https://wikimd.org/index.php?action=history&feed=atom&title=ACSF3 2026-05-12T12:37:16Z Revision history for this page on the wiki MediaWiki 1.44.2 https://wikimd.org/index.php?title=ACSF3&diff=6497472&oldid=prev 2025-03-17T03:45:36Z

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<p>CSV import</p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 04:56, 10 February 2025</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l27">Line 27:</td> <td colspan="2" class="diff-lineno">Line 27:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{medicine-stub}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{medicine-stub}}</div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">{{No image}}</ins></div></td></tr> </table>

Prab https://wikimd.org/index.php?title=ACSF3&diff=5378180&oldid=prev 2024-03-09T21:30:37Z

<p>CSV import</p> <p><b>New page</b></p><div>== ACSF3 ==<br /> <br /> [[ACSF3]], or Acyl-CoA Synthetase Family Member 3, is a [[gene]] that encodes a member of the acyl-CoA synthetase family of enzymes. These enzymes catalyze the reaction of ATP and a long-chain [[fatty acid]] to form an acyl-CoA, AMP, and pyrophosphate. The encoded protein is localized to [[mitochondria]] and plays a key role in fatty acid metabolism in these organelles.<br /> <br /> == Function ==<br /> <br /> The ACSF3 gene is responsible for the production of an enzyme that is involved in the metabolism of fatty acids. This enzyme is found in the mitochondria, the energy-producing centers of cells. It is involved in the breakdown of certain types of fatty acids, specifically very long-chain fatty acids, which are fats that have a chain length of more than 22 carbon atoms.<br /> <br /> == Clinical significance ==<br /> <br /> Mutations in the ACSF3 gene have been associated with [[Combined Malonic and Methylmalonic Aciduria]] (CMAMMA), a rare metabolic disorder. This condition is characterized by elevated levels of malonic acid and methylmalonic acid in the urine. Symptoms of CMAMMA can include developmental delay, failure to thrive, and signs of metabolic acidosis.<br /> <br /> == See also ==<br /> <br /> * [[Acyl-CoA synthetase]]<br /> * [[Fatty acid metabolism]]<br /> * [[Mitochondria]]<br /> * [[Combined Malonic and Methylmalonic Aciduria]]<br /> <br /> == References ==<br /> <br /> &lt;references /&gt;<br /> <br /> [[Category:Genes]]<br /> [[Category:Metabolic disorders]]<br /> [[Category:Mitochondrial diseases]]<br /> <br /> {{medicine-stub}}</div>

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