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	<id>https://wikimd.org/index.php?action=history&amp;feed=atom&amp;title=ACAT2</id>
	<title>ACAT2 - Revision history</title>
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	<updated>2026-05-11T09:27:12Z</updated>
	<subtitle>Revision history for this page on the wiki</subtitle>
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	<entry>
		<id>https://wikimd.org/index.php?title=ACAT2&amp;diff=6496618&amp;oldid=prev</id>
		<title>Prab: CSV import</title>
		<link rel="alternate" type="text/html" href="https://wikimd.org/index.php?title=ACAT2&amp;diff=6496618&amp;oldid=prev"/>
		<updated>2025-03-17T02:58:15Z</updated>

		<summary type="html">&lt;p&gt;CSV import&lt;/p&gt;
&lt;table style=&quot;background-color: #fff; color: #202122;&quot; data-mw=&quot;interface&quot;&gt;
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				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;← Older revision&lt;/td&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 02:58, 17 March 2025&lt;/td&gt;
				&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot; id=&quot;mw-diff-left-l31&quot;&gt;Line 31:&lt;/td&gt;
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&lt;/table&gt;</summary>
		<author><name>Prab</name></author>
	</entry>
	<entry>
		<id>https://wikimd.org/index.php?title=ACAT2&amp;diff=6202292&amp;oldid=prev</id>
		<title>Prab: CSV import</title>
		<link rel="alternate" type="text/html" href="https://wikimd.org/index.php?title=ACAT2&amp;diff=6202292&amp;oldid=prev"/>
		<updated>2025-02-10T04:51:25Z</updated>

		<summary type="html">&lt;p&gt;CSV import&lt;/p&gt;
&lt;table style=&quot;background-color: #fff; color: #202122;&quot; data-mw=&quot;interface&quot;&gt;
				&lt;col class=&quot;diff-marker&quot; /&gt;
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				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;← Older revision&lt;/td&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 04:51, 10 February 2025&lt;/td&gt;
				&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot; id=&quot;mw-diff-left-l30&quot;&gt;Line 30:&lt;/td&gt;
&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Line 30:&lt;/td&gt;&lt;/tr&gt;
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&lt;/table&gt;</summary>
		<author><name>Prab</name></author>
	</entry>
	<entry>
		<id>https://wikimd.org/index.php?title=ACAT2&amp;diff=5377728&amp;oldid=prev</id>
		<title>Prab: CSV import</title>
		<link rel="alternate" type="text/html" href="https://wikimd.org/index.php?title=ACAT2&amp;diff=5377728&amp;oldid=prev"/>
		<updated>2024-03-09T20:59:23Z</updated>

		<summary type="html">&lt;p&gt;CSV import&lt;/p&gt;
&lt;p&gt;&lt;b&gt;New page&lt;/b&gt;&lt;/p&gt;&lt;div&gt;&amp;#039;&amp;#039;&amp;#039;ACAT2&amp;#039;&amp;#039;&amp;#039; (Acetyl-CoA acetyltransferase 2) is an [[enzyme]] that in humans is encoded by the &amp;#039;&amp;#039;ACAT2&amp;#039;&amp;#039; [[gene]]. This enzyme is primarily located in the [[mitochondria]], and plays a crucial role in [[lipid metabolism]].&lt;br /&gt;
&lt;br /&gt;
== Function ==&lt;br /&gt;
&lt;br /&gt;
ACAT2 is an important enzyme involved in the [[metabolic pathway]]s of [[lipid metabolism]]. It catalyzes the reversible formation of [[acetoacetyl-CoA]] from two molecules of [[acetyl-CoA]]. This reaction is a key step in the [[mevalonate pathway]], which is responsible for the biosynthesis of [[cholesterol]], [[steroids]], and other [[isoprenoids]].&lt;br /&gt;
&lt;br /&gt;
== Clinical significance ==&lt;br /&gt;
&lt;br /&gt;
Mutations in the &amp;#039;&amp;#039;ACAT2&amp;#039;&amp;#039; gene have been associated with [[hypercholesterolemia]], a condition characterized by high levels of cholesterol in the blood. This can lead to the development of [[atherosclerosis]], a disease in which plaque builds up inside the arteries, and can potentially lead to heart disease and stroke.&lt;br /&gt;
&lt;br /&gt;
== See also ==&lt;br /&gt;
&lt;br /&gt;
* [[ACAT1]]&lt;br /&gt;
* [[Acetyl-CoA acetyltransferase]]&lt;br /&gt;
* [[Mevalonate pathway]]&lt;br /&gt;
* [[Hypercholesterolemia]]&lt;br /&gt;
* [[Atherosclerosis]]&lt;br /&gt;
&lt;br /&gt;
== References ==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;references /&amp;gt;&lt;br /&gt;
&lt;br /&gt;
== External links ==&lt;br /&gt;
&lt;br /&gt;
* [https://www.ncbi.nlm.nih.gov/gene/39 NCBI Gene]&lt;br /&gt;
* [https://www.uniprot.org/uniprot/O43734 UniProt]&lt;br /&gt;
&lt;br /&gt;
[[Category:Human proteins]]&lt;br /&gt;
[[Category:EC 2.3.1]]&lt;br /&gt;
[[Category:Genes on human chromosome 6]]&lt;br /&gt;
{{medicine-stub}}&lt;/div&gt;</summary>
		<author><name>Prab</name></author>
	</entry>
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