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ADCYAP1R1 - Revision history
2026-04-21T16:16:51Z
Revision history for this page on the wiki
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2025-03-17T02:58:53Z
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<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 02:58, 17 March 2025</td>
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2025-02-10T04:52:09Z
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2024-02-28T22:25:11Z
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<p><b>New page</b></p><div>'''ADCYAP1R1''' (Adenylate Cyclase Activating Polypeptide 1 Receptor 1) is a [[protein]] that in humans is encoded by the ADCYAP1R1 [[gene]]. This receptor is a member of the [[G protein-coupled receptor]] family, and is involved in a variety of physiological processes.<br />
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== Function ==<br />
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The ADCYAP1R1 receptor is primarily involved in the regulation of [[adenylate cyclase]] activity. This is achieved through the binding of its ligand, [[pituitary adenylate cyclase activating polypeptide]] (PACAP). PACAP is a potent activator of adenylate cyclase, and its interaction with ADCYAP1R1 can lead to increased levels of [[cyclic AMP]] in the cell.<br />
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== Clinical Significance ==<br />
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Mutations in the ADCYAP1R1 gene have been associated with a number of disorders. These include [[post-traumatic stress disorder]] (PTSD), [[migraine]], and certain forms of [[anxiety disorder]]. Research is ongoing to further understand the role of this receptor in these conditions.<br />
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== See Also ==<br />
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* [[G protein-coupled receptor]]<br />
* [[Adenylate cyclase]]<br />
* [[Pituitary adenylate cyclase activating polypeptide]]<br />
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== References ==<br />
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{{Reflist}}<br />
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[[Category:G protein-coupled receptors]]<br />
[[Category:Human proteins]]<br />
{{protein-stub}}</div>
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