#039; (also known as &#039;&#039;&#039;ANT2&#039;&#039;&#039;) is a [[protein]] that in humans is encoded by the SLC25A5 [[gene]]. This protein is a member of the [[mitochondrial carrier subfamily]] of solute carrier family 25. <br /> <br /> == Function ==<br /> <br /> ADP/ATP translocase 2 is an integral [[membrane protein]] that catalyzes the exchange of [[adenosine diphosphate]] (ADP) and [[adenosine triphosphate]] (ATP) across the [[mitochondrial inner membrane]]. This exchange process is a critical step in [[mitochondrial respiration]] and [[cellular metabolism]], as it allows ATP produced in the mitochondrial matrix to be transported into the cytosol where it can be used for energy-requiring processes, while simultaneously importing ADP into the matrix to be re-phosphorylated.<br /> <br /> == Structure ==<br /> <br /> The ANT2 protein is composed of six [[transmembrane domain]]s, with the N- and C-termini located in the [[cytoplasm]]. The transmembrane domains form a cavity in the center of the protein that allows for the passage of ADP and ATP.<br /> <br /> == Clinical significance ==<br /> <br /> Mutations in the SLC25A5 gene have been associated with [[Amelogenesis imperfecta]], a condition affecting the formation of [[enamel]] on teeth. Additionally, altered expression of ANT2 has been observed in several types of [[cancer]], suggesting a potential role in [[tumor]] growth and survival.<br /> <br /> == See also ==<br /> <br /> * [[ADP/ATP translocase]]<br /> * [[Mitochondrial carrier]]<br /> * [[SLC25A5]]<br /> <br /> == References ==<br /> <br /> &lt;references /&gt;<br /> <br /> == External links ==<br /> <br /> * [https://www.ncbi.nlm.nih.gov/gene/292 Human SLC25A5 gene details page] in the [[National Center for Biotechnology Information]] (NCBI) database<br /> <br /> [[Category:Membrane proteins]]<br /> [[Category:Mitochondrial proteins]]<br /> [[Category:Solute carrier family]]<br /> [[Category:Genes on human chromosome X]]<br /> <br /> {{membrane-protein-stub}}<br /> {{medicine-stub}}</div> Prab